Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 116, Issue -, Pages 290-317Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.ejmech.2016.03.025
Keywords
Isocoumarins; Classification; Biological activities; Natural products
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Isocoumarins are lactonic natural products abundant in microbes and higher plants. These are considered an amazing scaffold consecrated with more or less all types of pharmacological applications. This review is complementary to the earlier reviews and aims to focus the overlooked aspects of their fascinating chemistry with special emphasis on their classification and diverse biological activities with some SAR conclusions. The most recent available literature on the structural diversity and biological activity of these natural products has been reviewed. (C) 2016 Elsevier Masson SAS. All rights reserved.
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