4.1 Article

Unilateral Obstructed Mullerian Anomalies: A Series of Unusual Variants of Known Anomalies

Journal

JOURNAL OF PEDIATRIC AND ADOLESCENT GYNECOLOGY
Volume 34, Issue 5, Pages 749-757

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.jpag.2021.04.005

Keywords

Mullerian anomalies; Unilateral obstruction; Pelvic pain; OHVIRA; Ectopic ureter; Adenomyosis; Hematometra; Hematocolpos; Endometriosis

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This article discusses three cases of unilateral Mullerian obstructions in adolescent female patients, highlighting the potential for unusual variations even among well-known Mullerian anomalies. The importance of correct diagnostic tools and individualized treatment plans for successful management of these conditions is emphasized.
Background: Obstructed Mullerian anomalies in adolescents can be grouped into complete outflow obstruction or unilateral outflow obstruction. The challenge with unilateral obstructions is that diagnosis can be delayed for weeks to years, as menstruation occurs normally through the patent side and thus obstruction is often not initially considered in the differential diagnosis. Cases: In this case series, we present 3 unusual and challenging cases of unilateral Mullerian obstructions in adolescent female patients, along with strategies for diagnosis and management. Each case involves a unique variation of a recognized Mullerian anomaly that was initially misdiagnosed, leading to a significant delay in definitive diagnosis and treatment. Summary and Conclusion: These cases highlight that even among the well-described Mullerian anomalies, there can be unusual variations. Patients who do not respond to initial management or who develop new symptoms should be further evaluated to confirm the correct diagnosis Tools that may be helpful in making the correct diagnosis include imaging studies that use contrast dye to better delineate cavities and their connections, magnetic resonance imaging with a radiologist experienced in Mullerian anomalies, and an examination under anesthesia. A definitive diagnosis is critical to the successful management of these conditions, and individualized management plans are required for each patient depending on their specific anomaly and their preferences for treatment.

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