Journal
EXERCISE AND SPORT SCIENCES REVIEWS
Volume 49, Issue 3, Pages 188-196Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1249/JES.0000000000000251
Keywords
obesity; exercise; arterial function; perivascular adipose tissue; exercise training
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Funding
- National Institute of General Medical Sciences of the National Institutes of Health [U54GM104942, 5P20GM109098]
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Obesity is often accompanied by dysfunction of adipose tissue and arteries. Perivascular adipose tissue (PVAT) plays a crucial role in regulating arterial health, and exercise training has been shown to positively impact PVAT, thereby improving arterial health in diseased populations.
Adipose tissue and arterial dysfunction are common in the obese state. Perivascular adipose tissue (PVAT) plays an important role in mediating arterial health, and with obesity, the PVAT dysfunction negatively affects arterial health. Exercise training exerts direct and beneficial effects on PVAT, providing an additional and novel pathway by which exercise can improve arterial health in diseased populations.
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