Journal
MOLECULES
Volume 26, Issue 6, Pages -Publisher
MDPI
DOI: 10.3390/molecules26061596
Keywords
human milk fat; fat globule size; phospholipids; compositional correlation; HPLC-ELSD; P-31 NMR
Funding
- Maeil Innovation Center (MIC), Maeil Dairies Co., Ltd., Korea
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The study found a positive correlation between fat content and phospholipid content in human milk, with fat droplet size having a smaller impact on fat content. Furthermore, the composition and content of different phospholipid species in human milk varied according to fat content.
Fat globule size and phospholipid (PL) content in human milk (HM) were investigated. HM was classified into three groups depending on fat content (A < B < C). PL content (mg/100 g HM) was significantly higher in the C group (p < 0.05), indicating its positive relationship with HM fat content. When the PL content was normalized (mg/g fat), that of group A was significantly higher (p < 0.05) and fat droplet size in group C was slightly larger, suggesting that HM fat content is affected by fat droplet numbers to a larger extent than by fat droplet size. A correlation between PC and SM content in HM was observed regardless of fat content, while correlation between PE and either PC or SM increased in the order of C > B > A, hence the composition and content of PL species in HM varied according to its fat content.
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