4.7 Article

Nose to brain delivery of tailored clozapine nanosuspension stabilized using (+)-alpha-tocopherol polyethylene glycol 1000 succinate: Optimization and in vivo pharmacokinetic studies

Related references

Note: Only part of the references are listed.
Article Pharmacology & Pharmacy

Oral bioavailability improvement of felodipine using tailored microemulsion: Surface science, ex vivo and in vivo studies

Akshay R. Koli et al.

Summary: Felodipine, a calcium channel blocker with low oral bioavailability, was studied using microemulsion to improve drug permeability in the intestine. Research showed that a stable microemulsion can significantly enhance the oral bioavailability of Felodipine through improved drug stability and permeability.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

Article Pharmacology & Pharmacy

Tailored Doxycycline Hyclate Loaded In Situ Gel for the Treatment of Periodontitis: Optimization, In Vitro Characterization, and Antimicrobial Studies

Ketan M. Ranch et al.

Summary: The study successfully developed tailored doxycycline hyclate laden in situ gel for periodontitis treatment, which achieved sustained drug release above MIC, easy administration, and localization in the periodontal cavity. Optimization was conducted using Box-Behnken design with minimal polymers to meet the required characteristics for effective drug delivery.

AAPS PHARMSCITECH (2021)

Article Pharmacology & Pharmacy

Topical delivery of cyclosporine loaded tailored niosomal nanocarriers for improved skin penetration and deposition in psoriasis: Optimization, ex vivo and animal studies

Sonia S. Pandey et al.

Summary: The study successfully improved the penetration and deposition of cyclosporine in skin tissue for effective treatment of psoriasis by using niosomes.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2021)

Article Pharmacology & Pharmacy

Nose to brain delivery of rotigotine loaded chitosan nanoparticles in human SH-SY5Y neuroblastoma cells and animal model of Parkinson's disease

Subrat K. Bhattamisra et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

Review Chemistry, Multidisciplinary

Stimuli-responsive In situ gelling system for nose-to-brain drug delivery

Mukta Agrawal et al.

JOURNAL OF CONTROLLED RELEASE (2020)

Article Pharmacology & Pharmacy

Bioavailability enhancement of repaglinide from transdermally applied nanostructured lipid carrier gel: Optimization, in vitro and in vivo studies

Sonia S. Pandey et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2020)

Article Pharmacology & Pharmacy

Nose-to-brain delivery of levetiracetam after intranasal administration to mice

Joana Goncalves et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

Article Chemistry, Multidisciplinary

Increased Nose-to-Brain Delivery of Melatonin Mediated by Polycaprolactone Nanoparticles for the Treatment of Glioblastoma

Edilson Ribeiro de Oliveira Junior et al.

PHARMACEUTICAL RESEARCH (2019)

Review Chemistry, Multidisciplinary

Nanosystems in nose-to-brain drug delivery: A review of non-clinical brain targeting studies

Patricia C. Pires et al.

JOURNAL OF CONTROLLED RELEASE (2018)

Review Pharmacology & Pharmacy

Nano-carrier enabled drug delivery systems for nose to brain targeting for the treatment of neurodegenerative disorders

Shadab Md et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2018)

Article Pharmacology & Pharmacy

Design and Evaluation of Novel Solid Self-Nanodispersion Delivery System for Andrographolide

Junnan Xu et al.

AAPS PHARMSCITECH (2017)

Review Pharmacology & Pharmacy

Application of quality by design in the current drug development

Lan Zhang et al.

ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2017)

Article Pharmacology & Pharmacy

Brain targeted nanoparticulate drug delivery system of rasagiline via intranasal route

Deepti Mittal et al.

DRUG DELIVERY (2016)

Article Pharmacology & Pharmacy

Nose-To-Brain Delivery of PLGA-Diazepam Nanoparticles

Deepak Sharma et al.

AAPS PHARMSCITECH (2015)

Review Chemistry, Medicinal

Nanoneurotherapeutics approach intended for direct nose to brain delivery

Md Shadab et al.

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2015)

Article Pharmacology & Pharmacy

Impairment of left ventricular function early in treatment with clozapine: a preliminary study

Martina Curto et al.

INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY (2015)

Review Pharmacology & Pharmacy

Nanotechnology-mediated nose to brain drug delivery for Parkinson's disease: a mini review

Abhijeet D. Kulkarni et al.

JOURNAL OF DRUG TARGETING (2015)

Article Biochemistry & Molecular Biology

Preparation and evaluation of a buflomedil hydrochloride niosomal patch for transdermal delivery

Nida Akhtar et al.

JOURNAL OF LIPOSOME RESEARCH (2015)

Review Pharmacology & Pharmacy

Insights into direct nose to brain delivery: current status and future perspective

Deepti Mittal et al.

DRUG DELIVERY (2014)

Article Biochemistry & Molecular Biology

Donepezil nanosuspension intended for nose to brain targeting: In vitro and in vivo safety evaluation

Bhavna et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2014)

Review Pharmacology & Pharmacy

Direct nose to brain drug delivery via integrated nerve pathways bypassing the blood-brain barrier: an excellent platform for brain targeting

Chandrakantsing Vijaysing Pardeshi et al.

EXPERT OPINION ON DRUG DELIVERY (2013)

Article Nanoscience & Nanotechnology

Nose to Brain Targeting Potential of a Chitosan-Coated Nano-Formulation: Pharmacodynamic and Pharmacoscintigraphic Evaluation

Gulam Mustafa et al.

SCIENCE OF ADVANCED MATERIALS (2013)

Review Pharmacology & Pharmacy

Physicochemical and physiological considerations for efficient nose-to-brain targeting

Shiv Bahadur et al.

EXPERT OPINION ON DRUG DELIVERY (2012)

Article Psychology, Clinical

Life-threatening clozapine-induced gastrointestinal hypomotility: An analysis of 102 cases

Susanna E. Palmer et al.

JOURNAL OF CLINICAL PSYCHIATRY (2008)

Letter Psychiatry

Clozapine-induced agranulocytosis after 11 years of treatment

K Sedky et al.

AMERICAN JOURNAL OF PSYCHIATRY (2005)

Review Pharmacology & Pharmacy

Biotransformation of post-clozapine antipsychotics - Pharmacological implications

S Caccia

CLINICAL PHARMACOKINETICS (2000)