4.6 Review

Biocide Use in the Antimicrobial Era: A Review

Journal

MOLECULES
Volume 26, Issue 8, Pages -

Publisher

MDPI
DOI: 10.3390/molecules26082276

Keywords

biocides; bacteria; antibiotic; antimicrobial; disinfection; surfaces; transmission; chemical; resistance

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Biocides are commonly used in healthcare and industry to control infections and microbial contamination. Ineffective disinfection and misuse of biocides can lead to the survival of microorganisms on surfaces, contributing to the transmission of infectious agents. Understanding the modes of action and efficacy of biocides is crucial for their rational use and development, especially in an era where microorganisms are increasingly resistant to chemical antimicrobial agents.
Biocides are widely used in healthcare and industry to control infections and microbial contamination. Ineffectual disinfection of surfaces and inappropriate use of biocides can result in the survival of microorganisms such as bacteria and viruses on inanimate surfaces, often contributing to the transmission of infectious agents. Biocidal disinfectants employ varying modes of action to kill microorganisms, ranging from oxidization to solubilizing lipids. This review considers the main biocides used within healthcare and industry environments and highlights their modes of action, efficacy and relevance to disinfection of pathogenic bacteria. This information is vital for rational use and development of biocides in an era where microorganisms are becoming resistant to chemical antimicrobial agents.

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