Related references
Note: Only part of the references are listed.Emerging Role of Sirtuin 2 in Parkinson's Disease
Yumei Liu et al.
FRONTIERS IN AGING NEUROSCIENCE (2020)
Taraxasterol protects hippocampal neurons from oxygen-glucose deprivation-induced injury through activation of Nrf2 signalling pathway
Yun He et al.
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2020)
Structural Insight into the Interactions between Structurally Similar Inhibitors and SIRT6
Shuang Zhao et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Aβ-Induced Damage Memory in hCMEC/D3 Cells Mediated by Sirtuin-1
Haochen Liu et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Evaluation of the Neuroprotective Effect of Sirt3 in Experimental Stroke
Rajkumar Verma et al.
TRANSLATIONAL STROKE RESEARCH (2019)
NAD+ metabolism as a target for metabolic health: have we found the silver bullet?
Niels J. Connell et al.
DIABETOLOGIA (2019)
Molecular Mechanisms of TDP-43 Misfolding and Pathology in Amyotrophic Lateral Sclerosis
Archana Prasad et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2019)
An overview of Sirtuins as potential therapeutic target: Structure, function and modulators
Yijie Wang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Echinacoside protects against MPTP/MPP+-induced neurotoxicity via regulating autophagy pathway mediated by Sirt1
Chang Chen et al.
METABOLIC BRAIN DISEASE (2019)
Dichotomous Sirtuins: Implications for Drug Discovery in Neurodegenerative and Cardiometabolic Diseases
Pedro Gomes et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2019)
Epigenetic Mechanisms of Ischemic Stroke
A. B. Uzdensky et al.
BIOCHEMISTRY MOSCOW SUPPLEMENT SERIES A-MEMBRANE AND CELL BIOLOGY (2019)
SIRT2 Inhibition Confers Neuroprotection by Downregulation of FOXO3a and MAPK Signaling Pathways in Ischemic Stroke
David T. She et al.
MOLECULAR NEUROBIOLOGY (2018)
Metabolism, neurodegeneration and epigenetics: emerging role of Sirtuins
Dafne M. Silberman
NEURAL REGENERATION RESEARCH (2018)
Sirtuin activators and inhibitors: Promises, achievements, and challenges
Han Dai et al.
PHARMACOLOGY & THERAPEUTICS (2018)
Sirtuin-4 (SIRT4), a therapeutic target with oncogenic and tumor-suppressive activity in cancer
Guoyu Huang et al.
ONCOTARGETS AND THERAPY (2018)
NAD(H) in mitochondrial energy transduction: implications for health and disease
Matthew A. Walker et al.
CURRENT OPINION IN PHYSIOLOGY (2018)
SIRT3 deregulation is linked to mitochondrial dysfunction in Alzheimer's disease
Junghee Lee et al.
AGING CELL (2018)
Function of the SIRT3 mitochondrial deacetylase in cellular physiology, cancer, and neurodegenerative disease
Aneesa Ansari et al.
AGING CELL (2017)
Sirtuins as Modifiers of Parkinson's Disease Pathology
Bor Luen Tang
JOURNAL OF NEUROSCIENCE RESEARCH (2017)
Sirtuins and Their Roles in Brain Aging and Neurodegenerative Disorders
Henryk Jesko et al.
NEUROCHEMICAL RESEARCH (2017)
Therapeutic role of sirtuins in neurodegenerative disease and their modulation by polyphenols
Marjan Ajami et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2017)
Neuroprotective Functions for the Histone Deacetylase SIRT6
Shai Kaluski et al.
CELL REPORTS (2017)
The sirtuin family members SIRT1, SIRT3 and SIRT6: Their role in vascular biology and atherogenesis
Bozena Sosnowska et al.
ATHEROSCLEROSIS (2017)
Sirtuins, a promising target in slowing down the ageing process
Wioleta Grabowska et al.
BIOGERONTOLOGY (2017)
The world of protein acetylation
Adrian Drazic et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2016)
SIRT3 Acts as a Neuroprotective Agent in Rotenone-Induced Parkinson Cell Model
Jing-Yi Zhang et al.
NEUROCHEMICAL RESEARCH (2016)
Sirtuin functions and modulation: from chemistry to the clinic
Vincenzo Carafa et al.
CLINICAL EPIGENETICS (2016)
SIRT2-and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington's Disease Models
Luisa Quinti et al.
CELL CHEMICAL BIOLOGY (2016)
Sirtuins: double players in Huntington's disease
Luana Naia et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2015)
An exploratory double-blind, randomized clinical trial with selisistat, a SirT1 inhibitor, in patients with Huntington's disease
Sigurd D. Suessmuth et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2015)
NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus
Carles Canto et al.
CELL METABOLISM (2015)
Emerging Role of Sirtuin 2 in the Regulation of Mammalian Metabolism
Pedro Gomes et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2015)
The Sirtuin-2 Inhibitor AK7 Is Neuroprotective in Models of Parkinson's Disease but Not Amyotrophic Lateral Sclerosis and Cerebral Ischemia
Xiqun Chen et al.
PLOS ONE (2015)
Erasers of Histone Acetylation: The Histone Deacetylase Enzymes
Edward Seto et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2014)
The Role of Dietary Histone Deacetylases (HDACs) Inhibitors in Health and Disease
Shalome A. Bassett et al.
NUTRIENTS (2014)
SIRT2 enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced nigrostriatal damage via apoptotic pathway
Lei Liu et al.
FRONTIERS IN AGING NEUROSCIENCE (2014)
Resveratrol Ameliorates Motor Neuron Degeneration and Improves Survival in SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis
Lin Song et al.
BIOMED RESEARCH INTERNATIONAL (2014)
Sirtuin 1 activator SRT2104 protects Huntington's disease mice
Mali Jiang et al.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2014)
SIRT5 Regulates the Mitochondrial Lysine Succinylome and Metabolic Networks
Matthew J. Rardin et al.
CELL METABOLISM (2013)
Sirtuins as therapeutic targets of ALS
Giulio Maria Pasinetti et al.
CELL RESEARCH (2013)
Sirtuin deacetylases in neurodegenerative diseases of aging
Adrianna Z. Herskovits et al.
CELL RESEARCH (2013)
Targeting Sirtuin-1 in Huntington's Disease: Rationale and Current Status
Wenzhen Duan
CNS DRUGS (2013)
Sirtuins Family-Recent Development as a Drug Target for Aging, Metabolism, and Age Related Diseases
Chiranjib Chakraborty et al.
CURRENT DRUG TARGETS (2013)
Hdac6 deletion delays disease progression in the SOD1G93A mouse model of ALS
Ines Taes et al.
HUMAN MOLECULAR GENETICS (2013)
Novel Protective Effects of Histone Deacetylase Inhibition on Stroke and White Matter Ischemic Injury
Selva Baltan et al.
NEUROTHERAPEUTICS (2013)
Sirtuin Deacetylases as Therapeutic Targets in the Nervous System
Brett Langley et al.
NEUROTHERAPEUTICS (2013)
The role of sirtuins in Alzheimer's disease
Rakhee Lalla et al.
FRONTIERS IN AGING NEUROSCIENCE (2013)
Sirtuins in neurodegenerative diseases: an update on potential mechanisms
Sang-Won Min et al.
FRONTIERS IN AGING NEUROSCIENCE (2013)
Sirtuin activators and inhibitors
Jose M. Villalba et al.
BIOFACTORS (2012)
Mitochondrial sirtuins - a new therapeutic target for repair and protection in multiple sclerosis
C. M. Rice et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2012)
Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets
Mali Jiang et al.
NATURE MEDICINE (2012)
Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway
Hyunkyung Jeong et al.
NATURE MEDICINE (2012)
Sirtuins in Neurodegenerative Diseases: A Biological-Chemical Perspective
Aparna Raghavan et al.
NEURODEGENERATIVE DISEASES (2012)
SIRTUIN 1 AND SIRTUIN 3: PHYSIOLOGICAL MODULATORS OF METABOLISM
Ruben Nogueiras et al.
PHYSIOLOGICAL REVIEWS (2012)
The neurobiology of sirtuins and their role in neurodegeneration
Gizem Donmez
TRENDS IN PHARMACOLOGICAL SCIENCES (2012)
Epigenetic histone acetylation and deacetylation mechanisms in experimental models of neurodegenerative disorders
Zacharoula Konsoula et al.
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS (2012)
Inhibition of sirtuin 2 with sulfobenzoic acid derivative AK1 is non-toxic and potentially neuroprotective in a mouse model of frontotemporal dementia
Tara L. Spires-Jones et al.
FRONTIERS IN PHARMACOLOGY (2012)
SIRT2 as a therapeutic target for age-related disorders
Rita Machado de Oliveira et al.
FRONTIERS IN PHARMACOLOGY (2012)
Targeting Sirtuin 1 to Improve Metabolism: All You Need Is NAD+?
Carles Canto et al.
PHARMACOLOGICAL REVIEWS (2012)
Sirtuins: Molecular Traffic Lights in the Crossroad of Oxidative Stress, Chromatin Remodeling, and Transcription
Ramkumar Rajendran et al.
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2011)
Sirtuins at a glance
Takashi Nakagawa et al.
JOURNAL OF CELL SCIENCE (2011)
SIRT6 Promotes DNA Repair Under Stress by Activating PARP1
Zhiyong Mao et al.
SCIENCE (2011)
Sirtuin-1 regulation of mammalian metabolism
Matthew P. Gillum et al.
TRENDS IN MOLECULAR MEDICINE (2011)
Mammalian Sirtuins: Biological Insights and Disease Relevance
Marcia C. Haigis et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2010)
Mitochondrial SIRT3 and heart disease
Vinodkumar B. Pillai et al.
CARDIOVASCULAR RESEARCH (2010)
Resveratrol protects against peripheral deficits in a mouse model of Huntington's disease
Daniel J. Ho et al.
EXPERIMENTAL NEUROLOGY (2010)
AMP-activated Protein Kinase Signaling Activation by Resveratrol Modulates Amyloid-β Peptide Metabolism
Valerie Vingtdeux et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
A Single-Dose Resveratrol Treatment in a Mouse Model of Amyotrophic Lateral Sclerosis
Chad D. Markert et al.
JOURNAL OF MEDICINAL FOOD (2010)
Benefits of histone deacetylase inhibitors for acute brain injury: a systematic review of animal studies
Claire L. Gibson et al.
JOURNAL OF NEUROCHEMISTRY (2010)
Icariin protects against brain injury by enhancing SIRT1-dependent PGC-1α Expression in experimental stroke
Hai-rong Zhu et al.
NEUROPHARMACOLOGY (2010)
Silent information regulator, Sirtuin 1, and age-related diseases
Li Zeng et al.
GERIATRICS & GERONTOLOGY INTERNATIONAL (2009)
Potential Role of Sirtuin as a Therapeutic Target for Neurodegenerative Diseases
Seol-Heui Han
JOURNAL OF CLINICAL NEUROLOGY (2009)
The SIRT1 activator resveratrol protects SK-N-BE cells from oxidative stress and against toxicity caused by α-synuclein or amyloid-β (1-42) peptide
Diego Albani et al.
JOURNAL OF NEUROCHEMISTRY (2009)
SIRTUIN 1: Regulating the regulator
Barbara Zschoernig et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Therapeutic role of sirtuins in neurodegenerative disease
Tiago Fleming Outeiro et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2008)
Biological and Potential Therapeutic Roles of Sirtuin Deacetylases
D. M. Taylor et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2008)
Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington's disease
Judit Pallos et al.
HUMAN MOLECULAR GENETICS (2008)
Resveratrol attenuates ischemic brain damage in the delayed phase after stroke and induces messenger RNA and protein express for angiogenic factors
WenPeng Dong et al.
JOURNAL OF VASCULAR SURGERY (2008)
A new penumbra: transitioning from injury into repair after stroke
Eng H. Lo
NATURE MEDICINE (2008)
Sirtuins - novel therapeutic targets to treat age-associated diseases
Siva Lavu et al.
NATURE REVIEWS DRUG DISCOVERY (2008)
Resveratrol, a red wine polyphenol, protects dopaminergic neurons in MPTP-treated mice
Julie Blanchet et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2008)
Interphase Nucleo-Cytoplasmic Shuttling and Localization of SIRT2 during Mitosis
Brian J. North et al.
PLOS ONE (2007)
Sirtuin 2 inhibitors rescue α-synuclein-mediated toxicity in models of Parkinson's disease
Tiago Fleming Outeiro et al.
SCIENCE (2007)
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis
Dohoon Kim et al.
EMBO JOURNAL (2007)
SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress
Michael B. Scher et al.
GENES & DEVELOPMENT (2007)
Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1α in Huntington's disease neurodegeneration
Patrick Weydt et al.
CELL METABOLISM (2006)
Genetics of familial and sporadic amyotrophic lateral sclerosis
Francois Gros-Louis et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2006)
Transcriptional repression of PGC-α by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration
Libin Cui et al.
CELL (2006)
Effect of resveratral on 3-nitropropionic acid-induced biochemical and behavioural changes: possible neuroprotective mechanisms
Puneet Kumar et al.
BEHAVIOURAL PHARMACOLOGY (2006)
Neuronal protection by sirtuins in Alzheimer's disease
TS Anekonda et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
T Araki et al.
SCIENCE (2004)