4.1 Article

Duration of Treatment in Electroconvulsive Therapy Among Patients Beginning With Acute Course Right Unilateral Brief Pulse Stimuli

Journal

JOURNAL OF ECT
Volume 37, Issue 4, Pages 238-242

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/YCT.0000000000000768

Keywords

electroconvulsive therapy; cohort studies; survival analysis; brief pulse

Funding

  1. National Institute of Mental Health [R25MH094612, R56MH115187, R01MH120991, 5R01MH112737-03]
  2. National Institute on Aging [5R01AG061100-02]
  3. Brain and Behavior Research Foundation [NARSAD 26489]

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This study analyzed the time in first lifetime acute course RUL-BP ECT for 1383 patients, revealing that 37.5% of patients were transitioned from RUL to bilateral treatments, while over 60% of patients continued to exclusively use RUL-BP parameters throughout their acute course.
Objectives Right unilateral brief pulse (RUL-BP) electroconvulsive therapy (ECT) has been adopted as a technique for reducing the cognitive side effects of ECT relative to sine wave or bilateral treatments, but it is unknown how often patients are transitioned to alternative electrode placements. This study analyzes time in first lifetime acute course RUL-BP ECT. Methods A single-center retrospective chart review was conducted of adult patients receiving a first lifetime course of ECT from 2000 to 2017 beginning with individualized seizure threshold determination using RUL-BP treatment parameters. Results A total of 1383 patients met study criteria and received a mean number of 9.4 +/- 3.1 treatments, of which 7.6 +/- 3.3 were using RUL-BP stimuli. Only 37.5% of patients were transitioned from RUL to bilateral treatments. Younger patients and those diagnosed with bipolar disorder were more likely to transition from RUL-BP to bilateral treatments, but the overall number of treatments did not differ based on age or primary diagnosis. Conclusions Among patients who begin treatment with RUL-BP ECT, more than 60% use exclusively those parameters throughout their acute course.

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