Related references
Note: Only part of the references are listed.Insight on [1,3]thiazolo[4,5-e]isoindoles as tubulin polymerization inhibitors
Virginia Spano et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021)
Design, synthesis and anticancer properties of isocombretapyridines as potent colchicine binding site inhibitors
Wen Shuai et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)
Pyrrolo[2′,3′:3,4]cyclohepta[1,2-d][1,2]oxazoles, a New Class of Antimitotic Agents Active against Multiple Malignant Cell Types
Virginia Spano et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Design, synthesis and biological evaluation of vinyl selenone derivatives as novel microtubule polymerization inhibitors
Huajian Zhu et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)
Colchicine-Binding Site Inhibitors from Chemistry to Clinic: A Review
Eavan C. McLoughlin et al.
PHARMACEUTICALS (2020)
Discovery of novel quinazolines as potential anti-tubulin agents occupying three zones of colchicine domain
Wenlong Li et al.
BIOORGANIC CHEMISTRY (2019)
Design, synthesis and biological evaluation of quinoline-indole derivatives as anti-tubulin agents targeting the colchicine binding site
Wenlong Li et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine binding site
Wenlong Li et al.
BIOORGANIC CHEMISTRY (2019)
Colchicine Binding Site Agent DJ95 Overcomes Drug Resistance and Exhibits Antitumor Efficacy
Kinsie E. Arnst et al.
MOLECULAR PHARMACOLOGY (2019)
Tubulin inhibitors as novel anticancer agents: an overview on patents (2013-2018)
Kashif Haider et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2019)
Nitro-Group-Containing Drugs
Kunal Nepali et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
Discovery of Novel Quinoline-Chalcone Derivatives as Potent Antitumor Agents with Microtubule Polymerization Inhibitory Activity
Wenlong Li et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
Recent advances in trimethoxyphenyl (TMP) based tubulin inhibitors targeting the colchicine binding site
Ling Li et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy
Souvik Banerjee et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Microtubule-Targeting Agents: Strategies To Hijack the Cytoskeleton
Michel O. Steinmetz et al.
TRENDS IN CELL BIOLOGY (2018)
Discovery of novel vinyl sulfone derivatives as anti-tumor agents with microtubule polymerization inhibitory and vascular disrupting activities
Wenlong Li et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
Structural Modification of the 3,4,5-Trimethoxyphenyl Moiety in the Tubulin Inhibitor VERU-111 Leads to Improved Antiproliferative Activities
Qinghui Wang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Discovery of Novel 4-Arylisochromenes as Anticancer Agents Inhibiting Tubulin Polymerization
Wenlong Li et al.
ACS MEDICINAL CHEMISTRY LETTERS (2018)
Tubulin inhibitors targeting the colchicine binding site: a perspective of privileged structures
Wenlong Li et al.
FUTURE MEDICINAL CHEMISTRY (2017)
In Vivo and Mechanistic Studies on Antitumor Lead 7-Methoxy-4-(2-methylquinazolin-4-yl)-3,4-dihydroquinoxalin-2(1H)-one and Its Modification as a Novel Class of Tubulin-Binding Tumor-Vascular Disrupting Agents
Mu-Tian Cui et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Design, Synthesis, and Biological Evaluation of Novel Selenium-Containing Isocombretastatins and Phenstatins as Antitumor Agents
Yanqing Pang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Recent Advances in Heterocyclic Tubulin Inhibitors Targeting the Colchicine Binding Site
Xiaoxin Wu et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2016)
[1,2]Oxazolo[5,4-e]isoindoles as promising tubulin polymerization inhibitors
Virginia Spano et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)
Indole molecules as inhibitors of tubulin polymerization: potential new anticancer agents, an update (2013-2015)
Renukadevi Patil et al.
FUTURE MEDICINAL CHEMISTRY (2016)
Preclinical Activity of New [1,2]Oxazolo[5,4-e]isoindole Derivatives in Diffuse Malignant Peritoneal Mesothelioma
Virginia Spano et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Design, Synthesis, and Biological Evaluation of 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazole Analogues as Potential Anticancer Agents Targeting Tubulin Colchicine Binding Site
Yan-Na Liu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Blocking Blood Flow to Solid Tumors by Destabilizing Tubulin: An Approach to Targeting Tumor Growth
Maria Jesus Perez-Perez et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
A Novel Nitrobenzoate Microtubule Inhibitor that Overcomes Multidrug Resistance Exhibits Antitumor Activity
Yan-Bo Zheng et al.
SCIENTIFIC REPORTS (2016)
Effects of the Tumor-Vasculature-Disrupting Agent Verubulin and Two Heteroaryl Analogues on Cancer Cells, Endothelial Cells, and Blood Vessels
Katharina Mahal et al.
CHEMMEDCHEM (2014)
Optimization of 4-(N-Cycloamino)phenylquinazolines as a Novel Class of Tubulin-Polymerization Inhibitors Targeting the Colchicine Site
Xiao-Feng Wang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Many players in BCL-2 family affairs
Tudor Moldoveanu et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
Targeting caspases in cancer therapeutics
Patrick Hensley et al.
BIOLOGICAL CHEMISTRY (2013)
P-glycoprotein Inhibition as a Therapeutic Approach for Overcoming Multidrug Resistance in Cancer: Current Status and Future Perspectives
Ziyad Binkhathlan et al.
CURRENT CANCER DRUG TARGETS (2013)
Prodrug Study of Plinabulin Using a Click Strategy Focused on the Effects of a Replaceable Water-Solubilizing Moiety
Fumika Yakushiji et al.
CHEMICAL & PHARMACEUTICAL BULLETIN (2012)
The Tubulin Colchicine Domain: a Molecular Modeling Perspective
Alberto Massarotti et al.
CHEMMEDCHEM (2012)
A novel anti-tumor agent, Ln(III) 2-thioacetate benzothiazole induces anti-angiogenic effect and cell death in cancer cell lines
Belal H. M. Hussein et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2012)
Indole molecules as inhibitors of tubulin polymerization: potential new anticancer agents
Shivaputra A. Patil et al.
FUTURE MEDICINAL CHEMISTRY (2012)
Synthesis and Structure-Activity Relationship Study of Antimicrotubule Agents Phenylahistin Derivatives with a Didehydropiperazine-2,5-dione Structure
Yuri Yamazaki et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Design, Synthesis, and Preclinical Evaluations of Novel 4-Substituted 1,5-Diarylanilines as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) Drug Candidates
Lian-Qi Sun et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
The unique characteristics of tumor vasculature and preclinical evidence for its selective disruption by Tumor-Vascular Disrupting Agents
Dietmar W. Siemann
CANCER TREATMENT REVIEWS (2011)
Drugs That Target Dynamic Microtubules: A New Molecular Perspective
Richard A. Stanton et al.
MEDICINAL RESEARCH REVIEWS (2011)
Cardiovascular Toxicity Profiles of Vascular-Disrupting Agents
Ishwaria M. Subbiah et al.
ONCOLOGIST (2011)
Class III β-tubulin expression and in vitro resistance to microtubule targeting agents
C. Stengel et al.
BRITISH JOURNAL OF CANCER (2010)
From signaling pathways to microtubule dynamics: the key players
Sandrine Etienne-Manneville
CURRENT OPINION IN CELL BIOLOGY (2010)
Oxetanes in Drug Discovery: Structural and Synthetic Insights
Georg Wuitschik et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Discovery of Novel 2-Aryl-4-benzoyl-imidazoles Targeting the Colchicines Binding Site in Tubulin As Potential Anticancer Agents
Jianjun Chen et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Microtubule-binding agents: a dynamic field of cancer therapeutics
Charles Dumontet et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Microtubule-Binding Natural Products for Cancer Therapy
Qing-Xi Yue et al.
PLANTA MEDICA (2010)
Transcription-independent p53 apoptosis: an alternative route to death
Daniel Speidel
TRENDS IN CELL BIOLOGY (2010)
Antivascular Actions of Microtubule-Binding Drugs
Edward L. Schwartz
CLINICAL CANCER RESEARCH (2009)
Discovery of N-(4-Methoxyphenyl)-N,2-dimethylquinazolin-4-amine, a Potent Apoptosis Inducer and Efficacious Anticancer Agent with High Blood Brain Barrier Penetration
Nilantha Sirisoma et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Variations in the colchicine-binding domain provide insight into the structural switch of tubulin
Audrey Dorleans et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Targeted anti-mitotic therapies: can we improve on tubulin agents?
Jeffrey R. Jackson et al.
NATURE REVIEWS CANCER (2007)
Microtubules as a target for anticancer drugs
MA Jordan et al.
NATURE REVIEWS CANCER (2004)
Dynamics and mechanics of the microtubule plus end
J Howard et al.
NATURE (2003)