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Oxidative Stress Caused by Ozone Exposure Induces Loss of Brain Repair in the Hippocampus of Adult Rats
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HUMAN MOLECULAR GENETICS (2009)
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Chronic Exposure to the Herbicide, Atrazine, Causes Mitochondrial Dysfunction and Insulin Resistance
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Chronic Neuron-Specific Tumor Necrosis Factor-Alpha Expression Enhances the Local Inflammatory Environment Ultimately Leading to Neuronal Death in 3xTg-AD Mice
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Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease
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Increased systemic and brain cytokine production and neuroinflammation by endotoxin following ethanol treatment
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CYP51: A Major Drug Target in the Cytochrome P450 Superfamily
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Apolipoprotein E and cholesterol in aging and disease in the brain
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FUTURE LIPIDOLOGY (2008)
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Mitochondrial Oxidative Stress Causes Hyperphosphorylation of Tau
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Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment
S. W. Scheff et al.
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Accumulation of pathological tau species and memory loss in a conditional model of tauopathy
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Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
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Aβ40 inhibits amyloid deposition in vivo
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I. Bjorkhem
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A century of Alzheimer's disease
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Effect of tri-o-cresyl phosphate on cytoskeleton in human neuroblastoma SK-N-SH cell
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Regulation of Intracellular Accumulation of Mutant Huntingtin by Beclin 1
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24(S)-hydroxycholesterol participates in a liver X receptor-controlled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux
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Increased levels of granular tau oligomers: An early sign of brain aging and Alzheimer's disease
S Maeda et al.
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Oxidative stress, mitochondrial permeability transition, and cell death in Cu-exposed trout hepatocytes
G Krumschnabel et al.
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Tau suppression in a neurodegenerative mouse model improves memory function
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Glucose metabolism and Alzheimer's disease
D Schubert
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Human apoE4-targeted replacement mice display synaptic deficits in the absence of neuropathology
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Oxidative imbalance in Alzheimer's disease
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Neuron-specific apolipoprotein E4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice
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Role for neuronal insulin resistance in neurodegenerative diseases
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease
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No evidence for loss of hippocampal neurons in non-Alzheimer dementia patients
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Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease
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A mitochondrial cascade hypthesis for sporadic Alzheimer's disease
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Tau phosphorylation in neuronal cell function and dysfunction
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Induction of inflammatory mediators and microglial activation in mice transgenic for mutant human P301S tau protein
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Increased tau phosphorylation in apolipoprotein E4 transgenic mice is associated with activation of extracellular signal-regulated kinase - Modulation by zinc
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Brain cholesterol:: Long secret life behind a barrier
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Using gene expression profiling to identify the molecular basis of the synergistic actions of hepatocyte growth factor and vascular endothelial growth factor in human endothelial cells
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Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice
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Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation
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Triple-transgenic model of Alzheimer's disease with plaques and tangles:: Intracellular Aβ and synaptic dysfunction
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Cholesterol homeostasis and function in neurons of the central nervous system
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Proteasome inhibition by paired helical filament-tau in brains of patients with Alzheimer's disease
S Keck et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease
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Stage-dependent and sector-specific neuronal loss in hippocampus during Alzheimer's disease
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Neuron loss from the hippocampus of Alzheimer's disease exceeds extracellular neurofibrillary tangle formation
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ACTA NEUROPATHOLOGICA (2002)
Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
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Apolipoprotein E4 inhibits, and apolipoprotein E3 promotes neurit eoutgrowth in cultured adult mouse cortical neurons through the low-density lipoprotein receptor-related protein
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PP2A mRNA expression is quantitatively decreased in Alzheimer's disease hippocampus
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Oxidative regulation of fatty acid-induced tau polymerization
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Oxidative stress and Ca2+ influx upregulate calpain and induce apoptosis in PC12 cells
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Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice
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