4.6 Review

The role of mitochondria in metabolic disease: a special emphasis on heart dysfunction

Related references

Note: Only part of the references are listed.
Review Pathology

Mitochondrial Dynamics and Its Involvement in Disease

David C. Chan

ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 15, 2020 (2020)

Article Multidisciplinary Sciences

Red fluorescent CEPIA indicators for visualization of Ca2+ dynamics in mitochondria

Kazunori Kanemaru et al.

SCIENTIFIC REPORTS (2020)

Article Cardiac & Cardiovascular Systems

A 20/20 view of ANT function in mitochondrial biology and necrotic cell death

Michael J. Bround et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2020)

Article Cardiac & Cardiovascular Systems

Molecular nature and regulation of the mitochondrial permeability transition pore(s), drug target(s) in cardioprotection

Michela Carraro et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2020)

Article Cardiac & Cardiovascular Systems

ATP synthase c-subunit ring as the channel of mitochondrial permeability transition: Regulator of metabolism in development and degeneration

Nelli Mnatsakanyan et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2020)

Review Cardiac & Cardiovascular Systems

Multiple Levels of PGC-1α Dysregulation in Heart Failure

Shin-ichi Oka et al.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2020)

Article Biochemistry & Molecular Biology

Effects of resveratrol on regulation on UCP2 and cardiac function in diabetic rats

Jiayu Diao et al.

JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY (2019)

Article Biochemistry & Molecular Biology

SR-mitochondria communication in adult cardiomyocytes: A close relationship where the Ca2+ has a lot to say

Sergio De la Fuente et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2019)

Article Multidisciplinary Sciences

Mitochondrial Oxidative Phosphorylation defect in the Heart of Subjects with Coronary Artery Disease

Karima Ait-Aissa et al.

SCIENTIFIC REPORTS (2019)

Review Peripheral Vascular Disease

The Global Epidemic of the Metabolic Syndrome

Mohammad G. Saklayen

CURRENT HYPERTENSION REPORTS (2018)

Article Biochemistry & Molecular Biology

Stability of a type 2 diabetes rat model induced by high-fat diet feeding with low-dose streptozotocin injection

Xiao-xuan Guo et al.

JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B (2018)

Review Primary Health Care

Metabolic Syndrome Systems Thinking in Heart Disease

Ron Dommermuth et al.

PRIMARY CARE (2018)

Review Biochemistry & Molecular Biology

Targeting mitochondrial dysfunction and oxidative stress in heart failure: Challenges and opportunities

Ligia Akemi Kiyuna et al.

FREE RADICAL BIOLOGY AND MEDICINE (2018)

Article Peripheral Vascular Disease

Hyperglycemia activates the renin-angiotensin system and induces epithelial-mesenchymal transition in streptozotocin-induced diabetic kidneys

Chung-Ming Chen et al.

JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM (2018)

Review Biophysics

Mitochondrial Ca2+ and regulation of the permeability transition pore

Stephen Hurst et al.

JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2017)

Article Biochemistry & Molecular Biology

Hydrogen peroxide, nitric oxide and ATP are molecules involved in cardiac mitochondrial biogenesis in Diabetes

Silvina S. Bombicino et al.

FREE RADICAL BIOLOGY AND MEDICINE (2017)

Article Biochemistry & Molecular Biology

Reactive oxygen species production induced by pore opening in cardiac mitochondria: The role of complex III

Paavo Korge et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2017)

Review Neurosciences

Mitochondrial energetics and calcium coupling in the heart

Michael Kohlhaas et al.

JOURNAL OF PHYSIOLOGY-LONDON (2017)

Article Oncology

Metformin accelerates wound healing in type 2 diabetic db/db mice

Xue Han et al.

MOLECULAR MEDICINE REPORTS (2017)

Article Multidisciplinary Sciences

Increased mitochondrial nanotunneling activity, induced by calcium imbalance, affects intermitochondrial matrix exchanges

Manuela Lavorato et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Public, Environmental & Occupational Health

Metabolic Syndrome Prevalence by Race/Ethnicity and Sex in the United States, National Health and Nutrition Examination Survey, 1988-2012

Justin Xavier Moore et al.

PREVENTING CHRONIC DISEASE (2017)

Review Medicine, General & Internal

Diabetic cardiomyopathy: where we are and where we are going

Wang-Soo Lee et al.

KOREAN JOURNAL OF INTERNAL MEDICINE (2017)

Article Cardiac & Cardiovascular Systems

Diastolic dysfunction in prediabetic male rats: Role of mitochondrial oxidative stress

Gabor Koncsos et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2016)

Article Biochemistry & Molecular Biology

Therapeutic inhibition of mitochondrial reactive oxygen species with mito-TEMPO reduces diabetic cardiomyopathy

Rui Ni et al.

FREE RADICAL BIOLOGY AND MEDICINE (2016)

Article Biochemical Research Methods

Comparative Proteomics Reveals Dysregulated Mitochondrial O-GlcNAcylation in Diabetic Hearts

Junfeng Ma et al.

JOURNAL OF PROTEOME RESEARCH (2016)

Article Physiology

Glucose Transporters in Cardiac Metabolism and Hypertrophy

Dan Shao et al.

COMPREHENSIVE PHYSIOLOGY (2016)

Review Biochemistry & Molecular Biology

Mitochondrial Dynamics in Diabetic Cardiomyopathy

Chad A. Galloway et al.

ANTIOXIDANTS & REDOX SIGNALING (2015)

Article Cardiac & Cardiovascular Systems

Distinct mPTP activation mechanisms in ischaemia-reperfusion: contributions of Ca2+, ROS, pH, and inorganic polyphosphate

Lea K. Seidlmayer et al.

CARDIOVASCULAR RESEARCH (2015)

Review Cell Biology

Mitochondrial biogenesis and dynamics in the developing and diseased heart

Gerald W. Dorn et al.

GENES & DEVELOPMENT (2015)

Article Multidisciplinary Sciences

The mitochondrial uniporter controls fight or flight heart rate increases

Yuejin Wu et al.

NATURE COMMUNICATIONS (2015)

Article Cell Biology

Mitochondrial inefficiencies and anoxic ATP hydrolysis capacities in diabetic rat heart

Toan Pham et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2014)

Article Endocrinology & Metabolism

Rescue of cardiac leptin receptors in db/db mice prevents myocardial triglyceride accumulation

Michael E. Hall et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2014)

Article Cardiac & Cardiovascular Systems

Functional deficiencies of subsarcolemmal mitochondria in the type 2 diabetic human heart

Tara L. Croston et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2014)

Review Cardiac & Cardiovascular Systems

Physiological and structural differences in spatially distinct subpopulations of cardiac mitochondria: influence of cardiac pathologies

John M. Hollander et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2014)

Review Endocrinology & Metabolism

Sudden cardiac death and diabetes mellitus

I. Vasiliadis et al.

JOURNAL OF DIABETES AND ITS COMPLICATIONS (2014)

Review Cardiac & Cardiovascular Systems

Mitochondrial reactive oxygen species production and elimination

Alexander Nickel et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2014)

Review Physiology

MITOCHONDRIAL REACTIVE OXYGEN SPECIES (ROS) AND ROS-INDUCED ROS RELEASE

Dmitry B. Zorov et al.

PHYSIOLOGICAL REVIEWS (2014)

Article Cell Biology

Defective sarcoplasmic reticulum-mitochondria calcium exchange in aged mouse myocardium

C. Fernandez-Sanz et al.

CELL DEATH & DISEASE (2014)

Review Pharmacology & Pharmacy

Murine models for pharmacological studies of the metabolic syndrome

Lyne Fellmann et al.

PHARMACOLOGY & THERAPEUTICS (2013)

Article Medicine, General & Internal

Diabetes and hypertension: the bad companions

Ele Ferrannini et al.

LANCET (2012)

Article Multidisciplinary Sciences

Mitochondrial Ca2+ uptake contributes to buffering cytoplasmic Ca2+ peaks in cardiomyocytes

Ilaria Drago et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Cardiac & Cardiovascular Systems

Increased propensity for cell death in diabetic human heart is mediated by mitochondrial-dependent pathways

Ethan J. Anderson et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2011)

Article Biochemistry & Molecular Biology

MiD49 and MiD51, new components of the mitochondrial fission machinery

Catherine S. Palmer et al.

EMBO REPORTS (2011)

Review Biotechnology & Applied Microbiology

Rodent Models for Metabolic Syndrome Research

Sunil K. Panchal et al.

JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2011)

Article Multidisciplinary Sciences

Fructose Modulates Cardiomyocyte Excitation-Contraction Coupling and Ca2+ Handling In Vitro

Kimberley M. Mellor et al.

PLOS ONE (2011)

Article Cardiac & Cardiovascular Systems

Mitochondrial dysfunction in the type 2 diabetic heart is associated with alterations in spatially distinct mitochondrial proteomes

Erinne R. Dabkowski et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2010)

Article Cardiac & Cardiovascular Systems

Enhanced apoptotic propensity in diabetic cardiac mitochondria: influence of subcellular spatial location

Courtney L. Williamson et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2010)

Review Cell Biology

Mouse models of the metabolic syndrome

Anon J. Kennedy et al.

DISEASE MODELS & MECHANISMS (2010)

Review Genetics & Heredity

Mitochondrial fission and fusion and their roles in the heart

Lesley A. Kane et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2010)

Review Genetics & Heredity

Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease

Jun Ren et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2010)

Article Cardiac & Cardiovascular Systems

Cannabidiol Attenuates Cardiac Dysfunction, Oxidative Stress, Fibrosis, and Inflammatory and Cell Death Signaling Pathways in Diabetic Cardiomyopathy

Mohanraj Rajesh et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2010)

Article Endocrinology & Metabolism

Diabetic cardiomyopathy, causes and effects

Sihem Boudina et al.

REVIEWS IN ENDOCRINE & METABOLIC DISORDERS (2010)

Review Cell Biology

Energetic requirements and bioenergetic modulation of mitochondrial morphology and dynamics

Cecile Sauvanet et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2010)

Article Biochemistry & Molecular Biology

Changes in islet plasma membrane calcium-ATPase activity and isoform expression induced by insulin resistance

Maria E. Alzugaray et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2009)

Article Biophysics

Mitochondria and reperfusion injury of the heart-A holey death but not beyond salvation

Andrew P. Halestrap

JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2009)

Article Biochemistry & Molecular Biology

Calcium Elevation in Mitochondria Is the Main Ca2+ Requirement for Mitochondrial Permeability Transition Pore (mPTP) Opening

Heidi K. Baumgartner et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Review Cardiac & Cardiovascular Systems

Controlling metabolism and cell death: At the heart of mitochondrial calcium signalling

Marta Murgia et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2009)

Article Cardiac & Cardiovascular Systems

Mitochondrial free calcium regulation during sarcoplasmic reticulum calcium release in rat cardiac myocytes

Tatyana N. Andrienko et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2009)

Review Cardiac & Cardiovascular Systems

What is the mitochondrial permeability transition pore?

Andrew P. Halestrap

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2009)

Article Cardiac & Cardiovascular Systems

Substrate-Specific Derangements in Mitochondrial Metabolism and Redox Balance in the Atrium of the Type 2 Diabetic Human Heart

Ethan J. Anderson et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2009)

Article Multidisciplinary Sciences

Gene Remodeling in Type 2 Diabetic Cardiomyopathy and Its Phenotypic Rescue with SERCA2a

Ioannis Karakikes et al.

PLOS ONE (2009)

Article Biochemistry & Molecular Biology

Regulation of the Cardiac Muscle Ryanodine Receptor by O2 Tension and S-Nitrosoglutathione

Junhui Sun et al.

BIOCHEMISTRY (2008)

Review Cardiac & Cardiovascular Systems

Transcriptional control of mitochondrial biogenesis:: the central role of PGC-1α

Renee Ventura-Clapier et al.

CARDIOVASCULAR RESEARCH (2008)

Article Biochemistry & Molecular Biology

Superoxide flashes in single mitochondria

Wang Wang et al.

Article Multidisciplinary Sciences

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

Olga Martins de Brito et al.

NATURE (2008)

Article Multidisciplinary Sciences

Interferon-α initiates type 1 diabetes in nonobese diabetic mice

Qing Li et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Review Cardiac & Cardiovascular Systems

Defective mitochondrial biogenesis - A hallmark of the high cardiovascular risk in the metabolic syndrome?

Enzo Nisoli et al.

CIRCULATION RESEARCH (2007)

Review Medicine, General & Internal

Mechanisms of disease - The failing heart - An engine out of fuel

Stefan Neubauer

NEW ENGLAND JOURNAL OF MEDICINE (2007)

Article Biochemistry & Molecular Biology

Type 1 ryanodine receptor in cardiac mitochondria: Transducer of excitation-metabolism coupling

G Beutner et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2005)

Article Cardiac & Cardiovascular Systems

Cardiomyocyte apoptosis induced by short-term diabetes requires mitochondrial GSH depletion

S Ghosh et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2005)

Article Multidisciplinary Sciences

The mitochondrial calcium uniporter is a highly selective ion channel

Y Kirichok et al.

NATURE (2004)

Article Multidisciplinary Sciences

OPA1 requires mitofusin 1 to promote mitochondrial fusion

S Cipolat et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Endocrinology & Metabolism

Cardiac mitochondrial damage and biogenesis in a chronic model of type 1 diabetes

X Shen et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2004)

Review Cell Biology

Calcium, ATP, and ROS: a mitochondrial love-hate triangle

PS Brookes et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2004)

Article Endocrinology & Metabolism

Cardiac lipid accumulation associated with diastolic dysfunction in obese mice

C Christoffersen et al.

ENDOCRINOLOGY (2003)

Article Multidisciplinary Sciences

A transgenic model of visceral obesity and the metabolic syndrome

H Masuzaki et al.

SCIENCE (2001)

Article Biochemistry & Molecular Biology

The rapid mode of calcium uptake into heart mitochondria (RaM): comparison to RaM in liver mitochondria

L Buntinas et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2001)

Article Biochemistry & Molecular Biology

Selective targeting of a redox-active ubiquinone to mitochondria within cells - Antioxidant and antiapoptotic properties

GF Kelso et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Medicine, Research & Experimental

Peroxisome proliferator-activated receptor γ coactivator-1 promotes cardiac mitochondrial biogenesis

JJ Lehman et al.

JOURNAL OF CLINICAL INVESTIGATION (2000)