Related references
Note: Only part of the references are listed.The Dysregulation of OGT/OGA Cycle Mediates Tau and APP Neuropathology in Down Syndrome
Ilaria Zuliani et al.
NEUROTHERAPEUTICS (2021)
Chronic hyperglycemia induces tau hyperphosphorylation by downregulating OGT-involved O-GlcNAcylation in vivo and in vitro
Rong Huang et al.
BRAIN RESEARCH BULLETIN (2020)
APP Maturation and Intracellular Localization Are Controlled by a Specific Inhibitor of 37/67 kDa Laminin-1 Receptor in Neuronal Cells
Antaripa Bhattacharya et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
O-GlcNAcylation as a Therapeutic Target for Alzheimer's Disease
Jinsu Park et al.
NEUROMOLECULAR MEDICINE (2020)
Insulin mediated novel therapies for the treatment of Alzheimer's disease
Sunil Kumar Dubey et al.
LIFE SCIENCES (2020)
Inhibition of 37/67kDa Laminin-1 Receptor Restores APP Maturation and Reduces Amyloid-β in Human Skin Fibroblasts from Familial Alzheimer's Disease
Antaripa Bhattacharya et al.
JOURNAL OF PERSONALIZED MEDICINE (2020)
The Medial Septum Is Insulin Resistant in the AD Presymptomatic Phase: Rescue by Nerve Growth Factor-Driven IRS1 Activation
Valentina Sposato et al.
MOLECULAR NEUROBIOLOGY (2019)
Biliverdin Reductase-A Mediates the Beneficial Effects of Intranasal Insulin in Alzheimer Disease
Eugenio Barone et al.
MOLECULAR NEUROBIOLOGY (2019)
Structural characterization of the O-GlcNAc cycling enzymes: insights into substrate recognition and catalytic mechanisms
Cassandra M. Joiner et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2019)
Targeting Mitochondria in Alzheimer Disease: Rationale and Perspectives
Chiara Lanzillotta et al.
CNS DRUGS (2019)
High-Fat Diet Induces Neuroinflammation and Mitochondrial Impairment in Mice Cerebral Cortex and Synaptic Fraction
Gina Cavaliere et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2019)
Therapeutic potential of rescuing protein O-GlcNAcylation in tau-related pathologies
Fabio Di Domenico et al.
EXPERT REVIEW OF NEUROTHERAPEUTICS (2019)
Nutrient regulation of signaling and transcription
Gerald W. Hart
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Acute increases in O-GlcNAc indirectly impair mitochondrial bioenergetics through dysregulation of LonP1-mediated mitochondrial protein complex turnover
JaLessa N. Wright et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2019)
Global aetiology and epidemiology of type 2 diabetes mellitus and its complications
Yan Zheng et al.
NATURE REVIEWS ENDOCRINOLOGY (2018)
Pharmacological Inhibition of O-GIcNAcase Enhances Autophagy in Brain through an mTOR-Independent Pathway
Yanping Zhu et al.
ACS CHEMICAL NEUROSCIENCE (2018)
O-G1cNAcylation and neuronal energy status: Implications for Alzheimer's disease
Tiffany S. Pinho et al.
AGEING RESEARCH REVIEWS (2018)
Melatonin prevents memory impairment induced by high-fat diet: Role of oxidative stress
Karem H. Alzoubi et al.
BEHAVIOURAL BRAIN RESEARCH (2018)
Proteomic identification of altered protein O-GlcNAcylation in a triple transgenic mouse model of Alzheimer's disease
Antonella Tramutola et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2018)
High-Fat Diet Causes Mitochondrial Dysfunction as a Result of Impaired ADP Sensitivity
Paula M. Miotto et al.
DIABETES (2018)
Crosstalk between phosphorylation and O-GlcNAcylation: friend or foe
Saar A. M. van der Laarse et al.
FEBS JOURNAL (2018)
AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation
Roselle Gelinas et al.
NATURE COMMUNICATIONS (2018)
A high-fat diet impairs mitochondrial biogenesis, mitochondrial dynamics, and the respiratory chain complex in rat myocardial tissues
Dan Chen et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2018)
Rapid and reversible impairment of episodic memory by a high-fat diet in mice
Fiona H. McLean et al.
SCIENTIFIC REPORTS (2018)
Attempt to Untangle the Prion-Like Misfolding Mechanism for Neurodegenerative Diseases
Daniela Sarnataro
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Chronic O-GlcNAcylation and Diabetic Cardiomyopathy: The Bitterness of Glucose
Simon Ducheix et al.
FRONTIERS IN ENDOCRINOLOGY (2018)
Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome
Antonella Tramutola et al.
TRANSLATIONAL NEURODEGENERATION (2018)
GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis
Darya Zibrova et al.
BIOCHEMICAL JOURNAL (2017)
Mitochondria and Synaptic Plasticity in the Mature and Aging Nervous System
Vyara Todorova et al.
CURRENT NEUROPHARMACOLOGY (2017)
Glucose Transporters in Brain: In Health and in Alzheimer's Disease
Leszek Szablewski
JOURNAL OF ALZHEIMERS DISEASE (2017)
Sustained O-GlcNAcylation reprograms mitochondrial function to regulate energy metabolism
Ee Phie Tan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Protein O-GlcNAcylation: emerging mechanisms and functions
Xiaoyong Yang et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)
Inhibition of hippocampal long-term potentiation by high-fat diets: is it related to an effect of palmitic acid involving glycogen synthase kinase-3?
Ana Contreras et al.
NEUROREPORT (2017)
Loss of Leptin-Induced Modulation of Hippocampal Synaptic Trasmission and Signal Transduction in High-Fat Diet-Fed Mice
Marco Mainardi et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2017)
Brain insulin resistance impairs hippocampal synaptic plasticity and memory by increasing GluA1 palmitoylation through FoxO3a
Matteo Spinelli et al.
NATURE COMMUNICATIONS (2017)
The Triangle of Death in Alzheimer's Disease Brain: The Aberrant Cross-Talk Among Energy Metabolism, Mammalian Target of Rapamycin Signaling, and Protein Homeostasis Revealed by Redox Proteomics
Fabio Di Domenico et al.
ANTIOXIDANTS & REDOX SIGNALING (2017)
High fat diet induces brain insulin resistance and cognitive impairment in mice
Vishal Kothari et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2017)
O-GlcNAcylation: A regulator of tau pathology and neurodegeneration
Cheng-Xin Gong et al.
ALZHEIMERS & DEMENTIA (2016)
Nucleocytoplasmic human O-GlcNAc transferase is sufficient for O-GlcNAcylation of mitochondrial proteins
Riccardo Trapannone et al.
BIOCHEMICAL JOURNAL (2016)
Aberrant protein phosphorylation in Alzheimer disease brain disturbs pro-survival and cell death pathways
M. Perluigi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2016)
Impairment of biliverdin reductase-A promotes brain insulin resistance in Alzheimer disease: A new paradigm
Eugenio Barone et al.
FREE RADICAL BIOLOGY AND MEDICINE (2016)
The regulatory roles of O-GlcNAcylation in mitochondrial homeostasis and metabolic syndrome
Lin Zhao et al.
FREE RADICAL RESEARCH (2016)
An Update on Type 2 Diabetes Mellitus as a Risk Factor for Dementia
Wei Li et al.
JOURNAL OF ALZHEIMERS DISEASE (2016)
Evidence for an imbalance between tau O-GlcNAcylation and phosphorylation in the hippocampus of a mouse model of Alzheimer's disease
Eleonora Gatta et al.
PHARMACOLOGICAL RESEARCH (2016)
An Overview of Murine High Fat Diet as a Model for Type 2 Diabetes Mellitus
Ahlke Heydemann
JOURNAL OF DIABETES RESEARCH (2016)
Alzheimer's disease and type 2 diabetes-related alterations in brain mitochondria, autophagy and synaptic markers
Cristina Carvalho et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2015)
High-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to Alzheimer disease pathology in rodents
Dmitry Petrov et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2015)
O-GlcNAcomic Profiling Identifies Widespread O-Linked β-N-Acetylglucosamine Modification (O-GlcNAcylation) in Oxidative Phosphorylation System Regulating Cardiac Mitochondrial Function
Junfeng Ma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Cognitive function in patients with diabetes mellitus: guidance for daily care
Paula S. Koekkoek et al.
LANCET NEUROLOGY (2015)
Leptin resistance in diet-induced obesity: the role of hypothalamic inflammation
K. C. G. de Git et al.
OBESITY REVIEWS (2015)
Effects of high-fat diet exposure on learning & memory
Zachary A. Cordner et al.
PHYSIOLOGY & BEHAVIOR (2015)
Aberrant insulin signaling in Alzheimer's disease: current knowledge
Gaurav Bedse et al.
FRONTIERS IN NEUROSCIENCE (2015)
Role of O-GlcNAcylation in nutritional sensing, insulin resistance and in mediating the benefits of exercise
Jason P. Myslicki et al.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM (2014)
Insulin, incretins and other growth factors as potential novel treatments for Alzheimer's and Parkinson's diseases
Christian Hoelscher
BIOCHEMICAL SOCIETY TRANSACTIONS (2014)
Elevated risk of type 2 diabetes for development of Alzheimer disease: A key role for oxidative stress in brain
D. Allan Butterfield et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2014)
Impairment of hippocampal-dependent memory induced by juvenile high-fat diet intake is associated with enhanced hippocampal inflammation in rats
Chloe Boitard et al.
BRAIN BEHAVIOR AND IMMUNITY (2014)
Nutrient Regulation of Signaling, Transcription, and Cell Physiology by O-GlcNAcylation
Stephan Hardiville et al.
CELL METABOLISM (2014)
Altering O-Linked β-N-Acetylglucosamine Cycling Disrupts Mitochondrial Function
Ee Phie Tan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Cross-talk between Two Essential Nutrient-sensitive Enzymes O-GlcNAc TRANSFERASE ( OGT) AND AMP-ACTIVATED PROTEIN KINASE ( AMPK)
John W. Bullen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
The Emerging Link between O-GlcNAc and Alzheimer Disease
Yanping Zhu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Nutrient-driven O-GlcNAc cycling - think globally but act locally
Katryn R. Harwood et al.
JOURNAL OF CELL SCIENCE (2014)
Short-term high-fat-and-fructose feeding produces insulin signaling alterations accompanied by neurite and synaptic reduction and astroglial activation in the rat hippocampus
Erika Calvo-Ochoa et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2014)
High-fat diet increases tau expression in the brain of T2DM and AD mice independently of peripheral metabolic status
Mari Takalo et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2014)
Pharmacological inhibition of O-GlcNAcase (OGA) prevents cognitive decline and amyloid plaque formation in bigenic tau/APP mutant mice
Scott A. Yuzwa et al.
MOLECULAR NEURODEGENERATION (2014)
High fat diet produces brain insulin resistance, synaptodendritic abnormalities and altered behavior in mice
Steven E. Arnold et al.
NEUROBIOLOGY OF DISEASE (2014)
Brain Aging and AD-Like Pathology in Streptozotocin-Induced Diabetic Rats
Jian-Qin Wang et al.
JOURNAL OF DIABETES RESEARCH (2014)
Protein O-GlcNAcylation in diabetes and diabetic complications
Junfeng Ma et al.
EXPERT REVIEW OF PROTEOMICS (2013)
Many Faces of Mitochondrial Uncoupling During Age: Damage or Defense?
Francesco Bellanti et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2013)
Discovery and Confirmation of O-GlcNAcylated Proteins in Rat Liver Mitochondria by Combination of Mass Spectrometry and Immunological Methods
Weiqian Cao et al.
PLOS ONE (2013)
Cracking the O-GlcNAc code in metabolism
Hai-Bin Ruan et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2013)
High-fat diets induce changes in hippocampal glutamate metabolism and neurotransmission
Ismael Valladolid-Acebes et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2012)
Glutamatergic alterations and mitochondrial impairment in a murine model of Alzheimer disease
Tommaso Cassano et al.
NEUROBIOLOGY OF AGING (2012)
The effects of a high-energy diet on hippocampal-dependent discrimination performance and blood-brain barrier integrity differ for diet-induced obese and diet-resistant rats
Terry L. Davidson et al.
PHYSIOLOGY & BEHAVIOR (2012)
Mapping O-GlcNAc modification sites on tau and generation of a site-specific O-GlcNAc tau antibody
Scott A. Yuzwa et al.
AMINO ACIDS (2011)
O-GlcNAcylation increases non-amyloidogenic processing of the amyloid-β precursor protein (APP)
Kristin T. Jacobsen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Dementia, Diabetes, Alzheimer's Disease, and Insulin Resistance in the Brain: Progress, Dilemmas, New Opportunities, and a Hypothesis to Tackle Intersecting Epidemics
Rodrigo O. Kuljis et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
Increased Expression of β-N-Acetylglucosaminidase in Erythrocytes From Individuals With Pre-diabetes and Diabetes
Kyoungsook Park et al.
DIABETES (2010)
Regulation of Insulin Receptor Substrate 1 (IRS-1)/AKT Kinase-mediated Insulin Signaling by O-Linked β-N-Acetylglucosamine in 3T3-L1 Adipocytes
Stephen A. Whelan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Insulin deficiency exacerbates cerebral amyloidosis and behavioral deficits in an Alzheimer transgenic mouse model
Xu Wang et al.
MOLECULAR NEURODEGENERATION (2010)
The economic impact of obesity in the United States
Ross A. Hammond et al.
DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY (2010)
Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease
Fei Liu et al.
BRAIN (2009)
Modifiers of cognitive function and brain structure in middle-aged and elderly individuals with type 2 diabetes mellitus
Hannah Bruehl et al.
BRAIN RESEARCH (2009)
AMP-activated protein kinase phosphorylates glutamine : fructose-6-phosphate amidotransferase 1 at Ser243 to modulate its enzymatic activity
Satoshi Eguchi et al.
GENES TO CELLS (2009)
Increased Enzymatic O-GlcNAcylation of Mitochondrial Proteins Impairs Mitochondrial Function in Cardiac Myocytes Exposed to High Glucose
Yong Hu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
O-GlcNAc Protein Modification in Cancer Cells Increases in Response to Glucose Deprivation through Glycogen Degradation
Jeong Gu Kang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Brain insulin, energy and glucose homeostasis; genes, environment and metabolic pathologies
Kyriaki Gerozissis
EUROPEAN JOURNAL OF PHARMACOLOGY (2008)
Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease
Ying Liu et al.
FEBS LETTERS (2008)
AMP-activated protein kinase and p38 MAPK activate O-GlcNAcylation of neuronal proteins during glucose deprivation
Win D. Cheung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Regulation of the O-linked β-N-acetylglucosamine transferase by insulin signaling
Stephen A. Whelan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
Xiaoyong Yang et al.
NATURE (2008)
Cross-talk between GlcNAcylation and phosphorylation:: Site-specific phosphorylation dynamics in response to globally elevated O-GlcNAc
Zihao Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
O-GlcNAc modification of transcription factors, glucose sensing and glucotoxicity
Tarik Issad et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2008)
O-GlcNAc modification in diabetes and Alzheimer's disease
Wagner B. Dias et al.
MOLECULAR BIOSYSTEMS (2007)
High-fat diets, insulin resistance and declining cognitive function
CE Greenwood et al.
NEUROBIOLOGY OF AGING (2005)
O-GlcNAc modific ation on IRS-1 and Akt2 by PUGNAc inhibits their phosphorylation and induces insulin resistance in rat primary adipocytes
SY Park et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2005)
Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications
P Bubber et al.
ANNALS OF NEUROLOGY (2005)
Prolonged incubation in PUGNAc results in increased protein O-linked glycosylation and insulin resistance in rat skeletal muscle
EB Arias et al.
DIABETES (2004)
O-GlcNAcylation regulates phosphorylation of tau: A mechanism involved in Alzheimer's disease
F Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Evidence of a balance between phosphorylation and O-GlcNAc glycosylation of Tau proteins -: a role in nuclear localization
T Lefebvre et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2003)
Dynamic interplay between O-glycosylation and O-phosphorylation of nucleocytoplasmic proteins -: Alternative glycosylation/phosphorylation of Thr-58, a known mutational hot spot of c-Myc in lymphomas, is regulated by mitogens
K Kamemura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bε at Ser539 and the microtubule-associated protein tau at Thr212:: potential role for DYRK as a glycogen synthase kinase 3-priming kinase
YL Woods et al.
BIOCHEMICAL JOURNAL (2001)
Share Paper
