Journal
JOURNAL OF CRANIOFACIAL SURGERY
Volume 32, Issue 7, Pages 2468-2470Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/SCS.0000000000007673
Keywords
Cleft lip; cleft palate; prenatal ultrasound
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The study suggests that complete CL and associated cleft palate are significantly associated with the accuracy of prenatal diagnosis. Parents are more satisfied with true-positive prenatal diagnosis and perceive knowing their child's diagnosis in advance to be more helpful. Therefore, these results can aid physicians in providing more informed prenatal counseling.
Factors impacting the accuracy of ultrasound (US) diagnosis of cleft lip (CL) and its subsequent effect on parents are not well understood. Our objectives were to evaluate how the type of CL (complete versus incomplete) and associated cleft palate affect the accuracy of CL's prenatal diagnosis and to evaluate differences between parents' perception of prenatal US in cases of true-positive versus false-negative results. The authors performed a retrospective review of all patients who underwent repair for nonsyndromic CL following prenatal US. Patients were stratified by type of CL and associated cleft palate. Parents were called to determine if their child's CL was diagnosed via US and their perception of the results. Forty-seven children with complete and 40 with incomplete CL responded to phone calls. The presence of a complete CL (P = 0.001) and an associated cleft palate (P = 0.014) were independently associated with an increased likelihood of prenatal diagnosis. Parents who received a true-positive prenatal diagnosis of CL were more satisfied than those who received a false-negative diagnosis (P = 0.0063). True-positives perceived knowing of their child's diagnosis in advance to be more helpful than false-negatives believed it would have been. These results afford an improved context to interpret US studies and help physicians provide more informed prenatal counseling.
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