Journal
EUROPEAN JOURNAL OF IMMUNOLOGY
Volume 46, Issue 7, Pages 1574-1582Publisher
WILEY
DOI: 10.1002/eji.201546176
Keywords
Cancer; Chronic infection; Metabolism; Negative regulatory receptors; T cells
Categories
Funding
- TELEVIE [7.4512.13, 7.4535.12]
- Interuniversity Attraction Poles (BELSPO) [P7/39]
Ask authors/readers for more resources
T-cell metabolism is central to the shaping of a successful immune response. However, there are pathological situations where T cells are rendered dysfunctional and incapable of eliminating infected or transformed cells. Here, we review the current knowledge on T-cell metabolism and how persistent antigenic stimulation, in the form of cancer and chronic viral infection, modifies both metabolic and functional pathways in T cells.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available