Small Intestinal Bacterial Overgrowth

reside in the colon. As one of the earliest descriptions of blind-loop syndrome in 1939, wherein macrocytic anemia and steatorrhea were noted in patients with altered postsurgical gastrointestinal (GI) tract anatomy,1 the concept of SIBO has undergone significant change and challenges in light of further clinical studies and advances in technology that have increased our understanding of the gut microbiome. The diagnosis and overall conception of SIBO has, thereby, become mired in uncertainty and controversy, as there remains a lack of consensus or gold standard for diagnosis. The purpose of this review is to discuss current views on the pathophysiology,

Automated summary

The concept of SIBO has undergone significant changes and challenges, with uncertainty and controversy surrounding its diagnosis. This review aims to discuss the current pathophysiology of SIBO.