Journal
FEBS JOURNAL
Volume 288, Issue 8, Pages 2458-2460Publisher
WILEY
DOI: 10.1111/febs.15839
Keywords
arrestins; biased agonism; cellular signaling; desensitization; GPCRs
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Funding
- Senior Fellowship of the DBT Wellcome Trust India Alliance [IA/S/20/1/504916]
- SERB National Facility for cryo-Electron Microscopy at IIT Kanpur [IPA/2020/000405]
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This Special Issue of The FEBS Journal presents a series of review articles focusing on recent developments in the field of GPCR biology, with particular emphasis on novel paradigms of their activation, signaling, and regulation. These articles cover a wide range of cellular, physiological, and structural aspects related to GPCRs and their interactions with signal transducers, allosteric modulation, and emerging technologies for studying receptor signaling and regulation.
This Special Issue of The FEBS Journal brings together a set of review articles focused on recent developments in the field of GPCR biology, with particular emphasis on novel paradigms of their activation, signaling, and regulation. These articles cover a broad repertoire of cellular, physiological, and structural aspects ranging from the interaction of GPCRs with their signal transducers, allosteric modulation of these receptors with therapeutic implications, and emerging technologies aimed to probe critical aspects of receptor signaling and regulation.
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