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ANNUAL REVIEW OF MEDICINE (2009)
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Regulation of Drosophila embryonic tracheogenesis by dVHL and hypoxia
Nathan T. Mortimer et al.
DEVELOPMENTAL BIOLOGY (2009)
Oxidation promotes insertion of the CLIC1 chloride intracellular channel into the membrane
Sophia C. Goodchild et al.
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2009)
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HUMAN MOLECULAR GENETICS (2009)
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MOLECULAR AND CELLULAR BIOLOGY (2009)
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CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2008)
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pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation
Ian J. Frew et al.
EMBO JOURNAL (2008)
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Xiaogang Li et al.
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Carsten Kempkensteffen et al.
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Bradley K. Yoder
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R. Houston Thompson et al.
CLINICAL CANCER RESEARCH (2007)
Everolimus retards cyst growth and preserves kidney function in a rodent model for polycystic kidney disease
Ming Wu et al.
KIDNEY & BLOOD PRESSURE RESEARCH (2007)
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Formation of primary cilia in the renal epithelium is regulated by the von Hippel-Lindau tumor suppressor protein
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Loss of cell polarity drives tumor growth and invasion through JNK activation in Drosophila
Tatsushi Igaki et al.
CURRENT BIOLOGY (2006)
Melatonin as antioxidant, geroprotector and anticarcinogen
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BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2006)
The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease
JM Shillingford et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
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VH Haase
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Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD)
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Calcium restores a normal proliferation phenotype in human polycystic kidney disease epithelial cells
Tamio Yamaguchi et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)
Renal-cell carcinoma
HT Cohen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis
AG Kramer-Zucker et al.
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Downregulation of Smac/DIABLO expression in renal cell carcinoma and its prognostic significance
Y Mizutani et al.
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Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease
YX Tao et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2005)
Differential targeting of two distinct SWI/SNF-related Drosophila chromatin-remodeling complexes
L Mohrmann et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
The intracellular chloride ion channel protein CLIC1 undergoes a redox-controlled structural transition
DR Littler et al.
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Calcium restriction allows cAMP activation of the B-Raf/ERK pathway, switching cells to a cAMP-dependent growth-stimulated phenotype
T Yamaguchi et al.
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Strict regulation of CAIXG250/MN by HIF-1α in clear cell renal cell carcinoma
K Grabmaier et al.
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The human protein Hugl-1 substitutes for Drosophila Lethal giant larvae tumour suppressor function in vivo
D Grifoni et al.
ONCOGENE (2004)
mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E
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Disturbed balance of expression between XIAP and Smac/DIABLO during tumour progression in renal cell carcinomas
Y Yan et al.
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Function-informed transcriptome analysis of Drosophila renal tubule
J Wang et al.
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Drosophila awd, the homolog of human nm23, regulates FGF receptor levels and functions synergistically with shi/dynamin during tracheal development
V Dammai et al.
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SCIENCE (2003)
scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila
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H Anderson et al.
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
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WM Linehan et al.
JOURNAL OF UROLOGY (2003)
Branching morphogenesis of the Drosophila tracheal system
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ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY (2003)
The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia
BK Yoder et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2002)
Regulation of hypoxia-inducible factor 1α expression and function by the mammalian target of rapamycin
CC Hudson et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Wengen, a member of the Drosophila tumor necrosis factor receptor superfamily, is required for Eiger signaling
H Kanda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Analysis of kidney tumors by comparative genomic hybridization and conventional cytogenetics
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Evolution of TNF signaling mechanisms:: JNK-dependent apoptosis triggered by Eiger, the Drosophila homolog of the TNF superfamily
E Moreno et al.
CURRENT BIOLOGY (2002)
Epithelial-specific Cre/lox recombination in the developing kidney and genitourinary tract
XL Shao et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2002)
Eiger, a TNF superfamily ligand that triggers the Drosophila JNK pathway
T Igaki et al.
EMBO JOURNAL (2002)
Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease
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CURRENT BIOLOGY (2002)
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Interleukin-6, tumour necrosis factor α and interleukin-1β in patients with renal cell carcinoma
N Yoshida et al.
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Developmental control of blood cell migration by the Drosophila VEGF pathway
NK Cho et al.
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Homophila: human disease gene cognates in Drosophila
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NUCLEIC ACIDS RESEARCH (2002)
c-Myc regulates mammalian body size by controlling cell number but not cell size
A Trumpp et al.
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