1,3-Cyclohexadien-1-Als: Synthesis, Reactivity and Bioactivities

In synthetic organic chemistry, there are very useful basic compounds known as building blocks. One of the main reactions wherein they are applied for the synthesis of complex molecules is the Diels-Alder cycloaddition. This reaction is between a diene and a dienophile. Among the most important dienes are the cyclic dienes, as they facilitate the reaction. This review considers the synthesis and reactivity of one of these dienes with special characteristics-it is cyclic and has an electron withdrawing group. This building block has been used for the synthesis of biologically active compounds and is present in natural compounds with interesting properties.

Automated summary

Building blocks play a crucial role in synthetic organic chemistry, with the Diels-Alder cycloaddition reaction being a common application. Cyclic dienes are important for facilitating this reaction. By utilizing cyclic dienes with unique characteristics, biologically active compounds with interesting properties can be synthesized.