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Update on pregnancy in Takayasu arteritis-A narrative review

Journal

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
Volume 24, Issue 6, Pages 758-765

Publisher

WILEY
DOI: 10.1111/1756-185X.14109

Keywords

aortoarteritis; fertility; obstetrical outcomes; pregnancy; Takayasu arteritis

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Takayasu arteritis is a chronic vasculitis that affects pregnant women and their babies, with conflicting data on fertility effects but generally unaffected outcomes. Disease activity of TA typically remains stable or decreases during pregnancy, but fetomaternal complications can still occur, highlighting the importance of controlling the disease before conception.
Takayasu arteritis (TA) is a chronic, idiopathic large-vessel vasculitis that affects women of reproductive age, and has significant maternal and fetal implications. Although there are contrasting data on the effect of TA on fertility, most studies have shown that fertility outcomes remain unaffected. The disease activity of TA usually either remains stable or decreases during pregnancy. The important fetomaternal complications are maternal hypertension, pre-eclampsia, prematurity, and intrauterine growth restriction. To reduce maternal and fetal morbidity, controlling the disease before conception is important. This review article discusses the various implications, challenges, and medical and endovascular management of TA during pregnancy.

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