4.4 Article

Terragines F-G produced by endophytic Bacillus sp. SH-1.2-ROOT-18 from Dendrobium officinale

Journal

NATURAL PRODUCT RESEARCH
Volume 36, Issue 19, Pages 5058-5063

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2021.1914614

Keywords

Terragine; natural product; endophyte; Bacillus sp; Dendrobium officinale

Funding

  1. National Key RD Program [2019YFC1711500]
  2. Nature Science Foundation of Jiangsu Higher Education Institutions of China [19KJA180008]
  3. Postgraduate Research & Practice Innovation Program of Jiangsu Province [KYCX20_1584]
  4. Jiangsu Provincial Double Creation Talent Program [202010528]

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Two new terragine analogs, with special succinimide and aminopentane moieties, were isolated from the fermentation broth of Bacillus sp. SH-1.2-ROOT-18, an endophyte previously discovered from the root of Dendrobium officinale. The structures were determined through comprehensive 1D/2D NMR and MS data analysis, along with complete NMR assignments for the first reported naturally occurring metabolite 3.
Two new terragine analogs (1-2) with special succinimide and aminopentane moieties were isolated from the fermentation broth of Bacillus sp. SH-1.2-ROOT-18, an endophyte previously discovered from the root of Dendrobium officinale. The structures were elucidated base on comprehensive 1 D/2D NMR and MS data analysis. Complete NMR assignments for the first reported naturally occurring metabolite 3 was also provided.

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