Related references
Note: Only part of the references are listed.Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer
Yang Chen et al.
CANCER CELL (2021)
Role of hypoxia inducible factor-1 in cancer stem cells
Qi Zhang et al.
MOLECULAR MEDICINE REPORTS (2021)
Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer
Eric C. Cheung et al.
CANCER CELL (2020)
ROS in cancer therapy: the bright side of the moon
Bruno Perillo et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2020)
NADPH oxidase 1 mediates caerulein-induced pancreatic fibrosis in chronic pancreatitis
Di Xia et al.
FREE RADICAL BIOLOGY AND MEDICINE (2020)
TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1
Jie Su et al.
NATURE (2020)
Cysteine depletion induces pancreatic tumor ferroptosis in mice
Michael A. Badgley et al.
SCIENCE (2020)
Transforming Growth Factor-β Signaling in Immunity and Cancer
Eduard Batlle et al.
IMMUNITY (2019)
ROS/KRAS/AMPK Signaling Contributes to Gemcitabine-Induced Stem-like Cell Properties in Pancreatic Cancer
Hengqiang Zhao et al.
MOLECULAR THERAPY-ONCOLYTICS (2019)
A hierarchical network of hypoxia-inducible factor and SMAD proteins governs procollagen lysyl hydroxylase 2 induction by hypoxia and transforming growth factor?1
Tamara Rosell-Garcia et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Autocrine TGFβ Is a Survival Factor for Monocytes and Drives Immunosuppressive Lineage Commitment
Alba Gonzalez-Junca et al.
CANCER IMMUNOLOGY RESEARCH (2019)
ROS and the DNA damage response in cancer
Upadhyayula Sai Srinivas et al.
REDOX BIOLOGY (2019)
Redox Imbalance in Intestinal Fibrosis: Beware of the TGF beta-1, ROS, and Nrf2 Connection
Giovanni Latella
DIGESTIVE DISEASES AND SCIENCES (2018)
Targeting reactive oxygen species in development and progression of pancreatic cancer
Nisha Durand et al.
EXPERT REVIEW OF ANTICANCER THERAPY (2017)
Cancer-FOXP3 directly activated CCL5 to recruit FOXP3+ Treg cells in pancreatic ductal adenocarcinoma
X. Wang et al.
ONCOGENE (2017)
TGFβ engages MEK/ERK to differentially regulate benign and malignant pancreas cell function
D. R. Principe et al.
ONCOGENE (2017)
Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression
Hanane Laklai et al.
NATURE MEDICINE (2016)
Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions
Geou-Yarh Liou et al.
CELL REPORTS (2016)
Loss of SOD3 (EcSOD) Expression Promotes an Aggressive Phenotype in Human pancreatic Ductal Adenocarcinoma
Brianne R. O'Leary et al.
CLINICAL CANCER RESEARCH (2015)
Increased Oxidative Stress as a Selective Anticancer Therapy
Jiahui Liu et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2015)
Transforming Growth Factor-Beta and Oxidative Stress Interplay: Implications in Tumorigenesis and Cancer Progression
Jelena Krstic et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2015)
Myeloid-derived suppressor cells in major depression patients suppress T-cell responses through the production of reactive oxygen species
Jianyang Wei et al.
PSYCHIATRY RESEARCH (2015)
TGF-β-induced hCG-β regulates redox homeostasis in glioma cells
Fahim Ahmad et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2015)
JNK suppression of chemotherapeutic agents-induced ROS confers chemoresistance on pancreatic cancer stem cells
Shuhei Suzuki et al.
ONCOTARGET (2015)
A mitochondrial thioredoxin-sensitive mechanism regulates TGF-β-mediated gene expression associated with epithelial-mesenchymal transition
Fumihiro Ishikawa et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival
Berna C. Oezdemir et al.
CANCER CELL (2014)
Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma
Andrew D. Rhim et al.
CANCER CELL (2014)
Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation
M. Ogrunc et al.
CELL DEATH AND DIFFERENTIATION (2014)
Oxidative stress mediates the conversion of endothelial cells into myofibroblasts via a TGF-β1 and TGF-β2-dependent pathway
Ignacio Montorfano et al.
LABORATORY INVESTIGATION (2014)
Reactive Oxygen Species Prevent Imiquimod-Induced Psoriatic Dermatitis through Enhancing Regulatory T Cell Function
Hyung-Ran Kim et al.
PLOS ONE (2014)
The cancer stem cell niche: cross talk between cancer stem cells and their microenvironment
Jun Ye et al.
TUMOR BIOLOGY (2014)
Can nanomedicines kill cancer stem cells?
Yi Zhao et al.
ADVANCED DRUG DELIVERY REVIEWS (2013)
Oxidative stress and cancer: An overview
Venus Sosa et al.
AGEING RESEARCH REVIEWS (2013)
Oxidative Stress Induced by Inactivation of TP53INP1 Cooperates with KrasG12D to Initiate and Promote Pancreatic Carcinogenesis in the Murine Pancreas
Talal Al Saati et al.
AMERICAN JOURNAL OF PATHOLOGY (2013)
Mitochondrial Reactive Oxygen Species Regulate Transforming Growth Factor-β Signaling
Manu Jain et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Modulation of oxidative stress as an anticancer strategy
Chiara Gorrini et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
Endothelial Cell HIF-1α and HIF-2α Differentially Regulate Metastatic Success
Cristina Branco-Price et al.
CANCER CELL (2012)
K-rasG12V transformation leads to mitochondrial dysfunction and a metabolic switch from oxidative phosphorylation to glycolysis
Yumin Hu et al.
CELL RESEARCH (2012)
Metabolic Plasticity in Stem Cell Homeostasis and Differentiation
Clifford D. L. Folmes et al.
CELL STEM CELL (2012)
Reactive oxygen species stimulates epithelial mesenchymal transition in normal human epidermal keratinocytes via TGF-beta secretion
Teruhisa Fukawa et al.
EXPERIMENTAL CELL RESEARCH (2012)
Nox4 involvement in TGF-beta and SMAD3-driven induction of the epithelial-to-mesenchymal transition and migration of breast epithelial cells
Howard E. Boudreau et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice
Meredith A. Collins et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Myeloid-derived suppressor cells from tumor-bearing mice impair TGF-β-induced differentiation of CD4+CD25+FoxP3+ Tregs from CD4+CD25-FoxP3- T cells
Sara M. Centuori et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2012)
Autophagy in Idiopathic Pulmonary Fibrosis
Avignat S. Patel et al.
PLOS ONE (2012)
A Central Role for RAF→MEK→ERK Signaling in the Genesis of Pancreatic Ductal Adenocarcinoma
Eric A. Collisson et al.
CANCER DISCOVERY (2012)
TGF-β1 increases invasiveness of SW1990 cells through Rac1/ROS/NF-κB/IL-6/MMP-2
Marcelo G. Binker et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Hypoxia-mediated drug resistance: Novel insights on the functional interaction of HIFs and cell death pathways
Nadine Rohwer et al.
DRUG RESISTANCE UPDATES (2011)
Mitochondrial and energy metabolism-related properties as novel indicators of lung cancer stem cells
Xiao-Qun Ye et al.
INTERNATIONAL JOURNAL OF CANCER (2011)
Heterogeneity of Mitochondrial Membrane Potential: A Novel Tool to Isolate and Identify Cancer Stem Cells from a Tumor Mass?
Xiao-Qun Ye et al.
STEM CELL REVIEWS AND REPORTS (2011)
Hypoxia inducible factors in cancer stem cells
J. M. Heddleston et al.
BRITISH JOURNAL OF CANCER (2010)
Potential use of the anti-inflammatory drug, sulfasalazine, for targeted therapy of pancreatic cancer
P. W. Gout et al.
Current Oncology (2010)
Hepatitis C Virus Regulates Transforming Growth Factor β1 Production Through the Generation of Reactive Oxygen Species in a Nuclear Factor κB-Dependent Manner
Wenyu Lin et al.
GASTROENTEROLOGY (2010)
Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells
Zhizhong Li et al.
CANCER CELL (2009)
Tumor-derived TGF-beta Mediates Conversion of CD4(+)Foxp3(+) Regulatory T Cells in a Murine Model of Pancreas Cancer
Tricia A. Moo-Young et al.
JOURNAL OF IMMUNOTHERAPY (2009)
Association of reactive oxygen species levels and radioresistance in cancer stem cells
Maximilian Diehn et al.
NATURE (2009)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
SCIENCE (2009)
NADPH oxidase plays a crucial role in the activation of pancreatic stellate cells
Atsushi Masamune et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2008)
The Activated Stroma Index Is a Novel and Independent Prognostic Marker in Pancreatic Ductal Adenocarcinoma
Mert Erkan et al.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2008)
A Cre-IoXP-based mouse model for conditional somatic gene expression and knockdown in vivo by using avian retroviral vectors
Barbara Seidler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
Sian Jones et al.
SCIENCE (2008)
Dynamics of the immune reaction to pancreatic cancer from inception to invasion
Carolyn E. Clark et al.
CANCER RESEARCH (2007)
TGF-β activates Erk MAP kinase signalling through direct phosphorylation of ShcA
Matt K. Lee et al.
EMBO JOURNAL (2007)
Detection and characterization of tumor hypoxia using pO2 histography
Peter Vaupel et al.
ANTIOXIDANTS & REDOX SIGNALING (2007)
Isoform-specific activation of latent transforming growth factor β (LTGF-β) by reactive oxygen species
Michael E. Jobling et al.
RADIATION RESEARCH (2006)
Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma:: HIF-2α promotes an aggressive phenotype
Linda Holmquist-Mengelbier et al.
CANCER CELL (2006)
The use of targeted mouse models for preclinical testing of novel cancer therapeutics
Kenneth P. Olive et al.
CLINICAL CANCER RESEARCH (2006)
Increased prevalence of regulatory T cells (Treg) is induced by pancreas adenocarcinorna
Udaya K. Liyanage et al.
JOURNAL OF IMMUNOTHERAPY (2006)
Hypoxia signalling in cancer and approaches to enforce tumour regression
Jacques Pouyssegur et al.
NATURE (2006)
Amelioration of pancreatic fibrosis in mice with defective TGF-β signaling
BM Yoo et al.
PANCREAS (2005)
TGF β1 induces prolonged mitochondrial ROS generation through decreased complex IV activity with senescent arrest in Mv1Lu cells
YS Yoon et al.
ONCOGENE (2005)
TGF-β induces Foxp3+T-regulatory cells from CD4+CD25-precursors
S Fu et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2004)
Transforming growth factor β1 induction of tissue inhibitor of metalloproteinases 3 in articular chondrocytes is mediated by reactive oxygen species
WQ Li et al.
FREE RADICAL BIOLOGY AND MEDICINE (2004)
Inhibition of transforming growth factor β decreases pancreatic fibrosis and protects the pancreas against chronic injury in mice
Y Nagashio et al.
LABORATORY INVESTIGATION (2004)
Rat pancreatic stellate cells secrete matrix metal loproteinases: implications for extracellular matrix turnover
PA Phillips et al.
GUT (2003)
Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1(-/-) mice
M Scortegagna et al.
NATURE GENETICS (2003)
Expression of transforming growth factor-β1 by pancreatic stellate cells and its implications for matrix secretion and turnover in chronic pancreatitis
FWT Shek et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Expression of TGF-βs and their receptors is differentially modulated by reactive oxygen species and nitric oxide in human articular chondrocytes
N Ayache et al.
OSTEOARTHRITIS AND CARTILAGE (2002)
TGF beta-induced fibrogenesis of the pancreas
A Menke et al.
JOURNAL OF GASTROINTESTINAL CANCER (2002)
Smad4 mediates activation of mitogen-activated protein kinases by TGF-β in pancreatic acinar cells
DM Simeone et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2001)
Effects of fibrogenic mediators on the development of pancreatic fibrosis in a TGF-beta 1 transgenic mouse model
R Vogelmann et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2001)
Pancreatic tumors show high levels of hypoxia
AC Koong et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2000)
Reactive oxygen species activate mitogen-activated protein kinases in pancreatic acinar cells
A Dabrowski et al.
PANCREAS (2000)
Share Paper
