Journal
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
Volume 41, Issue 7, Pages 1791-1793Publisher
SAGE PUBLICATIONS INC
DOI: 10.1177/0271678X211009362
Keywords
Caloric restriction; cerebral ischemia; preconditioning; inflammation; cell death
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A proper diet is crucial for health and longevity. Intermittent fasting shows benefits in mitigating metabolic disorders and reducing the risk of age-related diseases like heart attack, stroke and dementia through altered epigenetic and transcriptional programming.
A proper diet is important for health and longevity. Controlling the amount of food consumed is immensely beneficial as it promotes multiple cellular and molecular protective mechanisms and simultaneously prevents toxic mechanisms. Intermittent fasting (IF) is a flexible and easy-to-adopt dietary modification that helps to mitigate metabolic disorders like diabetes and hypertension, and thus the devastating age-related diseases like heart attack, stroke and dementia. The benefits of IF seem to be mediated by altered epigenetic and transcriptional programming leading to reduced oxidative stress, inflammation, mitochondrial damage and cell death.
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