Journal
JOURNAL OF GENETICS AND GENOMICS
Volume 48, Issue 2, Pages 107-114Publisher
SCIENCE PRESS
DOI: 10.1016/j.jgg.2021.02.006
Keywords
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Funding
- National Key Research and Development Project [2020YFC0842300]
- Strategic Priority Research Program of the Chinese Academy of Sciences [XDB29040201]
- National Natural Science Foundation of China [81901680]
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The ongoing COVID-19 pandemic has accelerated the development of mRNA vaccines, with positive results reported and future challenges ahead.
The ongoing COVID-19 pandemic and its unprecedented global societal and economic disruptive impact highlight the urgent need for safe and effective vaccines. Taking substantial advantages of versatility and rapid development, two mRNA vaccines against COVID-19 have completed late-stage clinical assessment at an unprecedented speed and reported positive results. In this review, we outline keynotes in mRNA vaccine development, discuss recently published data on COVID-19 mRNA vaccine candidates, focusing on those in clinical trials and analyze future potential challenges. Copyright (C) 2021, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, and Genetics Society of China. Published by Elsevier Limited and Science Press. All rights reserved.
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