Related references
Note: Only part of the references are listed.Nicotine exposure potentiates lung tumorigenesis by perturbing cellular surveillance
Qiang Zhang et al.
BRITISH JOURNAL OF CANCER (2020)
Cancer statistics, 2020
Rebecca L. Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2020)
A light-triggered self-reinforced nanoagent for targeted chemo-photodynamic therapy of breast cancer bone metastases via ER stress and mitochondria mediated apoptotic pathways
Yanjuan Huang et al.
JOURNAL OF CONTROLLED RELEASE (2020)
Cell surface GRP78 promotes stemness in normal and neoplastic cells
Clay Conner et al.
SCIENTIFIC REPORTS (2020)
GALNT6 promotes invasion and metastasis of human lung adenocarcinoma cells through O-glycosylating chaperone protein GRP78
Jing Song et al.
CELL DEATH & DISEASE (2020)
Omega-3 Fatty Acid-Enriched Fish Oil and Selenium Combination Modulates Endoplasmic Reticulum Stress Response Elements and Reverses Acquired Gefitinib Resistance in HCC827 Lung Adenocarcinoma Cells
Chien-Huang Liao et al.
MARINE DRUGS (2020)
Inhibition of the hexosamine biosynthesis pathway potentiates cisplatin cytotoxicity by decreasing BiP expression in non-small-cell lung cancer cells
Wenshu Chen et al.
MOLECULAR CARCINOGENESIS (2019)
ER stress sensor, glucose regulatory protein 78 (GRP78) regulates redox status in pancreatic cancer thereby maintaining stemness
Patricia Dauer et al.
CELL DEATH & DISEASE (2019)
Glucose-Regulated Protein 78 Signaling Regulates Hypoxia-Induced Epithelial-Mesenchymal Transition in A549 Cells
Ling-Ling Sun et al.
FRONTIERS IN ONCOLOGY (2019)
The deubiquitylase OTUD3 stabilizes GRP78 and promotes lung tumorigenesis
Tongde Du et al.
NATURE COMMUNICATIONS (2019)
Cancer-associated fibroblasts: an emerging target of anti-cancer immunotherapy
Tongyan Liu et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)
Inhibiting lysine 353 oxidation of GRP78 by a hypochlorous probe targeting endoplasmic reticulum promotes autophagy in cancer cells
Junya Ning et al.
CELL DEATH & DISEASE (2019)
Anti-tumor effects and mechanism of GA-13315, a novel gibberellin derivative, in human lung adenocarcinoma: an in vitro and in vivo study
Lin Xie et al.
CELLULAR & MOLECULAR BIOLOGY LETTERS (2019)
Global Epidemiology of Lung Cancer
Julie A. Barta et al.
ANNALS OF GLOBAL HEALTH (2019)
Endoplasmic reticulum stress-mediated autophagy protects against β,β-dimethylacrylshikonin-induced apoptosis in lung adenocarcinoma cells
Haibing Wang et al.
CANCER SCIENCE (2018)
Sepia Ink Oligopeptide Induces Apoptosis of Lung Cancer Cells via Mitochondrial Pathway
Xiaohua Wang et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)
Inhibitory Effect of Kurarinone on Growth of Human Non-small Cell Lung Cancer: An Experimental Study Both in Vitro and in Vivo Studies
Jie Yang et al.
FRONTIERS IN PHARMACOLOGY (2018)
Antibody Targeting GRP78 Enhances the Efficacy of Radiation Therapy in Human Glioblastoma and Non-Small Cell Lung Cancer Cell Lines and Tumor Models
David Y. A. Dadey et al.
CLINICAL CANCER RESEARCH (2017)
Role of Autophagy and Apoptosis in Non-Small-Cell Lung Cancer
Guangbo Liu et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
The oxido-metabolic driver ATF4 enhances temozolamide chemo-resistance in human gliomas
Daishi Chen et al.
ONCOTARGET (2017)
被撤回的出版物: Endoplasmic Reticulum Stress Promotes Autophagy and Apoptosis and Reduces Chemotherapy Resistance in Mutant p53 Lung Cancer Cells (Retracted article. See vol. 55, pg. 239, 2021)
Ping-Ping Gan et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2017)
Mitochondrial ATAD3A combines with GRP78 to regulate the WASF3 metastasis-promoting protein
Y. Teng et al.
ONCOGENE (2016)
IRE1α-TRAF2-ASK1 pathway is involved in CSTMP-induced apoptosis and ER stress in human non-small cell lung cancer A549 cells
Jiexia Zhang et al.
BIOMEDICINE & PHARMACOTHERAPY (2016)
Cancer Statistics, 2016
Rebecca L. Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2016)
Inhibition of autophagy with chloroquine potentiates carfilzomib-induced apoptosis in myeloma cells in vitro and in vivo
Vidal Jarauta et al.
CANCER LETTERS (2016)
Endoplasmic reticulum stress induces 5-fluorouracil resistance in human colon cancer cells
Joon Ki Kim et al.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2016)
Autophagy inhibition facilitates erlotinib cytotoxicity in lung cancer cells through modulation of endoplasmic reticulum stress
Zhongliang Wang et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2016)
Tumor-Specific Binding of Radiolabeled PEGylated GIRLRG Peptide: A Novel Agent for Targeting Cancers
Vaishali Kapoor et al.
JOURNAL OF NUCLEAR MEDICINE (2016)
Cancer-associated fibroblasts promote non-small cell lung cancer cell invasion by upregulation of glucose-regulated protein 78 (GRP78) expression in an integrated bionic microfluidic device
Ting Yu et al.
ONCOTARGET (2016)
Activation of endoplasmic reticulum stress is involved in the activity of icariin against human lung adenocarcinoma cells
Shouyin Di et al.
APOPTOSIS (2015)
High Expression of GRP78 Promotes Invasion and Metastases in Patients with Esophageal Squamous Cell Carcinoma
Guohong Zhao et al.
DIGESTIVE DISEASES AND SCIENCES (2015)
Serum GRP78 as a Tumor Marker and Its Prognostic Significance in Non-Small Cell Lung Cancers: A Retrospective Study
Xiao Ma et al.
DISEASE MARKERS (2015)
Acid-induced autophagy protects human lung cancer cells from apoptosis by activating ER stress
Wen-Yue Xie et al.
EXPERIMENTAL CELL RESEARCH (2015)
Overexpressed GRP78 affects EMT and cell-matrix adhesion via autocrine TGF-β/Smad2/3 signaling
Lichao Zhang et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2015)
Treatment approaches for EGFR-inhibitor-resistant patients with non-small-cell lung cancer
Chee-Seng Tan et al.
LANCET ONCOLOGY (2015)
EGFR inhibitor and chemotherapy combinations for acquired TKI resistance in EGFR-mutant NSCLC models
Niina Laurila et al.
MEDICAL ONCOLOGY (2015)
Sanguinarine-induced apoptosis in lung adenocarcinoma cells is dependent on reactive oxygen species production and endoplasmic reticulum stress
Shuang Gu et al.
ONCOLOGY REPORTS (2015)
Cancer-Associated Fibroblasts: Their Characteristics and Their Roles in Tumor Growth
Kazuyoshi Shiga et al.
CANCERS (2015)
Glucose-regulated protein 78 (GRP78) regulates colon cancer metastasis through EMT biomarkers and the NRF-2/HO-1 pathway
Yu-Jia Chang et al.
TUMOR BIOLOGY (2015)
Modulation of endoplasmic reticulum (ER) stress-induced autophagy by C/EBP homologous protein (CHOP) and inositol-requiring enzyme 1α (IRE1α) in human colon cancer cells
Yosuke Shimodaira et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
Allosteric Inhibition of the IRE1α RNase Preserves Cell Viability and Function during Endoplasmic Reticulum Stress
Rajarshi Ghosh et al.
CELL (2014)
Atomistic Autophagy: The Structures of Cellular Self-Digestion
James H. Hurley et al.
CELL (2014)
Continual Exposure to Cigarette Smoke Extracts Induces Tumor-Like Transformation of Human Nontumor Bronchial Epithelial Cells in a Microfluidic Chip
Encheng Li et al.
JOURNAL OF THORACIC ONCOLOGY (2014)
The multifaceted role of the embryonic gene Cripto-1 in cancer, stem cells and epithelial-mesenchymal transition
Malgorzata Klauzinska et al.
SEMINARS IN CANCER BIOLOGY (2014)
Phosphoregulation of Ire1 RNase splicing activity
Filippo Prischi et al.
NATURE COMMUNICATIONS (2014)
Autophagy Is Required for Glucose Homeostasis and Lung Tumor Maintenance
Gizem Karsli-Uzunbas et al.
CANCER DISCOVERY (2014)
Ire1 Has Distinct Catalytic Mechanisms for XBP1/HAC1 Splicing and RIDD
Arvin B. Tam et al.
CELL REPORTS (2014)
Glucose-regulated proteins in cancer: molecular mechanisms and therapeutic potential
Amy S. Lee
NATURE REVIEWS CANCER (2014)
GRP78 secreted by tumor cells stimulates differentiation of bone marrow mesenchymal stem cells to cancer-associated fibroblasts
Yanan Peng et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
ER stress-induced cell death mechanisms
Renata Sano et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
Cigarette smoking affects oxidative protein folding in endoplasmic reticulum by modifying protein disulfide isomerase
Harshavardhan Kenche et al.
FASEB JOURNAL (2013)
Eeyarestatin causes cervical cancer cell sensitization to bortezomib treatment by augmenting ER stress and CHOP expression
German J. Brem et al.
GYNECOLOGIC ONCOLOGY (2013)
Cell-surface GRP78 facilitates colorectal cancer cell migration and invasion
Zongwei Li et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2013)
Synthetic studies of the spirocyclic cyclohexene part of versipelostatin, a novel GRP78/Bip molecular chaperone downregulator
Shu Sasaki et al.
JOURNAL OF ANTIBIOTICS (2013)
Targeting the unfolded protein response in disease
Claudio Hetz et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
Endoplasmic reticulum ribosome-binding protein 1 (RRBP1) overexpression is frequently found in lung cancer patients and alleviates intracellular stress-induced apoptosis through the enhancement of GRP78
H-Y Tsai et al.
ONCOGENE (2013)
GRP78-targeting subtilase cytotoxin sensitizes cancer cells to photodynamic therapy
M. Firczuk et al.
CELL DEATH & DISEASE (2013)
Autophagy Sustains Mitochondrial Glutamine Metabolism and Growth of BrafV600E-Driven Lung Tumors
Anne M. Strohecker et al.
CANCER DISCOVERY (2013)
The Cell Surface GRP78 Facilitates the Invasion of Hepatocellular Carcinoma Cells
Xiu-Xiu Zhang et al.
BIOMED RESEARCH INTERNATIONAL (2013)
Cancer drug resistance: an evolving paradigm
Caitriona Holohan et al.
NATURE REVIEWS CANCER (2013)
Glucose-Regulated Protein 78 Controls Cross-talk between Apoptosis and Autophagy to Determine Antiestrogen Responsiveness
Katherine L. Cook et al.
CANCER RESEARCH (2012)
An Intronic Polymorphism in GRP78 Improves Chemotherapeutic Prediction in Non-small Cell Lung Cancer
Xiao Zhu et al.
CHEST (2012)
Expression of ER stress and autophagy-related molecules in human non-small cell lung cancer and premalignant lesions
Kyoung Min Kim et al.
INTERNATIONAL JOURNAL OF CANCER (2012)
Impairment of the Ubiquitin-Proteasome Pathway by Methyl N-(6-Phenylsulfanyl-1H-benzimidazol-2-yl)carbamate Leads to a Potent Cytotoxic Effect in Tumor Cells A NOVEL ANTIPROLIFERATIVE AGENT WITH A POTENTIAL THERAPEUTIC IMPLICATION
Nilambra Dogra et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Expressions of GRP78 and Bax associate with differentiation, metastasis, and apoptosis in non-small cell lung cancer
Qing Sun et al.
MOLECULAR BIOLOGY REPORTS (2012)
Loss of the Oxidative Stress Sensor NPGPx Compromises GRP78 Chaperone Activity and Induces Systemic Disease
Pei-Chi Wei et al.
MOLECULAR CELL (2012)
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
Claudio Hetz
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
A Peptidic Unconjugated GRP78/BiP Ligand Modulates the Unfolded Protein Response and Induces Prostate Cancer Cell Death
Danilo Maddalo et al.
PLOS ONE (2012)
Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting
Min Ni et al.
BIOCHEMICAL JOURNAL (2011)
A Critical Role for GRP78/BiP in the Tumor Microenvironment for Neovascularization during Tumor Growth and Metastasis
Dezheng Dong et al.
CANCER RESEARCH (2011)
The Cell Biology of the Unfolded Protein Response
J. Alan Diehl et al.
GASTROENTEROLOGY (2011)
Unfolded protein response in cancer: the Physician's perspective
Xuemei Li et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2011)
The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress
Brian F. Teske et al.
MOLECULAR BIOLOGY OF THE CELL (2011)
Akt is the downstream target of GRP78 in mediating cisplatin resistance in ER stress-tolerant human lung cancer cells
Yidan Lin et al.
LUNG CANCER (2011)
Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress
Ira Tabas et al.
NATURE CELL BIOLOGY (2011)
Targeted Nanoparticles That Deliver a Sustained, Specific Release of Paclitaxel to Irradiated Tumors
Ralph J. Passarella et al.
CANCER RESEARCH (2010)
Novel Metastasis-Related Gene CIM Functions in the Regulation of Multiple Cellular Stress-Response Pathways
Kiyoshi Yanagisawa et al.
CANCER RESEARCH (2010)
Cell Surface Relocalization of the Endoplasmic Reticulum Chaperone and Unfolded Protein Response Regulator GRP78/BiP
Yi Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin
Markus Sallman Almen et al.
BMC BIOLOGY (2009)
Plasminogen Kringle 5 Induces Apoptosis of Brain Microvessel Endothelial Cells: Sensitization by Radiation and Requirement for GRP78 and LRP1
Braden C. McFarland et al.
CANCER RESEARCH (2009)
Role of ATF4 in regulation of autophagy and resistance to drugs and hypoxia
Tomasz Rzymski et al.
CELL CYCLE (2009)
Regulated Ire1-dependent decay of messenger RNAs in mammalian cells
Julie Hollien et al.
JOURNAL OF CELL BIOLOGY (2009)
Blockade of GRP78 sensitizes breast cancer cells to microtubules-interfering agents that induce the unfolded protein response
Jiao Wang et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2009)
Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells
Maria Salazar et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Regulation of PERK Signaling and Leukemic Cell Survival by a Novel Cytosolic Isoform of the UPR Regulator GRP78/BiP
Min Ni et al.
PLOS ONE (2009)
XBP-1 regulates angiogenesis in human pancreatic adenocarcinomas
Lorenzo Romero-Ramirez et al.
TRANSLATIONAL ONCOLOGY (2009)
A cell-penetrating peptidic GRP78 ligand for tumor cell-specific prodrug therapy
Yoshiyuki Yoneda et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor anglogenesis in transgene-induced mammary tumor development
Dezheng Dong et al.
CANCER RESEARCH (2008)
GRP78 and Raf-1 cooperatively confer resistance to endoplasmic reticulum stress-induced apoptosis
Chih-Wen Shu et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2008)
Glucose-regulated protein 78 regulates multiple malignant phenotypes in head and neck cancer and may serve as a molecular target of therapeutic intervention
Ching-Chi Chiu et al.
MOLECULAR CANCER THERAPEUTICS (2008)
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities
Inki Kim et al.
NATURE REVIEWS DRUG DISCOVERY (2008)
The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas
Peter Pyrko et al.
CANCER RESEARCH (2007)
PERK-dependent compartmentalization of ERAD and unfolded protein response machineries during ER stress
Maria Kondratyev et al.
EXPERIMENTAL CELL RESEARCH (2007)
IRE1 signaling is essential for ischemia-induced vascular endothelial growth factor-a expression and contributes to angiogenesis and tumor growth in vivo
Benjamin Drogat et al.
CANCER RESEARCH (2007)
GRP78 induction in cancer: Therapeutic and prognostic implications
Amy S. Lee
CANCER RESEARCH (2007)
Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response
Sebastian Bernales et al.
PLOS BIOLOGY (2006)
Autophagy is activated for cell survival after endoplasmic reticulum stress
Maiko Ogata et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Endoplasmic reticulum stress triggers autophagy
Tomohiro Yorimitsu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP
Adrienne W. Paton et al.
NATURE (2006)
(-)-epigallocatechin gallate overcomes resistance to etoposide-induced cell death by targeting the molecular chaperone glucose-regulated protein 78
Svetlana P. Ermakova et al.
CANCER RESEARCH (2006)
Targeting heat shock proteins on cancer cells: Selection, characterization, and cell-penetrating properties of a peptidic GRP78 ligand
Youngsoo Kim et al.
BIOCHEMISTRY (2006)
Glucose regulated proteins in cancer progression, drug resistance and immunotherapy
Yong Fu et al.
CANCER BIOLOGY & THERAPY (2006)
Localization of GRP78 to mitochondria under the unfolded protein response
Fang-Chun Sun et al.
BIOCHEMICAL JOURNAL (2006)
From acute ER stress to physiological roles of the Unfolded Protein Response
J Wu et al.
CELL DEATH AND DIFFERENTIATION (2006)
Coordination of ER and oxidative stress signaling: The PERK/Nrf2 signaling pathway
SB Cullinan et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2006)
Expression of endoplasmic reticulum molecular chaperone Grp78 in human lung cancer and its clinical significance
H Uramoto et al.
LUNG CANCER (2005)
Vascular targeting and antiangiogenesis agents induce drug resistance effector GRP78 within the tumor microenvironment
DZ Dong et al.
CANCER RESEARCH (2005)
Kringle 5 of human plasminogen induces apoptosis of endothelial and tumor cells through surface-expressed glucose-regulated protein 78
DJ Davidson et al.
CANCER RESEARCH (2005)
Overexpression of endoplasmic reticulum molecular chaperone GRP94 and GRP78 in human lung cancer tissues and its significance
Q Wang et al.
CANCER DETECTION AND PREVENTION (2005)
Effect on tumor cells of blocking survival response to glucose deprivation
HR Park et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2004)
Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligands
MA Arap et al.
CANCER CELL (2004)
Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors - Role of ATP binding site in suppression of caspase-7 activation
RK Reddy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of golgi localization signals
JS Shen et al.
DEVELOPMENTAL CELL (2002)
The glucose-regulated proteins: stress induction and clinical applications
AS Lee
TRENDS IN BIOCHEMICAL SCIENCES (2001)
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
F Urano et al.
SCIENCE (2000)