Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22, Issue 6, Pages -Publisher
MDPI
DOI: 10.3390/ijms22062993
Keywords
gut microbiota; obesity; gut– brain axis; dysbiosis; satiety
Funding
- Novo Nordisk Foundation CAMIT grant 2018
- ZonMw VICI [09150182010020]
Ask authors/readers for more resources
Obesity, a global epidemic, is associated with microbial dysbiosis. Research indicates that the gut microbiota and its metabolites have an impact on human brain and behavior. Future treatment strategies for obesity may target the gut microbiota.
Interaction between the gut and the brain is essential for energy homeostasis. In obesity, this homeostasis is disrupted, leading to a positive energy balance and weight gain. Obesity is a global epidemic that affects individual health and strains the socioeconomic system. Microbial dysbiosis has long been reported in obesity and obesity-related disorders. More recent literature has focused on the interaction of the gut microbiota and its metabolites on human brain and behavior. Developing strategies that target the gut microbiota could be a future approach for the treatment of obesity. Here, we review the microbiota-gut-brain axis and possible therapeutic options.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available