4.8 Review

Discovering the landscape of protein modifications

Related references

Note: Only part of the references are listed.
Review Clinical Neurology

Tau Post-translational Modifications: Dynamic Transformers of Tau Function, Degradation, and Aggregation

Carolina Alquezar et al.

Summary: Post-translational modifications play a crucial role in regulating tau protein function, including phosphorylation and acetylation. While these modifications may regulate protein function under normal conditions, they can be hijacked in disease states. Limited understanding exists on how these modifications impact tau protein, but studies indicate their critical role in localization, interactions, and other aspects.

FRONTIERS IN NEUROLOGY (2021)

Article Biochemistry & Molecular Biology

A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging

Haopeng Xiao et al.

Article Biotechnology & Applied Microbiology

The functional landscape of the human phosphoproteome

David Ochoa et al.

NATURE BIOTECHNOLOGY (2020)

Article Biochemistry & Molecular Biology

Spatial and temporal alterations in protein structure by EGF regulate cryptic cysteine oxidation

Jessica B. Behring et al.

SCIENCE SIGNALING (2020)

Article Multidisciplinary Sciences

A Multi-Omics Interpretable Machine Learning Model Reveals Modes of Action of Small Molecules

Natasha L. Patel-Murray et al.

SCIENTIFIC REPORTS (2020)

Review Cell Biology

The Roles of Histone Deacetylases and Their Inhibitors in Cancer Therapy

Guo Li et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)

Review Neurosciences

New Insights Into Drug Discovery Targeting Tau Protein

Yoshiyuki Soeda et al.

FRONTIERS IN MOLECULAR NEUROSCIENCE (2020)

Article Biotechnology & Applied Microbiology

TagGraph reveals vast protein modification landscapes from large tandem mass spectrometry datasets

Arun Devabhaktuni et al.

NATURE BIOTECHNOLOGY (2019)

Editorial Material Biochemical Research Methods

A dream of single-cell proteomics

Vivien Marx

NATURE METHODS (2019)

Review Biotechnology & Applied Microbiology

Research progress in protein posttranslational modification site prediction

Wenying He et al.

BRIEFINGS IN FUNCTIONAL GENOMICS (2019)

Article Biochemistry & Molecular Biology

HMDB 4.0: the human metabolome database for 2018

David S. Wishart et al.

NUCLEIC ACIDS RESEARCH (2018)

Article Biochemistry & Molecular Biology

Revealing the protein propionylation activity of the histone acetyltransferase MOF (males absent on the first)

Zhen Han et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2018)

Correction Biochemistry & Molecular Biology

p300-Mediated Lysine 2-Hydroxyisobutyrylation Regulates Glycolysis (vol 70, pg 663, 2018)

He Huang et al.

MOLECULAR CELL (2018)

Correction Biochemistry & Molecular Biology

UniProt: the universal protein knowledgebase (vol 45, pg D158, 2017)

Alexandre Renaux

NUCLEIC ACIDS RESEARCH (2018)

Review Biochemistry & Molecular Biology

Reactive Acyl-CoA Species Modify Proteins and Induce Carbon Stress

Alec G. Trub et al.

TRENDS IN BIOCHEMICAL SCIENCES (2018)

Article Multidisciplinary Sciences

Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth

Jonathan B. Baell et al.

NATURE (2018)

Review Biochemistry & Molecular Biology

The Causes and Consequences of Nonenzymatic Protein Acylation

Andrew M. James et al.

TRENDS IN BIOCHEMICAL SCIENCES (2018)

Article Multidisciplinary Sciences

Characterizing posttranslational modifications in prokaryotic metabolism using a multiscale workflow

Elizabeth Brunk et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Review Chemistry, Analytical

Mass Spectrometry Imaging: A Review of Emerging Advancements and Future Insights

Amanda Rae Buchberger et al.

ANALYTICAL CHEMISTRY (2018)

Article Biochemical Research Methods

Proteome-wide Structural Analysis of PTM Hotspots Reveals Regulatory Elements Predicted to Impact Biological Function and Disease

Matthew P. Torres et al.

MOLECULAR & CELLULAR PROTEOMICS (2016)

Article Multidisciplinary Sciences

Proteome-wide covalent ligand discovery in native biological systems

Keriann M. Backus et al.

NATURE (2016)

Editorial Material Biochemistry & Molecular Biology

Now, More Than Ever, Proteomics Needs Better Chromatography

Evgenia Shishkova et al.

CELL SYSTEMS (2016)

Review Biochemical Research Methods

Computational and statistical methods for high-throughput analysis of post-translational modifications of proteins

Veit Schwaemmle et al.

JOURNAL OF PROTEOMICS (2015)

Review Spectroscopy

SOFTWARE EYES FOR PROTEIN POST-TRANSLATIONAL MODIFICATIONS

Seungjin Na et al.

MASS SPECTROMETRY REVIEWS (2015)

Review Cell Biology

50 years of protein acetylation: from gene regulation to epigenetics, metabolism and beyond

Eric Verdin et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2015)

Article Multidisciplinary Sciences

A draft map of the human proteome

Min-Sik Kim et al.

NATURE (2014)

Article Multidisciplinary Sciences

SUMOylation at K340 inhibits tau degradation through deregulating its phosphorylation and ubiquitination

Hong-Bin Luo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Multidisciplinary Sciences

Functional Lysine Modification by an Intrinsically Reactive Primary Glycolytic Metabolite

Raymond E. Moellering et al.

SCIENCE (2013)

Article Biochemical Research Methods

Fast Multi-blind Modification Search through Tandem Mass Spectrometry

Seungjin Na et al.

MOLECULAR & CELLULAR PROTEOMICS (2012)

Review Genetics & Heredity

Histone methylation: a dynamic mark in health, disease and inheritance

Eric L. Greer et al.

NATURE REVIEWS GENETICS (2012)

Review Biochemistry & Molecular Biology

Hallmarks of Cancer: The Next Generation

Douglas Hanahan et al.

Article Biochemical Research Methods

PeaksPTM: Mass Spectrometry-Based Identification of Peptides with Unspecified Modifications

Xi Han et al.

JOURNAL OF PROTEOME RESEARCH (2011)

Review Neurosciences

The Many Faces of Tau

Meaghan Morris et al.

NEURON (2011)

Article Multidisciplinary Sciences

Quantitative reactivity profiling predicts functional cysteines in proteomes

Eranthie Weerapana et al.

NATURE (2010)

Article Multidisciplinary Sciences

Regulation of Cellular Metabolism by Protein Lysine Acetylation

Shimin Zhao et al.

SCIENCE (2010)

Article Multidisciplinary Sciences

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

Chunaram Choudhary et al.

SCIENCE (2009)

Article Biochemistry & Molecular Biology

Substrate and functional diversity of lysine acetylation revealed by a proteomics survey

Sung Chan Kim et al.

MOLECULAR CELL (2006)

Article Biochemistry & Molecular Biology

S-(2-succinyl)cysteine:: A novel chemical modification of tissue proteins by a Krebs cycle intermediate

Nathan L. Alderson et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2006)

Article Multidisciplinary Sciences

Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1

CY Gui et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Review Multidisciplinary Sciences

Mass spectrometry-based proteomics

R Aebersold et al.

NATURE (2003)