Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22, Issue 9, Pages -Publisher
MDPI
DOI: 10.3390/ijms22094733
Keywords
choline; ocular disease; dry eye syndrome; retina; diabetic retinopathy; glaucoma
Funding
- National Research Foundation (NRF) - Korea government [NRF2018R1A2B6002251]
- Hallym Research Fund
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Choline is essential for maintaining the structure and function of cells in humans, particularly in eye health and disease. Choline deficiency is associated with eye diseases, while supplementation of choline may be effective in treating these conditions.
Choline is essential for maintaining the structure and function of cells in humans. Choline plays an important role in eye health and disease. It is a precursor of acetylcholine, a neurotransmitter of the parasympathetic nervous system, and it is involved in the production and secretion of tears by the lacrimal glands. It also contributes to the stability of the cells and tears on the ocular surface and is involved in retinal development and differentiation. Choline deficiency is associated with retinal hemorrhage, glaucoma, and dry eye syndrome. Choline supplementation may be effective for treating these diseases.
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