Effect of temperature on the equilibrium solubility of dimethylolpropionic acid: Measurement, correlation, thermodynamic analysis and solvent selection

This paper focuses on the effect of temperature on the equilibrium solubility of dimethylolpropionic acid (DMPA) via a solid-liquid equilibrium method. In essence, the solubility of DMPA is a function of temperature. When temperature increases, molecular interactions between DMPA and solvent molecules are accelerated. Thereby, the solubility of DMPA is enhanced. It was found that the mole fraction solubility of DMPA in mono solvents from high to low is in the order: 1,4-dioxane > gamma-butyrolactone (GBL) > gamma-valerolactone (GVL) > methyl isobutyl ketone (MIBK) > ethylacetate > butylacetate > cyclopentyl methyl ether (CPME). The experimental solubility data are recorded and fit well with the Apelblat equation, Buchowski-Ksiazczak lambda h equation, the NRTL model and the Wilson model. Thermodynamic properties of DMPA are analyzed viz. Delta H-sol, Delta S-sol, Delta(mix)G, Delta H-mix and Delta S-mix. The polymorphic transitions of DMPA in the various solvents have been studied via differential scanning calorimetry (DSC). (C) 2021 Elsevier B.V. All rights reserved.

Automated summary

This paper investigates the effect of temperature on the equilibrium solubility of DMPA using a solid-liquid equilibrium method. The study shows that higher temperature enhances the solubility of DMPA by accelerating molecular interactions between DMPA and solvent molecules. Experimental results reveal the order of mole fraction solubility of DMPA in different solvents and analyze the thermodynamic properties and polymorphic transitions of DMPA.