Related references
Note: Only part of the references are listed.RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia
Filip Matthijssens et al.
JOURNAL OF CLINICAL INVESTIGATION (2021)
Ghrelin induces autophagy and CXCR4 expression via the SIRT1/AMPK axis in lymphoblastic leukemia cell lines
Masoud Heshmati et al.
CELLULAR SIGNALLING (2020)
Recent Advances in the Management of Acute Lymphoblastic Leukaemia
Katharine A. Hodby et al.
CURRENT TREATMENT OPTIONS IN ONCOLOGY (2020)
Treatment Outcome in Pediatric Acute Lymphoblastic Leukemia With Hyperleukocytosis in the Yeungnam Region of Korea: A Multicenter Retrospective Study
Kyung Mi Park et al.
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY (2020)
Acute lymphoblastic leukaemia
Florent Malard et al.
LANCET (2020)
Integrin-Mediated Adhesion and Chemoresistance of Acute Lymphoblastic Leukemia Cells Residing in the Bone Marrow or the Central Nervous System
Bibi Fatima Syed Shah Scharff et al.
FRONTIERS IN ONCOLOGY (2020)
Rho GDP-Dissociation Inhibitor 2 Inhibits C-X-C Chemokine Receptor Type 4-Mediated Acute Lymphoblastic Leukemia Cell Migration
Jixian Luo et al.
FRONTIERS IN ONCOLOGY (2020)
Reduced Morbidity and Mortality in Survivors of Childhood Acute Lymphoblastic Leukemia: A Report From the Childhood Cancer Survivor Study
Stephanie B. Dixon et al.
JOURNAL OF CLINICAL ONCOLOGY (2020)
The CXCR4 Antagonist, AMD3100, Reverses Mesenchymal Stem Cell-Mediated Drug Resistance in Relapsed/Refractory Acute Lymphoblastic Leukemia
Shan Wang et al.
ONCOTARGETS AND THERAPY (2020)
B-ALL Complexity: Is Targeted Therapy Still A Valuable Approach for Pediatric Patients?
Stefano Ratti et al.
CANCERS (2020)
Clinical trial update on bispecific antibodies, antibody-drug conjugates, and antibody-containing regimens for acute lymphoblastic leukemia
Delong Liu et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)
Bone Marrow Mesenchymal Stromal Cell-Derived Periostin Promotes B-ALL Progression by Modulating CCL2 in Leukemia Cells
Zhenling Ma et al.
CELL REPORTS (2019)
Mechanisms of extramedullary relapse in acute lymphoblastic leukemia: Reconciling biological concepts and clinical issues
Jeremie Gaudichon et al.
BLOOD REVIEWS (2019)
miR-101 Represses T-Cell Acute Lymphoblastic Leukemia by Targeting CXCR7/STAT3 Axis
Xue-Yi Yang et al.
ONCOLOGY RESEARCH (2019)
CXCR4 Inhibition with BL-8040 in Combination with Nelarabine in Patients with Relapsed or Refractory T-Cell Acute Lymphoblastic Leukemia / Lymphoblastic Lymphoma
Geoffrey L. Uy et al.
BLOOD (2019)
Recent advances on blinatumomab for acute lymphoblastic leukemia
Juanjuan Zhao et al.
EXPERIMENTAL HEMATOLOGY & ONCOLOGY (2019)
Molecular Players in Hematologic Tumor Cell Trafficking
Javier Redondo-Munoz et al.
FRONTIERS IN IMMUNOLOGY (2019)
T cell acute lymphoblastic leukemia (T-ALL): New insights into the cellular origins and infiltration mechanisms common and unique among hematologic malignancies
Eduardo Vadillo et al.
BLOOD REVIEWS (2018)
Role of CXCL12 and CXCR4 in the pathogenesis of hematological malignancies
Amnon Peled et al.
CYTOKINE (2018)
A guide to chemokines and their receptors
Catherine E. Hughes et al.
FEBS JOURNAL (2018)
Targeting the bone marrow microenvironment in acute leukemia
Christina Karantanou et al.
LEUKEMIA & LYMPHOMA (2018)
Dual Targeting of Acute Leukemia and Supporting Niche by CXCR4-Directed Theranostics
Stefan Habringer et al.
THERANOSTICS (2018)
92R Monoclonal Antibody Inhibits Human CCR9+ Leukemia Cells Growth in NSG Mice Xenografts
Beatriz Somovilla-Crespo et al.
FRONTIERS IN IMMUNOLOGY (2018)
Chemosensitivity is differentially regulated by the SDF-1/CXCR4 and SDF-1/CXCR7 axes in acute lymphoblastic leukemia with MLL gene rearrangements
Norie Ando et al.
LEUKEMIA RESEARCH (2018)
The role of ZAP70 kinase in acute lymphoblastic leukemia infiltration into the central nervous system
Ameera Alsadeq et al.
HAEMATOLOGICA (2017)
The role of ZAP70 kinase in acute lymphoblastic leukemia infiltration into the central nervous system
Ameera Alsadeq et al.
HAEMATOLOGICA (2017)
RhoA and RhoC are involved in stromal cell-derived factor-1-induced cell migration by regulating F-actin redistribution and assembly
Jixian Luo et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2017)
Opportunities for therapeutic antibodies directed at G-protein-coupled receptors (vol 16, pg 1, 2017)
Catherine J. Hutchings et al.
NATURE REVIEWS DRUG DISCOVERY (2017)
A phase 1 study of the CXCR4 antagonist plerixafor in combination with high-dose cytarabine and etoposide in children with relapsed or refractory acute leukemias or myelodysplastic syndrome: A Pediatric Oncology Experimental Therapeutics Investigators' Consortium study (POE 10-03)
Todd M. Cooper et al.
PEDIATRIC BLOOD & CANCER (2017)
Acute lymphoblastic leukemia: a comprehensive review and 2017 update
T. Terwilliger et al.
BLOOD CANCER JOURNAL (2017)
Wnt5a and CCL25 promote adult T-cell acute lymphoblastic leukemia cell migration, invasion and metastasis
Xinzhou Deng et al.
ONCOTARGET (2017)
The Role of the Central nervous System Microenvironment in Pediatric Acute Lymphoblastic Leukemia
Nathan P. Gossai et al.
FRONTIERS IN PEDIATRICS (2017)
The prognostic significance of serum XCL1 concentration in patients with acute lymphoblastic leukemia: a pilot study
Cesar Homero Gutierrez-Aguirre et al.
ANNALS OF HEMATOLOGY (2017)
Chemokines in the cancer microenvironment and their relevance in cancer immunotherapy
Nisha Nagarsheth et al.
NATURE REVIEWS IMMUNOLOGY (2017)
Protein epitope mimetic macrocycles as biopharmaceuticals
Anatol Luther et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2017)
Ex vivo drug response profiling detects recurrent sensitivity patterns in drug-resistant acute lymphoblastic leukemia
Viktoras Frismantas et al.
BLOOD (2017)
Advances in understanding the acute lymphoblastic leukemia bone marrow microenvironment: From biology to therapeutic targeting
Francesca Chiarini et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2016)
Effects of pharmacological and genetic disruption of CXCR4 chemokine receptor function in B-cell acute lymphoblastic leukaemia
Shubhchintan Randhawa et al.
BRITISH JOURNAL OF HAEMATOLOGY (2016)
CCR9 in cancer: oncogenic role and therapeutic targeting
Zhenbo Tu et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2016)
Role of CXCR4-mediated bone marrow colonization in CNS infiltration by T cell acute lymphoblastic leukemia
Tanja Rezzonico Jost et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2016)
CD9, a key actor in the dissemination of lymphoblastic leukemia, modulating CXCR4-mediated migration via RAC1 signaling
Marie-Pierre Arnaud et al.
BLOOD (2015)
Monoclonal antibodies in acute lymphoblastic leukemia
Elias Jabbour et al.
BLOOD (2015)
Chemokines and relapses in childhood acute lymphoblastic leukemia: A role in migration and in resistance to antileukemic drugs
Ana M. Gomez et al.
BLOOD CELLS MOLECULES AND DISEASES (2015)
CXCR4 Is Required for Leukemia-Initiating Cell Activity in T Cell Acute Lymphoblastic Leukemia
Diana Passaro et al.
CANCER CELL (2015)
CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance
Lauren A. Pitt et al.
CANCER CELL (2015)
Regulatory effect of chemokines in bone marrow niche
Ahmad Ahmadzadeh et al.
CELL AND TISSUE RESEARCH (2015)
CXCL12/CXCR4 axis in the pathogenesis of acute lymphoblastic leukemia (ALL): a possible therapeutic target
Aparecida de Lourdes Perim et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2015)
Molecular Pathways: Targeting the CXCR4-CXCL12 Axis-Untapped Potential in the Tumor Microenvironment
Stefania Scala
CLINICAL CANCER RESEARCH (2015)
Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration
Ching-Hon Pui et al.
JOURNAL OF CLINICAL ONCOLOGY (2015)
Genome-wide analyses identify KLF4 as an important negative regulator in T-cell acute lymphoblastic leukemia through directly inhibiting T-cell associated genes
Wei Li et al.
MOLECULAR CANCER (2015)
CXCR4 Protein Epitope Mimetic Antagonist POL5551 Disrupts Metastasis and Enhances Chemotherapy Effect in Triple-Negative Breast Cancer
Jingyu Xiang et al.
MOLECULAR CANCER THERAPEUTICS (2015)
Diphtheria-toxin based anti-human CCR4 immunotoxin for targeting human CCR4+ cells in vivo
Zhaohui Wang et al.
MOLECULAR ONCOLOGY (2015)
Acute Lymphoblastic Leukemia in Children
Stephen P. Hunger et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Concise Review: CXCR4/CXCL12 Signaling in Immature Hematopoiesis-Lessons From Pharmacological and Genetic Models
Darja Karpova et al.
STEM CELLS (2015)
POL5551, a novel and potent CXCR4 antagonist, enhances sensitivity to chemotherapy in pediatric ALL
Edward Allan R. Sison et al.
ONCOTARGET (2015)
Building better monoclonal antibody-based therapeutics
George J. Weiner
NATURE REVIEWS CANCER (2015)
Interleukin-15 enhances cellular proliferation and upregulates CNS homing molecules in pre-B acute lymphoblastic leukemia
Mark T. S. Williams et al.
BLOOD (2014)
Notch1-induced T cell leukemia can be potentiated by microenvironmental cues in the spleen
Shihui Ma et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2014)
High CXCR4 and low VLA-4 expression predicts poor survival in adults with acute lymphoblastic leukemia
Sun-Young Ko et al.
LEUKEMIA RESEARCH (2014)
Antitumor effects of a monoclonal antibody to human CCR9 in leukemia cell xenografts
Sonia Chamorro et al.
MABS (2014)
PTEN action in leukaemia dictated by the tissue microenvironment
Cornelius Miething et al.
NATURE (2014)
CXCR7 Is Highly Expressed in Acute Lymphoblastic Leukemia and Potentiates CXCR4 Response to CXCL12
Rita de Cassia Carvalho Melo et al.
PLOS ONE (2014)
Detection of occult cerebrospinal fluid involvement during maintenance therapy identifies a group of children with acute lymphoblastic leukemia at high risk for relapse
Carolina Martinez-Laperche et al.
AMERICAN JOURNAL OF HEMATOLOGY (2013)
Plerixafor (AMD3100) induces prolonged mobilization of acute lymphoblastic leukemia cells and increases the proportion of cycling cells in the blood in mice
Robert Welschinger et al.
EXPERIMENTAL HEMATOLOGY (2013)
Acute lymphoblastic leukaemia
Hiroto Inaba et al.
LANCET (2013)
Activated ERM Protein Plays a Critical Role in Drug Resistance of MOLT4 Cells Induced by CCL25
Li Zhang et al.
PLOS ONE (2013)
Structure of the CCR5 Chemokine Receptor-HIV Entry Inhibitor Maraviroc Complex
Qiuxiang Tan et al.
SCIENCE (2013)
Protumoral role of monocytes in human B-cell precursor acute lymphoblastic leukemia: involvement of the chemokine CXCL10
Yunqin Lee et al.
BLOOD (2012)
Notch1 regulates chemotaxis and proliferation by controlling the CC-chemokine receptors 5 and 9 in T cell acute lymphoblastic leukaemia
Leonardo Mirandola et al.
JOURNAL OF PATHOLOGY (2012)
Treatment of acute lymphoblastic leukemia with an rGel/BLyS fusion toxin
R. Parameswaran et al.
LEUKEMIA (2012)
CXCR4 inhibitors selectively eliminate CXCR4-expressing human acute myeloid leukemia cells in NOG mouse model
Y. Zhang et al.
CELL DEATH & DISEASE (2012)
Hematopoietic Stem Cell Development, Niches, and Signaling Pathways
Kamonnaree Chotinantakul et al.
BONE MARROW RESEARCH (2012)
Chemotherapy resistance in acute lymphoblastic leukemia requires hERG1 channels and is overcome by hERG1 blockers
Serena Pillozzi et al.
BLOOD (2011)
Phosphorylated CXCR4 Is Associated With Poor Survival in Adults With B-Acute Lymphoblastic Leukemia
Sergej Konoplev et al.
CANCER (2011)
CXCR3 ligands: redundant, collaborative and antagonistic functions
Joanna R. Groom et al.
IMMUNOLOGY AND CELL BIOLOGY (2011)
Leukemia Stem Cells and Microenvironment: Biology and Therapeutic Targeting
Marina Y. Konopleva et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Osteoclasts are dispensable for hematopoietic stem cell maintenance and mobilization
Kana Miyamoto et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Combination of drug therapy in acute lymphoblastic leukemia with a CXCR4 antagonist
R. Parameswaran et al.
LEUKEMIA (2011)
Rac-1 GTPase controls the capacity of human leukaemic lymphoblasts to migrate on fibronectin in response to SDF-1α (CXCL12)
Manuel Freret et al.
LEUKEMIA RESEARCH (2011)
Role of Rho-ROCK signaling in MOLT4 cells metastasis induced by CCL25
Li Zhang et al.
LEUKEMIA RESEARCH (2011)
Specific killing of CCR9 high-expressing acute T lymphocytic leukemia cells by CCL25 fused with PE38 toxin
Yi Hu et al.
LEUKEMIA RESEARCH (2011)
Identification of Hepatic Niche Harboring Human Acute Lymphoblastic Leukemic Cells via the SDF-1/CXCR4 Axis
Itaru Kato et al.
PLOS ONE (2011)
Increased CCL2 and IL-8 in the Bone Marrow Microenvironment in Acute Lymphoblastic Leukemia
Jaira Ferreira de Vasconcellos et al.
PEDIATRIC BLOOD & CANCER (2011)
Attenuation of CXCR4 Responses by CCL18 in Acute Lymphocytic Leukemia B Cells
J. Catusse et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2010)
Ezrin is a key molecule in the metastasis of MOLT4 cells induced by CCL25/CCR9
Beibei Zhou et al.
LEUKEMIA RESEARCH (2010)
Therapeutic targeting of chemokine interactions in atherosclerosis
Rory R. Koenen et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Pharmacology of AMD3465: A small molecule antagonist of the chemokine receptor CXCR4
Veronique Bodart et al.
BIOCHEMICAL PHARMACOLOGY (2009)
Inhibition of the SDF-1α-CXCR4 axis by the CXCR4 antagonist AMD3100 suppresses the migration of cultured cells from ATL patients and murine lymphoblastoid cells from HTLV-I Tax transgenic mice
Akira Kawaguchi et al.
BLOOD (2009)
CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling
Angelique Levoye et al.
BLOOD (2009)
CXCR4 mediates the homing of B cell progenitor acute lymphoblastic leukaemia cells to the bone marrow via activation of p38MAPK
Julius G. Juarez et al.
BRITISH JOURNAL OF HAEMATOLOGY (2009)
The Mechanism of Chemokine Receptor 9 Internalization Triggered by Interleukin 2 and Interleukin 4
Xiaoling Tong et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2009)
Proof of Activity with AMD11070, an Orally Bioavailable Inhibitor of CXCR4-Tropic HIV Type 1
Graeme Moyle et al.
CLINICAL INFECTIOUS DISEASES (2009)
Therapeutic targeting of microenvironmental interactions in leukemia: Mechanisms and approaches
Marina Konopleva et al.
DRUG RESISTANCE UPDATES (2009)
CXCR4 antagonists: targeting the microenvironment in leukemia and other cancers
J. A. Burger et al.
LEUKEMIA (2009)
Contribution of bone microenvironment to leukemogenesis and leukemia progression
F. Ayala et al.
LEUKEMIA (2009)
CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia
Silvia Buonamici et al.
NATURE (2009)
Stem cells and niches: Mechanisms that promote stem cell maintenance throughout life
Sean J. Morrison et al.
CELL (2008)
Current management and challenges of malignant disease in the CNS in paediatric leukaemia
Ching-Hon Pui et al.
LANCET ONCOLOGY (2008)
Comparison of the Potential Multiple Binding Modes of Bicyclam, Monocylam, and Noncyclam Small-Molecule CXC Chemokine Receptor 4 Inhibitors
Rebecca S. Y. Wong et al.
MOLECULAR PHARMACOLOGY (2008)
A new class of anti-HIV therapy and new challenges
Raphael Dolin
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Chemokine CXCL12 enhances proliferation in pre-B-ALL via STAT5 activation
Frida Mowafi et al.
PEDIATRIC BLOOD & CANCER (2008)
Multiple-dose escalation study of the safety, pharmacokinetics, and biologic activity of oral AMD070, a selective CXCR4 receptor inhibitor, in human subjects
Nimalie D. Stone et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2007)
CXCR4 antagonists mobilize childhood acute lymphoblastic leukemia cells into the peripheral blood and inhibit engraftment
J. Juarez et al.
LEUKEMIA (2007)
Interaction of interleukin-7 and interleukin-3 with the CXCL12-induced proliferation of B-cell progenitor acute lymphoblastic leukemia
Julius Juarez et al.
HAEMATOLOGICA (2007)
The pleiotropic effects of the SDF-1-CXCR4 axis in organogenesis, regeneration and tumorigenesis
M. Z. Ratajczak et al.
LEUKEMIA (2006)
MCP-1 in the cerebrospinal fluid of children with acuite lymphoblastic leukemia
Arik Eisenkraft et al.
LEUKEMIA RESEARCH (2006)
Chemokine receptor expression and function in childhood acute lymphoblastic leukemia of B-lineage
A Corcione et al.
LEUKEMIA RESEARCH (2006)
Defective p38 mitogen-activated protein kinase signaling impairs chemotaxic but not proliferative responses to stromal-derived factor-1α in acute lymphoblastic leukemia
LJ Bendall et al.
CANCER RESEARCH (2005)
Unique SDF-1-induced activation of human precursor-B ALL cells as a result of altered CXCR4 expression and signaling
A Spiegel et al.
BLOOD (2004)
Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche
F Arai et al.
CELL (2004)
Identification of a CXCR4 antagonist, a T140 analog, as an anti-rheumatoid arthritis agent
H Tamamura et al.
FEBS LETTERS (2004)
CC chemokine ligand 25 enhances resistance to apoptosis in CD4+ T cells from patients with T-cell lineage acute and chronic lymphocytic leukemia by means of livin activation
QP Zhang et al.
CANCER RESEARCH (2004)
Effects of inhibitors of the chemokine receptor CXCR4 on acute lymphoblastic leukemia cells in vitro
J Juarez et al.
LEUKEMIA (2003)
PARC/CCL18 is a plasma CC chemokine with increased levels in childhood acute lymphoblastic leukemia
S Struyf et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
Chemokine receptor inhibition by AMD3100 is strictly confined to CXCR4
S Hatse et al.
FEBS LETTERS (2002)
High expression of the chemokine receptor CXCR4 predicts extramedullary organ infiltration in childhood acute lymphoblastic leukaemia
R Crazzolara et al.
BRITISH JOURNAL OF HAEMATOLOGY (2001)
Differential expression of chemokine receptors in B cell malignancies
J Dürig et al.
LEUKEMIA (2001)
Pharmacokinetics and safety of AMD-3100, a novel antagonist of the CXCR-4 chemokine receptor, in human volunteers
CW Hendrix et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2000)