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The immunomodulating role of exercise in metabolic disease
Graeme I. Lancaster et al.
TRENDS IN IMMUNOLOGY (2014)
Diet-induced obesity promotes myelopoiesis in hematopoietic stem cells
Kanakadurga Singer et al.
MOLECULAR METABOLISM (2014)
HIF-mediated innate immune responses: cell signaling and therapeutic implications
Alison J. Harris et al.
HYPOXIA (2014)
Short-term weight loss attenuates local tissue inflammation and improves insulin sensitivity without affecting adipose inflammation in obese mice
Dae Young Jung et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2013)
The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting
Miriam Merad et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 31 (2013)
Exercise training attenuates adipose tissue fibrosis in diet-induced obese mice
Noriaki Kawanishi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
Obesity Activates a Program of Lysosomal-Dependent Lipid Metabolism in Adipose Tissue Macrophages Independently of Classic Activation
Xiaoyuan Xu et al.
CELL METABOLISM (2013)
Hyperglycemia Promotes Myelopoiesis and Impairs the Resolution of Atherosclerosis
Prabhakara R. Nagareddy et al.
CELL METABOLISM (2013)
Imbalance between Neutrophil Elastase and its Inhibitor α1-Antitrypsin in Obesity Alters Insulin Sensitivity, Inflammation, and Energy Expenditure
Virginie Mansuy-Aubert et al.
CELL METABOLISM (2013)
Prolyl Hydroxylase Domain Protein 2 Plays a Critical Role in Diet-Induced Obesity and Glucose Intolerance
Hirohide Matsuura et al.
CIRCULATION (2013)
Multiple Adipose Depots Increase Cardiovascular Risk via Local and Systemic Effects
Kalypso Karastergiou et al.
CURRENT ATHEROSCLEROSIS REPORTS (2013)
Galectin-3 Deficiency Accelerates High-Fat Diet-Induced Obesity and Amplifies Inflammation in Adipose Tissue and Pancreatic Islets
Nada N. Pejnovic et al.
DIABETES (2013)
Induction of Cytosolic Phospholipase A2α Is Required for Adipose Neutrophil Infiltration and Hepatic Insulin Resistance Early in the Course of High-Fat Feeding
Nurit Hadad et al.
DIABETES (2013)
Roles of Chemokine Ligand-2 (CXCL2) and Neutrophils in Influencing Endothelial Cell Function and Inflammation of Human Adipose Tissue
Christine Rouault et al.
ENDOCRINOLOGY (2013)
Nine Months of Combined Training Improves Ex Vivo Skeletal Muscle Metabolism in Individuals With Type 2 Diabetes
Lauren M. Sparks et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2013)
Improved Hepatic Lipid Composition Following Short-Term Exercise in Nonalcoholic Fatty Liver Disease
Jacob M. Haus et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2013)
Direct control of hepatic glucose production by interleukin-13 in mice
Kristopher J. Stanya et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages
Ari B. Molofsky et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
Inflammasome-Mediated Secretion of IL-1β in Human Monocytes through TLR2 Activation; Modulation by Dietary Fatty Acids
Ryan G. Snodgrass et al.
JOURNAL OF IMMUNOLOGY (2013)
Cutting Edge: IL-25 Elicits Innate Lymphoid Type 2 and Type II NKT Cells That Regulate Obesity in Mice
Emily Hams et al.
JOURNAL OF IMMUNOLOGY (2013)
Myeloid cell HIF-1α regulates asthma airway resistance and eosinophil function
Laura E. Crotty Alexander et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2013)
Type 2 innate lymphoid cells control eosinophil homeostasis
Jesse C. Nussbaum et al.
NATURE (2013)
Succinate is an inflammatory signal that induces IL-1β through HIF-1α
G. M. Tannahill et al.
NATURE (2013)
Brown and beige fat: development, function and therapeutic potential
Matthew Harms et al.
NATURE MEDICINE (2013)
Tracking adipogenesis during white adipose tissue development, expansion and regeneration
Qiong A. Wang et al.
NATURE MEDICINE (2013)
Exercise Attenuates M1 Macrophages and CD8+ T Cells in the Adipose Tissue of Obese Mice
Noriaki Kawanishi et al.
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE (2013)
HYPOXIA AND ADIPOSE TISSUE FUNCTION AND DYSFUNCTION IN OBESITY
Paul Trayhurn
PHYSIOLOGICAL REVIEWS (2013)
The role of innate immune cells in obese adipose tissue inflammation and development of insulin resistance
Jindrich Chmelar et al.
THROMBOSIS AND HAEMOSTASIS (2013)
Metabolically healthy obesity: epidemiology, mechanisms, and clinical implications
Norbert Stefan et al.
LANCET DIABETES & ENDOCRINOLOGY (2013)
Beneficial effects of Brazilian propolis on type 2 diabetes in ob/ob mice Possible involvement of immune cells in mesenteric adipose tissue
Hiroshi Kitamura et al.
ADIPOCYTE (2013)
NASH and atherosclerosis are two aspects of a shared disease: Central role for macrophages
Veerle Bieghs et al.
ATHEROSCLEROSIS (2012)
Exercise training attenuates hepatic inflammation, fibrosis and macrophage infiltration during diet induced-obesity in mice
Noriaki Kawanishi et al.
BRAIN BEHAVIOR AND IMMUNITY (2012)
Hypoxia-Inducible Factors in Physiology and Medicine
Gregg L. Semenza
CELL (2012)
The Inflammasome Puts Obesity in the Danger Zone
Rinke Stienstra et al.
CELL METABOLISM (2012)
Zfp423 Expression Identifies Committed Preadipocytes and Localizes to Adipose Endothelial and Perivascular Cells
Rana K. Gupta et al.
CELL METABOLISM (2012)
CCR5 Plays a Critical Role in Obesity-Induced Adipose Tissue Inflammation and Insulin Resistance by Regulating Both Macrophage Recruitment and M1/M2 Status
Hironori Kitade et al.
DIABETES (2012)
Dendritic cells promote macrophage infiltration and comprise a substantial proportion of obesity-associated increases in CD11c+ cells in adipose tissue and liver
Maja Stefanovic-Racic et al.
DIABETES (2012)
Adipose Tissue Overexpression of Vascular Endothelial Growth Factor Protects Against Diet-Induced Obesity and Insulin Resistance
Ivet Elias et al.
DIABETES (2012)
Identification of adipose tissue dendritic cells correlated with obesity-associated insulin-resistance and inducing Th17 responses in mice and patients
Adeline Bertola et al.
DIABETES (2012)
Lymphocytes in obesity-related adipose tissue inflammation
A. Chatzigeorgiou et al.
DIABETOLOGIA (2012)
High frequency of activated natural killer and natural killer T-cells in patients with new onset of type 2 diabetes mellitus
Hui Guo et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2012)
Randomized trial of exercise effect on intrahepatic triglyceride content and lipid kinetics in nonalcoholic fatty liver disease
Shelby Sullivan et al.
HEPATOLOGY (2012)
Widespread Immunological Functions of Mast Cells: Fact or Fiction?
Hans-Reimer Rodewald et al.
IMMUNITY (2012)
Regulation of glucose/lipid metabolism and insulin sensitivity by interleukin-4
Y-H Chang et al.
INTERNATIONAL JOURNAL OF OBESITY (2012)
Mast Cells in Human Adipose Tissue: Link with Morbid Obesity, Inflammatory Status, and Diabetes
Adeline Divoux et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)
Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human
Atsuhiko Ichimura et al.
NATURE (2012)
Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase
Saswata Talukdar et al.
NATURE MEDICINE (2012)
Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance
Durba Pal et al.
NATURE MEDICINE (2012)
IgE and mast cells in allergic disease
Stephen J. Galli et al.
NATURE MEDICINE (2012)
The cellular and signaling networks linking the immune system and metabolism in disease
Olivia Osborn et al.
NATURE MEDICINE (2012)
Muscles, exercise and obesity: skeletal muscle as a secretory organ
Bente K. Pedersen et al.
NATURE REVIEWS ENDOCRINOLOGY (2012)
Dichotomous effects of VEGF-A on adipose tissue dysfunction
Kai Sun et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Obesity-induced endoplasmic reticulum stress causes chronic inflammation in adipose tissue
Noritaka Kawasaki et al.
SCIENTIFIC REPORTS (2012)
Lack of Exercise Is a Major Cause of Chronic Diseases
Frank W. Booth et al.
COMPREHENSIVE PHYSIOLOGY (2012)
Mast cells function as an alternative modulator of adipogenesis through 15-deoxy-delta-12, 14-prostaglandin J2
Akane Tanaka et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2011)
Increased Adipose Tissue Oxygen Tension in Obese Compared With Lean Men Is Accompanied by Insulin Resistance, Impaired Adipose Tissue Capillarization, and Inflammation
Gijs H. Goossens et al.
CIRCULATION (2011)
Lack of regular physical exercise or too much inactivity
John P. Thyfault et al.
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2011)
Differential Lipid Partitioning Between Adipocytes and Tissue Macrophages Modulates Macrophage Lipotoxicity and M2/M1 Polarization in Obese Mice
Xavier Prieur et al.
DIABETES (2011)
Eosinophils: multifaceted biological properties and roles in health and disease
Hirohito Kita
IMMUNOLOGICAL REVIEWS (2011)
Molecular Mechanism for Adiponectin-dependent M2 Macrophage Polarization LINK BETWEEN THE METABOLIC AND INNATE IMMUNE ACTIVITY OF FULL-LENGTH ADIPONECTIN
Palash Mandal et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Adipose Tissue Extracellular Matrix and Vascular Abnormalities in Obesity and Insulin Resistance
Michael Spencer et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2011)
Kruppel-like factor 4 regulates macrophage polarization
Xudong Liao et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Adipose tissue remodeling and obesity
Kai Sun et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis
Khoa D. Nguyen et al.
NATURE (2011)
The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling
Hergen Spits et al.
NATURE IMMUNOLOGY (2011)
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling
Haitao Wen et al.
NATURE IMMUNOLOGY (2011)
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
Bolormaa Vandanmagsar et al.
NATURE MEDICINE (2011)
Inflammasome is a central player in the induction of obesity and insulin resistance
Rinke Stienstra et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis
Davina Wu et al.
SCIENCE (2011)
Tissular Tregs: A unique population of adipose-tissue-resident Foxp3+CD4+T cells that impacts organismal metabolism
Daniela Cipolletta et al.
SEMINARS IN IMMUNOLOGY (2011)
Adipokines in inflammation and metabolic disease
Noriyuki Ouchi et al.
NATURE REVIEWS IMMUNOLOGY (2011)
The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease
Michael Gleeson et al.
NATURE REVIEWS IMMUNOLOGY (2011)
Adiponectin primes human monocytes into alternative anti-inflammatory M2 macrophages
Fina Lovren et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2010)
CCL5 Promotes Macrophage Recruitment and Survival in Human Adipose Tissue
Mayoura Keophiphath et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2010)
GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects
Da Young Oh et al.
CELL (2010)
Interleukin-6 Signaling in Liver-Parenchymal Cells Suppresses Hepatic Inflammation and Improves Systemic Insulin Action
F. Thomas Wunderlich et al.
CELL METABOLISM (2010)
The Inflammasome-Mediated Caspase-1 Activation Controls Adipocyte Differentiation and Insulin Sensitivity
Rinke Stienstra et al.
CELL METABOLISM (2010)
Pro-Inflammatory CD11c+CD206+ Adipose Tissue Macrophages Are Associated With Insulin Resistance in Human Obesity
John M. Wentworth et al.
DIABETES (2010)
Fibrosis in Human Adipose Tissue: Composition, Distribution, and Link With Lipid Metabolism and Fat Mass Loss
Adeline Divoux et al.
DIABETES (2010)
Differential activation and antagonistic function of HIF-α isoforms in macrophages are essential for NO homeostasis
Norihiko Takeda et al.
GENES & DEVELOPMENT (2010)
Adipose Tissue-specific Inhibition of Hypoxia-inducible Factor 1α Induces Obesity and Glucose Intolerance by Impeding Energy Expenditure in Mice
Xinmei Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
DGAT1-dependent triacylglycerol storage by macrophages protects mice from diet-induced insulin resistance and inflammation
Suneil K. Koliwad et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue
Aliki Kosteli et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Hypoxia-inducible factor 2α regulates macrophage function in mouse models of acute and tumor inflammation
Hongxia Z. Imtiyaz et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells
Kazuyo Moro et al.
NATURE (2010)
Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
Daniel R. Neill et al.
NATURE (2010)
IL25 elicits a multipotent progenitor cell population that promotes TH2 cytokine responses
Steven A. Saenz et al.
NATURE (2010)
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
Rongbin Zhou et al.
NATURE IMMUNOLOGY (2010)
IL-4/STAT6 immune axis regulates peripheral nutrient metabolism and insulin sensitivity
Roberto R. Ricardo-Gonzalez et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The NLRP3 Inflammasome: A Sensor for Metabolic Danger?
Kate Schroder et al.
SCIENCE (2010)
Adipose Tissue as a Dedicated Reservoir of Functional Mast Cell Progenitors
Sandrine Poglio et al.
STEM CELLS (2010)
Chemerin: at the crossroads of inflammation and obesity
Matthew C. Ernst et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2010)
Mast cell-orchestrated immunity to pathogens
Soman N. Abraham et al.
NATURE REVIEWS IMMUNOLOGY (2010)
The IL-1 family: regulators of immunity
John E. Sims et al.
NATURE REVIEWS IMMUNOLOGY (2010)
Effects of exercise and low-fat diet on adipose tissue inflammation and metabolic complications in obese mice
Victoria J. Vieira et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
Saturated Fatty Acids Do Not Directly Stimulate Toll-Like Receptor Signaling
Clett Erridge et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2009)
The Protein Kinase IKKε Regulates Energy Balance in Obese Mice
Shian-Huey Chiang et al.
CELL (2009)
Regulation of Angiogenesis by Oxygen and Metabolism
Peter Fraisl et al.
DEVELOPMENTAL CELL (2009)
Reduced Adipose Tissue Oxygenation in Human Obesity Evidence for Rarefaction, Macrophage Chemotaxis, and Inflammation Without an Angiogenic Response
Magdalena Pasarica et al.
DIABETES (2009)
Aerobic Exercise Training Reduces Hepatic and Visceral Lipids in Obese Individuals Without Weight Loss
Nathan A. Johnson et al.
HEPATOLOGY (2009)
Depot-specific differences in inflammatory mediators and a role for NK cells and IFN-γ in inflammation in human adipose tissue
R. W. O'Rourke et al.
INTERNATIONAL JOURNAL OF OBESITY (2009)
An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice
Brian C. Tieu et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4hi monocytes in obesity
Daniel J. Westcott et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Metabolic Dysregulation and Adipose Tissue Fibrosis: Role of Collagen VI
Tayeba Khan et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Hypoxia-Inducible Factor 1α Induces Fibrosis and Insulin Resistance in White Adipose Tissue
Nils Halberg et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice
Jian Liu et al.
NATURE MEDICINE (2009)
CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
Satoshi Nishimura et al.
NATURE MEDICINE (2009)
Brief Report: Functional Brown Adipose Tissue in Healthy Adults.
Kirsi A. Virtanen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Identification and Importance of Brown Adipose Tissue in Adult Humans.
Aaron M. Cypess et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Ablation of CD11c-Positive Cells Normalizes Insulin Sensitivity in Obese Insulin Resistant Animals
David Patsouris et al.
CELL METABOLISM (2008)
Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals
Guenther Boden et al.
DIABETES (2008)
Macrophage chemoattractant protein-1 deficiency fails to restrain macrophage infiltration into adipose tissue
Elizabeth A. Kirk et al.
DIABETES (2008)
Phenotypic Switching of Adipose Tissue Macrophages With Obesity Is Generated by Spatiotemporal Differences in Macrophage Subtypes
Carey N. Lumeng et al.
DIABETES (2008)
Impact of visceral adipose tissue on liver metabolism and insulin resistance. Part II: Visceral adipose tissue production and liver metabolism
J. Girard et al.
DIABETES & METABOLISM (2008)
In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue
Satoshi Nishimura et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Interleukin-10 is a protective factor against diet-induced insulin resistance in liver
Dennys E. Cintra et al.
JOURNAL OF HEPATOLOGY (2008)
Exercise training-induced lowering of inflammatory (CD14+CD16+) monocytes: a role in the anti-inflammatory influence of exercise?
Kyle L. Timmerman et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2008)
Dead adipocytes, detected as crown-like structures, are prevalent in visceral fat depots of genetically obese mice
I. Murano et al.
JOURNAL OF LIPID RESEARCH (2008)
Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding
Vered Elgazar-Carmon et al.
JOURNAL OF LIPID RESEARCH (2008)
Dynamics of fat cell turnover in humans
Kirsty L. Spalding et al.
NATURE (2008)
A Stress Signaling Pathway in Adipose Tissue Regulates Hepatic Insulin Resistance
Guadalupe Sabio et al.
SCIENCE (2008)
White fat progenitor cells reside in the adipose vasculature
Wei Tang et al.
SCIENCE (2008)
The role of interleukin-6 in insulin resistance, body fat distribution and energy balance
M. Hoene et al.
OBESITY REVIEWS (2008)
Adipocyte death, adipose tissue remodeling, and obesity complications
Katherine J. Strissel et al.
DIABETES (2007)
Adipocyte-derived serum amyloid A3 and hyaluronan play a role monocyte recruitment and adhesion
Chang Yeop Han et al.
DIABETES (2007)
Adipogenesis in obesity requires close interplay between differentiating adipocytes, strontal cells, and blood vessels
Satoshi Nishimura et al.
DIABETES (2007)
Macrophage infiltration into omental versus subcutaneous fat across different populations:: Effect of regional adiposity and the comorbidities of obesity
Ilana Harman-Boehm et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)
Interleukin-1-receptor antagonist in type 2 diabetes mellitus
Claus M. Larsen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2007)
Angiogenic role of LYVE-1-positive macrophages in adipose tissue
Chung-Hyun Cho et al.
CIRCULATION RESEARCH (2007)
Diet-induced increases in adiposity, but not plasma lipids, promote macrophage infiltration into white adipose tissue
Kimberly R. Coenen et al.
DIABETES (2007)
Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteins
Carey N. Lumeng et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2007)
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
Carey N. Lumeng et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Interleukin-1 beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression
Jennifer Jager et al.
ENDOCRINOLOGY (2007)
Role of the Toll-like receptor 4/NF-kappa B pathway in saturated fatty acid-induced inflammatory changes in the interaction between adipocytes and macrophages
Takayoshi Suganami et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)
Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation
Naomi Hosogai et al.
DIABETES (2007)
Absence of CC chemokine ligand 2 does not limit obesity-associated infiltration of macrophages into adipose tissue
Karen E. Inouye et al.
DIABETES (2007)
Attenuation of leptin and insulin signaling by SOCS proteins
Jane K. Howard et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2006)
Long-term treatment with interleukin-1β induces insulin resistance in murine and human adipocytes
C. Lagathu et al.
DIABETOLOGIA (2006)
The association of total and differential white blood cell count with metabolic syndrome in type 2 diabetic patients
Wan Sub Shim et al.
DIABETES RESEARCH AND CLINICAL PRACTICE (2006)
Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance
Gurol Tuncman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Acute-phase serum amyloid A: An inflammatory adipokine and potential link between obesity and its metabolic complications
Rong-Ze Yang et al.
PLOS MEDICINE (2006)
Increased infiltration of macrophages in omental adipose tissue is associated with marked hepatic lesions in morbid human obesity
Raffaella Cancello et al.
DIABETES (2006)
Diet and exercise reduce low-grade inflammation and macrophage infiltration in adipose tissue but not in skeletal muscle in severely obese subjects
JM Bruun et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2006)
Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion
PG Fallon et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Mechanisms of disease - The many roles of chemokines and chemokine receptors in inflammation
IF Charo et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Globular adiponectin decreases leptin-induced tumor necrosis factor-α expression by murine macrophages:: Involvement of cAMP-PKA and MAPK pathways
T Zhao et al.
CELLULAR IMMUNOLOGY (2005)
Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
S Cinti et al.
JOURNAL OF LIPID RESEARCH (2005)
Influence of exercise training and age on CD14+cell-surface expression of toll-like receptor 2 and 4
LK Stewart et al.
BRAIN BEHAVIOR AND IMMUNITY (2005)
The physiological regulation of toll-like receptor expression and function in humans
GI Lancaster et al.
JOURNAL OF PHYSIOLOGY-LONDON (2005)
Hypoxia-induced neutrophil survival is mediated by HIF-1α-dependent NF-κB activity
SR Walmsley et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
The weight of leptin in immunity
A La Cava et al.
NATURE REVIEWS IMMUNOLOGY (2004)
Differential effects of interleukin-6 and-10 on skeletal muscle and liver insulin action in vivo
HJ Kim et al.
DIABETES (2004)
Possible novel therapy for diabetes with cell-permeable JNK-inhibitory peptide
H Kaneto et al.
NATURE MEDICINE (2004)
The effects of dietary lipids on dendritic cells in perinodal adipose tissue during chronic mild inflammation
CA Mattacks et al.
BRITISH JOURNAL OF NUTRITION (2004)
Adipose tissue as an endocrine organ
EE Kershaw et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
U Özcan et al.
SCIENCE (2004)
Toll-like receptor 4 and CD14 mRNA expression are lower in resistive exercise-trained elderly women
MG Flynn et al.
JOURNAL OF APPLIED PHYSIOLOGY (2003)
IL-6 enhances plasma IL-1ra, IL-10, and cortisol in humans
A Steensberg et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2003)
HIF-1α is essential for myeloid cell-mediated inflammation
T Cramer et al.
CELL (2003)
Exercise and IL-6 infusion inhibit endotoxin-induced TNF-α production in humans
R Starkie et al.
FASEB JOURNAL (2003)
Serine phosphorylation of insulin receptor substrate 1 by inhibitor κB kinase complex
ZG Gao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
A central role for JNK in obesity and insulin resistance
J Hirosumi et al.
NATURE (2002)
SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2
LY Rui et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
New IL-17 family members promote Th1 or Th2 responses in the lung: In vivo function of the novel cytokine IL-25
SD Hurst et al.
JOURNAL OF IMMUNOLOGY (2002)
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
WC Knowler et al.
NEW ENGLAND JOURNAL OF MEDICINE (2002)
Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action
V Aguirre et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
IL-25 induces IL-4 IL-5, and IL-13 and Th2-associated pathologies in vivo
MM Fort et al.
IMMUNITY (2001)
Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4
JY Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
HIFα targeted for VHL-mediated destruction by proline hydroxylation:: Implications for O2 sensing
M Ivan et al.
SCIENCE (2001)
Targeting of HIF-α to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
P Jaakkola et al.
SCIENCE (2001)
C-reactive protein, inflammation, and innate immunity
RF Mortensen
IMMUNOLOGIC RESEARCH (2001)