4.7 Article

One-step modification to identify dual-inhibitors targeting both pancreatic triglyceride lipase and Niemann-Pick C1-like 1

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

Cryo-EM structures of NPC1L1 reveal mechanisms of cholesterol transport and ezetimibe inhibition

Ching-Shin Huang et al.

SCIENCE ADVANCES (2020)

Review Neurosciences

Recent Updates on Obesity Treatments: Available Drugs and Future Directions

Nathalia R. V. Dragano et al.

NEUROSCIENCE (2020)

Article Plant Sciences

Expedient Synthesis of Alphitolic Acid and Its Naturally Occurring 2-O-Ester Derivatives

Somin Park et al.

JOURNAL OF NATURAL PRODUCTS (2019)

Article Chemistry, Multidisciplinary

Intracellular Delivery of Native Proteins Facilitated by Cell-Penetrating Poly(disulfide)s

Linghui Qian et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Article Chemistry, Medicinal

Potential pancreatic lipase inhibitory activity of phenolic constituents from the root bark of Morus alba L.

Manh Tuan Ha et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2016)

Article Pharmacology & Pharmacy

Orlistat limits cholesterol intestinal absorption by Niemann-pick C1-like 1 (NPC1L1) inhibition

Saeed Alqahtani et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2015)

Article Chemistry, Multidisciplinary

Elucidating the Biosynthetic Pathway for Vibralactone: A Pancreatic Lipase Inhibitor with a Fused Bicyclic beta-Lactone

Pei-Ji Zhao et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)

Article Pharmacology & Pharmacy

CETILISTAT FOR THE TREATMENT OF OBESITY

J. Gras

DRUGS OF TODAY (2013)

Article Chemistry, Medicinal

A new pancreatic lipase inhibitor from Broussonetia kanzinoki

Jong Hoon Ahn et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)

Review Physiology

Niemann-Pick C1-Like 1 (NPC1L1) Protein in Intestinal and Hepatic Cholesterol Transport

Lin Jia et al.

ANNUAL REVIEW OF PHYSIOLOGY, VOL 73 (2011)

Article Chemistry, Medicinal

Tetrahydrolipstatin Analogues as Modulators of Endocannabinoid 2-Arachidonoylglycerol Metabolism

Giorgio Ortar et al.

JOURNAL OF MEDICINAL CHEMISTRY (2008)

Review Pharmacology & Pharmacy

Orlistat: A review of its use in the management of obesity

Sheridan Henness et al.

DRUGS (2006)

Article Multidisciplinary Sciences

The target of ezetimibe is Niemann-Pick Cl-Like 1 (NPC1L1)

M Garcia-Calvo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Review Pharmacology & Pharmacy

Ezetimibe - A review of its metabolism, pharmacokinetics and drug interactions

T Kosoglou et al.

CLINICAL PHARMACOKINETICS (2005)

Article Chemistry, Medicinal

Carnosic acid, a new class of lipid absorption inhibitor from sage

K Ninomiya et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2004)

Article Multidisciplinary Sciences

Niemann-Pick C1 like 1 protein is critical for intestinal cholesterol absorption

SW Altmann et al.

SCIENCE (2004)

Article Endocrinology & Metabolism

Effects of orlistat on obesity-related diseases -: a six-month randomized trial

B Guy-Grand et al.

DIABETES OBESITY & METABOLISM (2004)

Review Pharmacology & Pharmacy

Ezetimibe: A selective cholesterol absorption inhibitor

EA Nutescu et al.

PHARMACOTHERAPY (2003)

Review Pharmacology & Pharmacy

Ezetimibe

H Bays

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2002)

Article Endocrinology & Metabolism

Orlistat inhibits dietary cholesterol absorption

B Mittendorfer et al.

OBESITY RESEARCH (2001)