Related references
Note: Only part of the references are listed.Inhibition of nucleophosmin 1 suppresses colorectal cancer tumor growth of patient -derived xenografts via activation of p53 and inhibition of AKT
Angel C. Y. Yu et al.
CANCER BIOLOGY & THERAPY (2021)
Biological and therapeutic implications of a unique subtype of NPM1 mutated AML
Arvind Singh Mer et al.
NATURE COMMUNICATIONS (2021)
Favorable outcomes for allogeneic hematopoietic cell transplantation in elderly patients with NPM1-mutated and FLT3-ITD-negative acute myeloid leukemia
Ibrahim Aldoss et al.
BONE MARROW TRANSPLANTATION (2020)
Analysis of the clinical impact of NPM1 mutant allele burden in a large cohort of younger adult patients with acute myeloid leukaemia
David C. Linch et al.
BRITISH JOURNAL OF HAEMATOLOGY (2020)
Nucleophosmin mutations confer an independent favorable prognostic impact in 869 pediatric patients with acute myeloid leukemia
Lu-Hong Xu et al.
BLOOD CANCER JOURNAL (2020)
NPM1 upregulates the transcription of PD-L1 and suppresses T cell activity in triple-negative breast cancer
Ge Qin et al.
NATURE COMMUNICATIONS (2020)
Nucleophosmin 1 Mutations in Acute Myeloid Leukemia
Jabra Zarka et al.
GENES (2020)
Nucleophosmin in Its Interaction with Ligands
Ilaria Cela et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Impact of gemtuzumab ozogamicin on MRD and relapse risk in patients with NPM1-mutated AML: results from the AMLSG 09-09 trial
Silke Kapp-Schwoerer et al.
BLOOD (2020)
The prognostic impact of FLT3-ITD and NPM1 mutation in adult AML is age-dependent in the population-based setting
Gunnar Juliusson et al.
BLOOD ADVANCES (2020)
Phosphoproteome Profiling Reveals Multifunctional Protein NPM1 as part of the Irradiation Response of Tumor Cells
Nadine Wiesmann et al.
TRANSLATIONAL ONCOLOGY (2019)
High NPM1 mutant allele burden at diagnosis correlates with minimal residual disease at first remission in de novo acute myeloid leukemia
Sanjay S. Patel et al.
AMERICAN JOURNAL OF HEMATOLOGY (2019)
Chromosomal Abnormalities and Prognosis in NPM1-Mutated Acute Myeloid Leukemia: A Pooled Analysis of Individual Patient Data From Nine International Cohorts
Linus Angenendt et al.
JOURNAL OF CLINICAL ONCOLOGY (2019)
New insights into the biology of acute myeloid leukemia with mutated NPM1
Lorenzo Brunetti et al.
INTERNATIONAL JOURNAL OF HEMATOLOGY (2019)
Knockdown of nucleophosmin 1 suppresses proliferation of triple-negative breast cancer cells through activating CDH1/Skp2/p27kip1 pathway
De Zeng et al.
CANCER MANAGEMENT AND RESEARCH (2019)
NPM1 mutant variant allele frequency correlates with leukemia burden but does not provide prognostic information in NPM1-mutated acute myeloid leukemia
Hussein A. Abbas et al.
AMERICAN JOURNAL OF HEMATOLOGY (2019)
High NPM1-mutant allele burden at diagnosis predicts unfavorable outcomes in de novo AML
Sanjay S. Patel et al.
BLOOD (2018)
When the good go bad: Mutant NPM1 in acute myeloid leukemia
Preethi Kunchala et al.
BLOOD REVIEWS (2018)
On the relationship status for Arf and NPM1-it's complicated
Diana M. Mitrea et al.
FEBS JOURNAL (2018)
Identification of a novel nucleophosmin-interaction motif in the tumor suppressor p14arf
Enrico Luchinat et al.
FEBS JOURNAL (2018)
A novel type of NPM1 mutation characterized by multiple internal tandem repeats in a case of cytogenetically normal acute myeloid leukemia
Nicolas Duployez et al.
HAEMATOLOGICA (2018)
Nucleolus as an emerging hub in maintenance of genome stability and cancer pathogenesis
Mikael S. Lindstrom et al.
ONCOGENE (2018)
Analysis of the oligomeric states of nucleophosmin using size exclusion chromatography
Gyosuke Sakashita et al.
SCIENTIFIC REPORTS (2018)
A novel type of NPM1 mutation characterized by multiple internal tandem repeats in a case of cytogenetically normal acute myeloid leukemia
Nicolas Duployez et al.
HAEMATOLOGICA (2018)
Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel
Hartmut Doehner et al.
BLOOD (2017)
Comparative value of post-remission treatment in cytogenetically normal AML subclassified by NPM1 and FLT3-ITD allelic ratio
J. Versluis et al.
LEUKEMIA (2017)
Biological and clinical consequences of NPM1 mutations in AML
E. M. Heath et al.
LEUKEMIA (2017)
Complex molecular genetic abnormalities involving three or more genetic mutations are important prognostic factors for acute myeloid leukemia
S. Wakita et al.
LEUKEMIA (2016)
Both high expression of nucleophosmin/B23 and CRM1 predicts poorer prognosis in human gastric cancer
Fang Zhou et al.
APMIS (2016)
Nucleophosmin: from structure and function to disease development
Joseph K. Box et al.
BMC MOLECULAR BIOLOGY (2016)
Proteomics Analysis of Up-regulated NPM1 Protein in Colorectal Cancer
Wang Hai et al.
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES (2016)
Assessment of Minimal Residual Disease in Standard-Risk AML
A. Ivey et al.
NEW ENGLAND JOURNAL OF MEDICINE (2016)
Implication of NPM1 phosphorylation and preclinical evaluation of the nucleoprotein antagonist N6L in prostate cancer
Damien Destouches et al.
ONCOTARGET (2016)
14-3-3γ Prevents Centrosome Amplification and Neoplastic Progression
Amitabha Mukhopadhyay et al.
SCIENTIFIC REPORTS (2016)
Acute Myeloid Leukemia: A Concise Review
Jennifer N. Saultz et al.
JOURNAL OF CLINICAL MEDICINE (2016)
Arsenic trioxide and all-trans retinoic acid target NPM1 mutant oncoprotein levels and induce apoptosis in NPM1-mutated AML cells
Maria Paola Martelli et al.
BLOOD (2015)
NPM1: A new downstream effector of PI3K-AKT-mTOR pathway in prostate cancer?
Rafik Boudra et al.
MOLECULAR CANCER THERAPEUTICS (2015)
Acute myeloid leukemia in patients older than 75: prognostic impact of FLT3-ITD and NPM1 mutations
Pierre Hirsch et al.
LEUKEMIA & LYMPHOMA (2015)
Impact of FLT3ITD mutant allele level on relapse risk in intermediate-risk acute myeloid leukemia
David C. Linch et al.
BLOOD (2014)
Deregulated expression of Nucleophosmin 1 in gastric cancer and its clinicopathological implications
Mariana Ferreira Leal et al.
BMC GASTROENTEROLOGY (2014)
Sorafenib plus all-trans retinoic acid for AML patients with FLT3-ITD and NPM1 mutations
Sarah Guenounou et al.
EUROPEAN JOURNAL OF HAEMATOLOGY (2014)
Lower frequency of NPM1 and FLT3-ITD mutations in a South African adult de novo AML cohort
R. C. Marshall et al.
INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY (2014)
Regulatory role of nucleophosmin during the differentiation of human liver cancer cells
Dong-Hui Xu et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2014)
Loss of Nucleolar Histone Chaperone NPM1 Triggers Rearrangement of Heterochromatin and Synergizes with a Deficiency in DNA Methyltransferase DNMT3A to Drive Ribosomal DNA Transcription
Karl Holmberg Olausson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Mutated NPM1 in patients with acute myeloid leukemia in remission and relapse
Preetesh Jain et al.
LEUKEMIA & LYMPHOMA (2014)
NPM1 Silencing Reduces Tumour Growth and MAPK Signalling in Prostate Cancer Cells
Gaelle Loubeau et al.
PLOS ONE (2014)
The NPM1 Mutation Type Has No Impact on Survival in Cytogenetically Normal AML
Friederike Pastore et al.
PLOS ONE (2014)
Clinical significance of nucleophosmin/B23 and human epidermal growth factor receptor 2/neu expressions in gastric cancers
Fang Zhou et al.
APMIS (2013)
Mutation of NPM1 and FLT3 Genes in Acute Myeloid Leukemia and Their Association with Clinical and Immunophenotypic Features
Pradeep Singh Chauhan et al.
DISEASE MARKERS (2013)
Nucleophosmin 1, upregulated in adenomas and cancers of the colon, inhibits p53-mediated cellular senescence
John C. T. Wong et al.
INTERNATIONAL JOURNAL OF CANCER (2013)
The pathobiology of the oncogenic tyrosine kinase NPM-ALK: a brief update
Raymond Lai et al.
THERAPEUTIC ADVANCES IN HEMATOLOGY (2013)
Age-dependent frequencies of NPM1 mutations and FLT3-ITD in patients with normal karyotype AML (NK-AML)
Friederike Schneider et al.
ANNALS OF HEMATOLOGY (2012)
NPM-MLF1 synergizes with Npm haploinsufficiency to enhance myeloid progenitor activity
W-H Lee et al.
LEUKEMIA (2012)
Amount of bone marrow blasts is strongly correlated to NPM1 and FLT3-ITD mutation rate in AML with normal karyotype
Torsten Haferlach et al.
LEUKEMIA RESEARCH (2012)
Expression of Nucleophosmin/NPM1 correlates with migration and invasiveness of colon cancer cells
Yan Liu et al.
JOURNAL OF BIOMEDICAL SCIENCE (2012)
An Extensive Tumor Array Analysis Supports Tumor Suppressive Role for Nucleophosmin in Breast Cancer
Piia-Riitta Karhemo et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
A Simple Approach to Cancer Therapy Afforded by Multivalent Pseudopeptides That Target Cell-Surface Nucleoproteins
Damien Destouches et al.
CANCER RESEARCH (2011)
Nucleophosmin and its complex network: a possible therapeutic target in hematological diseases
E. Colombo et al.
ONCOGENE (2011)
NPM1/B23: AMultifunctional Chaperone in Ribosome Biogenesis and Chromatin Remodeling
Mikael S. Lindstrom
BIOCHEMISTRY RESEARCH INTERNATIONAL (2011)
The cytoplasmic NPM mutant induces myeloproliferation in a transgenic mouse model
Ke Cheng et al.
BLOOD (2010)
NPM phosphorylation stimulates Cdk1, overrides G2/M checkpoint and increases leukemic blasts in mice
Wei Du et al.
CARCINOGENESIS (2010)
Favorable Prognostic Impact of NPM1 Mutations in Older Patients With Cytogenetically Normal De Novo Acute Myeloid Leukemia and Associated Gene- and MicroRNA-Expression Signatures: A Cancer and Leukemia Group B Study
Heiko Becker et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
Polo-Like Kinase 2-Dependent Phosphorylation of NPM/B23 on Serine 4 Triggers Centriole Duplication
Annekatrin Krause et al.
PLOS ONE (2010)
Nucleophosmin (NPM1) mutations in adult and childhood acute myeloid leukaemia: towards definition of a new leukaemia entity
Rachel Rau et al.
HEMATOLOGICAL ONCOLOGY (2009)
The transcription factor ATF5: role in neurodevelopment and neural tumors
Lloyd A. Greene et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Favorable prognostic impact of NPM1 gene mutations in childhood acute myeloid leukemia, with emphasis on cytogenetically normal AML
I. H. I. M. Hollink et al.
LEUKEMIA (2009)
The prognostic impact of 17p (p53) deletion in 2272 adults with acute myeloid leukemia
H. Seifert et al.
LEUKEMIA (2009)
Lysine 263 residue of NPM/B23 is essential for regulating ATP binding and B23 stability
Joung Woo Choi et al.
FEBS LETTERS (2008)
Structural Consequences of Nucleophosmin Mutations in Acute Myeloid Leukemia
Charles G. Grummitt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Nucleophosmin and its AML-associated mutant regulate c-Myc turnover through Fbw7γ
Paola Bonetti et al.
JOURNAL OF CELL BIOLOGY (2008)
Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases
Chawon Yun et al.
JOURNAL OF CELL BIOLOGY (2008)
Nucleophosmin interacts with HEXIM1 and regulates RNA polymerase II transcription
Meera Gurumurthy et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Nucleophosmin Serves as a Rate-Limiting Nuclear Export Chaperone for the Mammalian Ribosome
Leonard B. Maggi et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
被撤回的出版物: Increase sensitivity to chemotherapeutical agents and cytoplasmatic interaction between NPM leukemic mutant and NF-κB in AML carrying NPM1 mutations (Retracted article. See vol. 24, pg. 1103, 2010)
D. Cilloni et al.
LEUKEMIA (2008)
Nucleophosmin interacts directly with c-Myc and controls c-Myc-induced hyperproliferation and transformation
Zhaoliang Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Influence of nucleophosmin/B23 on DNA binding and transcriptional activity of the androgen receptor in prostate cancer cell
L. Leotoing et al.
ONCOGENE (2008)
Pediatric acute myeloid leukemia with NPM1 mutations is characterized by a gene expression profile with dysregulated HOX gene expression distinct from MLL-rearranged leukemias
C. G. Mullighan et al.
LEUKEMIA (2007)
Analysis of NPM1 gene mutations in Chinese adults with acute myeloid leukemia
Lingzhi Yan et al.
INTERNATIONAL JOURNAL OF HEMATOLOGY (2007)
Absence of nucleophosmin 1 (NPM1) gene mutations in common solid cancers
Eun Goo Jeong et al.
APMIS (2007)
Increased expression of nucleophosmin/B23 in hepatocellular carcinoma and correlation with clinicopathological parameters
J. -P Yun et al.
BRITISH JOURNAL OF CANCER (2007)
Acute myeloid leukemia carrying cytoplasmic/mutated nucleophosmin (NPMc+ AML):: biologic and clinical features
Brunangelo Falini et al.
BLOOD (2007)
NPM1 mutations are more stable than FLT3 mutations during the course of disease in patients with acute myeloid leukemia
Michela Palmisano et al.
HAEMATOLOGICA (2007)
Effects of interphase and mitotic phosphorylation on the mobility and location of nucleolar protein B23
Sandeep S. Negi et al.
JOURNAL OF CELL SCIENCE (2006)
Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML
Brunangelo Falini et al.
BLOOD (2006)
C-terminal nucleophosmin mutations are uncommon in chronic myeloid disorders
Jonathan S. C. Caudill et al.
BRITISH JOURNAL OF HAEMATOLOGY (2006)
Prevalence and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML)
Christian Thiede et al.
BLOOD (2006)
Nucleophosmin is essential for ribosomal protein L5 nuclear export
Yue Yu et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
DNA damage, p14ARF, Nucleophosmin (NPM/B23), and cancer
Ruth A. Gjerset
JOURNAL OF MOLECULAR HISTOLOGY (2006)
Nucleophosmin and human cancer
Mi Jung Lim et al.
CANCER DETECTION AND PREVENTION (2006)
Loading and unloading - Orchestrating centrosome duplication and spindle assembly by Ran/Crm1
AS Budhu et al.
CELL CYCLE (2005)
Nucleophosmin is required for DNA integrity and p19Arf protein stability
E Colombo et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
A proteomics approach for the identification of nucleophosmin and heterogeneous nuclear ribonucleoprotein C1/C2 as chromatin-binding proteins in response to DNA double-strand breaks
SY Lee et al.
BIOCHEMICAL JOURNAL (2005)
Role of nucleophosmin in embryonic development and tumorigenesis
S Grisendi et al.
NATURE (2005)
Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype.
B Falini et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Nucleophosmin/B23, a multifunctional protein that can regulate apoptosis
KQ Ye
CANCER BIOLOGY & THERAPY (2005)
Physical and functional interactions of the Arf tumor suppressor protein with nucleophosmin/B23
D Bertwistle et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
The structural basis for autoinhibition of FLT3 by the juxtamembrane domain
J Griffith et al.
MOLECULAR CELL (2004)
Nek2A kinase regulates the localization of numatrin to centrosome in mitosis
JH Yao et al.
FEBS LETTERS (2004)
Normal and oncogenic FLT3
T Naoe et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2004)
Activation mechanism of the nuclear chaperone nucleoplasmin:: Role of the core domain
S Bañuelos et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
Unique conformation of cancer autoantigen B23 in hepatoma: A mechanism for specificity in the autoimmune response
DB Ulanet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Role of protein kinase CK2 phosphorylation in the molecular chaperone activity of nucleolar protein B23
A Szebeni et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Nucleolar Arf tumor suppressor inhibits ribosomal RNA processing
M Sugimoto et al.
MOLECULAR CELL (2003)
Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation
K Itahana et al.
MOLECULAR CELL (2003)
Tryptophans 286 and 288 in the C-terminal region of protein B23.1 are important for its nucleolar localization
Y Nishimura et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2002)
The role of nucleophosmin in centrosome duplication
M Okuda
ONCOGENE (2002)
The RNA binding activity of a ribosome biogenesis factor, nucleophosmin/B23, is modulated by phosphorylation with a cell cycle-dependent kinase and by association with its subtype
M Okuwaki et al.
MOLECULAR BIOLOGY OF THE CELL (2002)
Nucleophosmin/B23 is a target of CDK2/Cyclin E in centrosome duplication
M Okuda et al.
CELL (2000)
Share Paper
