Related references
Note: Only part of the references are listed.Optimisation of anti-cancer peptide vaccines to preferentially elicit high-avidity T cells
Adarsh Kumbhari et al.
JOURNAL OF THEORETICAL BIOLOGY (2020)
Turning the corner on therapeutic cancer vaccines
Robert E. Hollingsworth et al.
NPJ VACCINES (2019)
Optimizing T-cell receptor avidity with somatic hypermutation
David Bassan et al.
INTERNATIONAL JOURNAL OF CANCER (2019)
Neoantigen vaccine: an emerging tumor immunotherapy
Miao Peng et al.
MOLECULAR CANCER (2019)
Mathematical modelling of cancer stem cell-targeted immunotherapy
Daniel Sigal et al.
MATHEMATICAL BIOSCIENCES (2019)
Defining 'T cell exhaustion'
Christian U. Blank et al.
NATURE REVIEWS IMMUNOLOGY (2019)
CD8 T Cell Exhaustion in Chronic Infection and Cancer: Opportunities for Interventions
Masao Hashimoto et al.
ANNUAL REVIEW OF MEDICINE, VOL 69 (2018)
The Union between Structural and Practical Identifiability Makes Strength in Reducing Oncological Model Complexity: A Case Study
Maria Pia Saccomani et al.
COMPLEXITY (2018)
CAR T cell immunotherapy for human cancer
Carl H. June et al.
SCIENCE (2018)
Talimogene laherparepvec: First in class oncolytic virotherapy
Robert M. Conry et al.
HUMAN VACCINES & IMMUNOTHERAPEUTICS (2018)
Interferon-Gamma at the Crossroads of Tumor Immune Surveillance or Evasion
Flavia Castro et al.
FRONTIERS IN IMMUNOLOGY (2018)
Developing a Minimally Structured Mathematical Model of Cancer Treatment with Oncolytic Viruses and Dendritic Cell Injections
Jana L. Gevertz et al.
COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE (2018)
From discovery to licensure, the Adjuvant System story
Nathalie Garcon et al.
HUMAN VACCINES & IMMUNOTHERAPEUTICS (2017)
Dendritic cell and antigen dispersal landscapes regulate T cell immunity
Michael Y. Gerner et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2017)
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
Ugur Sahin et al.
NATURE (2017)
An immunogenic personal neoantigen vaccine for patients with melanoma
Patrick A. Ott et al.
NATURE (2017)
Combination therapy of cancer with cancer vaccine and immune checkpoint inhibitors: A mathematical model
Xiulan Lai et al.
PLOS ONE (2017)
Periodically Pulsed Immunotherapy in a Mathematical Model of Tumor, CD4+ T Cells, and Antitumor Cytokine Interactions
Hsiu-Chuan Wei et al.
COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE (2017)
Cancer vaccines in the era of checkpoint blockade: the magic is in the adjuvant
Willem W. Overwijk
CURRENT OPINION IN IMMUNOLOGY (2017)
'Final common pathway' of human cancer immunotherapy: targeting random somatic mutations
Eric Tran et al.
NATURE IMMUNOLOGY (2017)
Human immune system variation
Petter Brodin et al.
NATURE REVIEWS IMMUNOLOGY (2017)
Avidity characterization of genetically engineered T-cells with novel and established approaches
Victoria Hillerdal et al.
BMC IMMUNOLOGY (2016)
Model calibration and uncertainty analysis in signaling networks
Tim Heinemann et al.
CURRENT OPINION IN BIOTECHNOLOGY (2016)
Dendritic Cells and Cancer Immunity
Alycia Gardner et al.
TRENDS IN IMMUNOLOGY (2016)
Structural Identifiability of Dynamic Systems Biology Models
Alejandro F. Villaverde et al.
PLOS COMPUTATIONAL BIOLOGY (2016)
TCR affinity for p/MHC formed by tumor antigens that are self-proteins: impact on efficacy and toxicity
Jennifer D. Stone et al.
CURRENT OPINION IN IMMUNOLOGY (2015)
Summary of the DREAM8 Parameter Estimation Challenge: Toward Parameter Identification for Whole-Cell Models
Jonathan R. Karr et al.
PLOS COMPUTATIONAL BIOLOGY (2015)
COSMIC: exploring the world's knowledge of somatic mutations in human cancer
Simon A. Forbes et al.
NUCLEIC ACIDS RESEARCH (2015)
Comorbidity Assessment in Skin Cancer Patients: A Pilot Study Comparing Medical Interview with a Patient-Reported Questionnaire
Erica H. Lee et al.
JOURNAL OF SKIN CANCER (2015)
High Avidity CD8+ T Cells Efficiently Eliminate Motile HIV-Infected Targets and Execute a Locally Focused Program of Anti-Viral Function
Maria Hottelet Foley et al.
PLOS ONE (2014)
Antigen-Specific Inhibition of High-Avidity T Cell Target Lysis by Low-Avidity T Cells via Trogocytosis
Brile Chung et al.
CELL REPORTS (2014)
Comparison of Vaccine-Induced Effector CD8 T Cell Responses Directed against Self- and Non-Self-Tumor Antigens: Implications for Cancer Immunotherapy
Sara R. Pedersen et al.
JOURNAL OF IMMUNOLOGY (2013)
Quantifying T lymphocyte turnover
Rob J. De Boer et al.
JOURNAL OF THEORETICAL BIOLOGY (2013)
T Cell Activation is Determined by the Number of Presented Antigens
Janosch Deeg et al.
NANO LETTERS (2013)
Persistent antigen at vaccination sites induces tumor-specific CD8+ T cell sequestration, dysfunction and deletion
Yared Hailemichael et al.
NATURE MEDICINE (2013)
Personalized medicine in oncology: where have we come from and where are we going?
Fabrice Andre et al.
PHARMACOGENOMICS (2013)
Molecular mechanisms of T cell co-stimulation and co-inhibition
Lieping Chen et al.
NATURE REVIEWS IMMUNOLOGY (2013)
A Mathematical Model of the Enhancement of Tumor Vaccine Efficacy by Immunotherapy
Shelby Wilson et al.
BULLETIN OF MATHEMATICAL BIOLOGY (2012)
Functional Avidity: A Measure to Predict the Efficacy of Effector T Cells?
Selena Vigano et al.
CLINICAL & DEVELOPMENTAL IMMUNOLOGY (2012)
Peptide-MHC class I stability is a better predictor than peptide affinity of CTL immunogenicity
Mikkel Harndahl et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2012)
Autocrine IFN-γ Promotes Naive CD8 T Cell Differentiation and Synergizes with IFN-α To Stimulate Strong Function
Julie M. Curtsinger et al.
JOURNAL OF IMMUNOLOGY (2012)
Alternative to Ritt's pseudodivision for finding the input-output equations of multi-output models
Nicolette Meshkat et al.
MATHEMATICAL BIOSCIENCES (2012)
Sipuleucel-T: harbinger of a new age of therapeutics for prostate cancer
Ravi A. Madan et al.
EXPERT REVIEW OF VACCINES (2011)
Repeated PR1 and WT1 peptide vaccination in Montanide-adjuvant fails to induce sustained high-avidity, epitope-specific CD8+ T cells in myeloid malignancies
Katayoun Rezvani et al.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2011)
Sensitivity analysis approaches applied to systems biology models
Z. Zi
IET SYSTEMS BIOLOGY (2011)
Importance of MUC1 and spontaneous mouse tumor models for understanding the immunobiology of human adenocarcinomas
Olivera J. Finn et al.
IMMUNOLOGIC RESEARCH (2011)
Finding identifiable parameter combinations in nonlinear ODE models and the rational reparameterization of their input-output equations
Nicolette Meshkat et al.
MATHEMATICAL BIOSCIENCES (2011)
gp100 Peptide Vaccine and Interleukin-2 in Patients with Advanced Melanoma
Douglas J. Schwartzentruber et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
T-cell triggering thresholds are modulated by the number of antigen within individual T-cell receptor clusters
Boryana N. Manza et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Vaccine Adjuvants: Putting Innate Immunity to Work
Robert L. Coffman et al.
IMMUNITY (2010)
Predicting Outcomes of Prostate Cancer Immunotherapy by Personalized Mathematical Models
Natalie Kronik et al.
PLOS ONE (2010)
Mature dendritic cells use endocytic receptors to capture and present antigens
Craig D. Platt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Concurrent Trastuzumab and HER2/neu-Specific Vaccination in Patients With Metastatic Breast Cancer
Mary L. Disis et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
On immunotherapies and cancer vaccination protocols: A mathematical modelling approach
Badal Joshi et al.
JOURNAL OF THEORETICAL BIOLOGY (2009)
An algorithm for finding globally identifiable parameter combinations of nonlinear ODE models using Grobner Bases
Nicolette Meshkat et al.
MATHEMATICAL BIOSCIENCES (2009)
Optimal Experimental Design for Parameter Estimation of a Cell Signaling Model
Samuel Bandara et al.
PLOS COMPUTATIONAL BIOLOGY (2009)
Selection of high-avidity CD8 T cells correlates with control of hepatitis C virus infection
Berangere Neveu et al.
HEPATOLOGY (2008)
Three phase II cytokine working group trials of gp100 (210M) peptide plus high-dose interleukin-2 in patients with HLA-A2-positive advanced melanoma
Jeffrey A. Sosman et al.
JOURNAL OF CLINICAL ONCOLOGY (2008)
Cutting edize: Dendritic cells prime a high avidity CTL response independent of the level of presented antigen
Charles J. Kroger et al.
JOURNAL OF IMMUNOLOGY (2008)
DAISY:: A new software tool to test global identifiability of biological and physiological systems
Giuseppina Bellu et al.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE (2007)
Cutting edge:: CD8+ T cell clones possess the potential to differentiate into both high- and low-avidity effector cells
Charles J. Kroger et al.
JOURNAL OF IMMUNOLOGY (2007)
The value of innovation: the economics of targeted drugs for cancer
Cara C. Tigue et al.
TARGETED ONCOLOGY (2007)
T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster
Rajat Varma et al.
IMMUNITY (2006)
Diversity and recognition efficiency of T cell responses to cancer
TB Stuge et al.
PLOS MEDICINE (2004)
Different dynamics of CD4+ and CD8+ T cell responses during and after acute lymphocytic choriomeningitis virus infection
RJ De Boer et al.
JOURNAL OF IMMUNOLOGY (2003)
Presentation of exogenous antigens on major histocompatibility complex (MHC) class I and MHC class II molecules is differentially regulated during dendritic cell maturation
L Delamarre et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Adjuvant immunization of HLA-A2-positive melanoma patients with a modified gp100 peptide induces peptide-specific CD8+ T-cell responses
JW Smith et al.
JOURNAL OF CLINICAL ONCOLOGY (2003)
Chronic myelogenous leukemia shapes host immunity by selective deletion of high-avidity leukemia-speciflic T cells
JJ Molldrem et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Antigen density presented by dendritic cells in vivo differentially affects the number and avidity of primary, memory, and recall CD8+ T cells
TNJ Bullock et al.
JOURNAL OF IMMUNOLOGY (2003)
T cells down-modulate peptide-MHC complexes on APCs in vivo
RM Kedl et al.
NATURE IMMUNOLOGY (2002)
Strategies for designing and optimizing new generation vaccines
JA Berzofsky et al.
NATURE REVIEWS IMMUNOLOGY (2001)
Manipulation of avidity to improve effectiveness of adoptively transferred CD8+ T cells for melanoma immunotherapy in human MHC class I-transgenic mice
TNJ Bullock et al.
JOURNAL OF IMMUNOLOGY (2001)
Peptide requirement for CTL activation reflects the sensitivity to CD3 engagement:: Correlation with CD8αβ versus CD8αα expression
AG Cawthon et al.
JOURNAL OF IMMUNOLOGY (2001)
Cancer vaccines
RF Rousseau et al.
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA (2001)
Naive CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation
MJB van Stipdonk et al.
NATURE IMMUNOLOGY (2001)