Journal
MOLECULES
Volume 26, Issue 9, Pages -Publisher
MDPI
DOI: 10.3390/molecules26092709
Keywords
antioxidants; flavonoids; anti-leukemic; myeloid leukemia; lymphoblastic leukemia
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The use of biologically active compounds for the treatment of leukemia shows promise in improving therapeutic options for patients, targeting different types of leukemia cells. This review serves as a basis for further research in developing new alternative therapies in the fight against leukemia, a deadly hematological cancer.
The use of biologically active compounds has become a realistic option for the treatment of malignant tumors due to their cost-effectiveness and safety. In this review, we aimed to highlight the main natural biocompounds that target leukemic cells, assessed by in vitro and in vivo experiments or clinical studies, in order to explore their therapeutic potential in the treatment of leukemia: acute myeloid leukemia (AML), chronic myeloid leukemia (CML), acute lymphocytic leukemia (ALL), and chronic lymphocytic leukemia (CLL). It provides a basis for researchers and hematologists in improving basic and clinical research on the development of new alternative therapies in the fight against leukemia, a harmful hematological cancer and the leading cause of death among patients.
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