4.6 Letter

Inhaled corticosteroids downregulate SARS-CoV-2-related genes in COPD: results from a RCT

Related references

Note: Only part of the references are listed.
Article Allergy

Inhaled corticosteroids downregulate the SARS-CoV-2 receptor ACE2 in COPD through suppression of type I interferon

Lydia J. Finney et al.

Summary: Inhaled corticosteroids (ICS) treatment in COPD patients reduces the expression of ACE2, the entry receptor for SARS-CoV-2, potentially contributing to a reduced risk of COVID-19 infection in these patients.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2021)

Article Critical Care Medicine

Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial

Sanjay Ramakrishnan et al.

Summary: The study found that early administration of inhaled budesonide reduced the likelihood of needing urgent medical care and accelerated recovery time in patients with early COVID-19.

LANCET RESPIRATORY MEDICINE (2021)

Letter Respiratory System

ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19

Janice M. Leung et al.

EUROPEAN RESPIRATORY JOURNAL (2020)

Article Respiratory System

Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis

Wei-jie Guan et al.

EUROPEAN RESPIRATORY JOURNAL (2020)

Letter Critical Care Medicine

SARS-CoV-2 receptor ACE2 gene expression and RAAS inhibitors

Stephen Milne et al.

LANCET RESPIRATORY MEDICINE (2020)

Review Immunology

The trinity of COVID-19: immunity, inflammation and intervention

Matthew Zirui Tay et al.

NATURE REVIEWS IMMUNOLOGY (2020)

Review Biochemistry & Molecular Biology

Decoding the enigma of antiviral crisis: Does one target molecule regulate all?

Abdullah Mahmud-Al-Rafat et al.

CYTOKINE (2019)

Article Critical Care Medicine

Experimental Rhinovirus Infection as a Human Model of Chronic Obstructive Pulmonary Disease Exacerbation

Patrick Mallia et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)

Article Biochemical Research Methods

WGCNA: an R package for weighted correlation network analysis

Peter Langfelder et al.

BMC BIOINFORMATICS (2008)

Article Multidisciplinary Sciences

Modulation of TNF-α-converting enzyme by the spike protein of SARS-CoV and ACE2 induces TNF-α production and facilitates viral entry

Shiori Haga et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Biochemistry & Molecular Biology

A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury

K Kuba et al.

NATURE MEDICINE (2005)