4.5 Article

A case report of reversible posterior encephalopathy syndrome with intracranial hemorrhage in a child

Journal

MEDICINE
Volume 100, Issue 12, Pages -

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MD.0000000000025266

Keywords

Brain damage; Child; Intracranial hemorrhage; Reversible posterior encephalopathy syndrome

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This study analyzed the clinical diagnosis and treatment of children with PRES combined with ICH, emphasizing the importance of early diagnosis and timely adjustment of medication regimen to prevent irreversible brain damage.
Introduction: The objective is to analyze the clinical diagnosis and treatment of children with rescindable posterior encephalopathy syndrome (PRES) and intracranial hemorrhage (ICH) to improve the pediatrician's understanding of PRES combined with ICH in children. Patient concerns and Diagnosis: After liver transplantation, the patient developed symptoms of epilepsy and coma. Meanwhile, massive necrosis of acute cerebral infarction and small hemorrhage was observed in the left cerebellar hemisphere and left occipital lobe, respectively. The above symptoms were initially diagnosed as PRES. Interventions and outcomes: After adjusting the anti-rejection drug regimen, it was found that the child's neurological symptoms were relieved, and the limb motor function gradually recovered during follow-up. Imaging examination showed significant improvement on abnormal signals in brain. Conclusion: In general, children with PRES may further develop ICH and contribute to a poor prognosis. Early diagnosis, detection of risk factors and timely adjustment of medication regimen are the keys to prevent irreversible brain damage.

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