4.7 Article

CAP rigidification of MS-275 and chidamide leads to enhanced antiproliferative effects mediated through HDAC1, 2 and tubulin polymerization inhibition

Related references

Note: Only part of the references are listed.
Article Chemistry, Medicinal

N-alkyl-hydroxybenzoyl anilide hydroxamates as dual inhibitors of HDAC and HSP90, downregulating IFN-gamma induced PD-L1 expression

Samir Mehndiratta et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)

Article Chemistry, Medicinal

Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment

Navdeep Kaur et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)

Article Chemistry, Multidisciplinary

Potent Dual BET/HDAC Inhibitors for Efficient Treatment of Pancreatic Cancer

Shipeng He et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Article Chemistry, Medicinal

Isoindoline scaffold-based dual inhibitors of HDAC6 and HSP90 suppressing the growth of lung cancer in vitro and in vivo

Ritu Ojha et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)

Article Chemistry, Medicinal

Design, synthesis, and biological evaluation of dual targeting inhibitors of histone deacetylase 6/8 and bromodomain BRPF1

Ehab Ghazy et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)

Article Chemistry, Medicinal

Purine/purine isoster based scaffolds as new derivatives of benzamide class of HDAC inhibitors

Kunal Nepali et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)

Article Cell Biology

Discovery of a Novel Hybrid of Vorinostat and Riluzole as a Potent Antitumor Agent

Qifu Xu et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)

Review Biology

Role of tubulin acetylation in cellular functions and diseases

Yoko Nekooki-Machida et al.

MEDICAL MOLECULAR MORPHOLOGY (2020)

Article Chemistry, Medicinal

Discovery of Novel c-Mesenchymal-Epithelia transition factor and histone deacetylase dual inhibitors

Hao Hu et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)

Article Biochemistry & Molecular Biology

Development of a Bestatin-SAHA Hybrid with Dual Inhibitory Activity against APN and HDAC

Jiangying Cao et al.

MOLECULES (2020)

Article Chemistry, Medicinal

Design, synthesis and biological evaluation of a new series of thiazolyl-pyrazolines as dual EGFR and HER2 inhibitors

Belgin Sever et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)

Review Oncology

HDAC Inhibitors in Acute Myeloid Leukemia

Edurne San Jose-Eneriz et al.

CANCERS (2019)

Article Chemistry, Medicinal

1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase

Mei-Jung Lai et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)

Article Chemistry, Medicinal

Improved Selective Class I HDAC and Novel Selective HDAC3 Inhibitors: Beyond Hydroxamic Acids and Benzamides

Alberto Bresciani et al.

ACS MEDICINAL CHEMISTRY LETTERS (2019)

Review Chemistry, Multidisciplinary

Next-generation of selective histone deacetylase inhibitors

Feifei Yang et al.

RSC ADVANCES (2019)

Article Chemistry, Medicinal

1-Aroylindoline-hydroxamic acids as anticancer agents, inhibitors of HSP90 and HDAC

Ritu Ojha et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)

Article Chemistry, Medicinal

Design and Synthesis of Tubulin and Histone Deacetylase Inhibitor Based on iso-Combretastatin A-4

Diana Lamaa et al.

JOURNAL OF MEDICINAL CHEMISTRY (2018)

Article Chemistry, Medicinal

Design, synthesis and biological evaluation of quinoline derivatives as HDAC class I inhibitors

Chen Chen et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)

Article Chemistry, Medicinal

Ring-opened tetrahydro-γ-carbolines display cytotoxicity and selectivity with histone deacetylase isoforms

Kunal Nepali et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)

Review Biotechnology & Applied Microbiology

Chidamide in the treatment of peripheral T-cell lymphoma

Thomas S. Chan et al.

ONCOTARGETS AND THERAPY (2017)

Article Chemistry, Medicinal

Development of Allosteric Hydrazide-Containing Class I Histone Deacetylase Inhibitors for Use in Acute Myeloid Leukemia

Jesse J. McClure et al.

JOURNAL OF MEDICINAL CHEMISTRY (2016)

Review Medicine, General & Internal

Development of chidamide for peripheral T-cell lymphoma, the first orphan drug approved in China

Xianping Lu et al.

INTRACTABLE & RARE DISEASES RESEARCH (2016)

Article Oncology

Panobinostat for the Treatment of Multiple Myeloma

Jacob P. Laubach et al.

CLINICAL CANCER RESEARCH (2015)

Review Pharmacology & Pharmacy

Histone deacetylases: structural determinants of inhibitor selectivity

Carmina Micelli et al.

DRUG DISCOVERY TODAY (2015)

Article Chemistry, Medicinal

Design, synthesis and antiproliferative activities of novel benzamides derivatives as HDAC inhibitors

Yanyang Li et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)

Article Oncology

Histone deacetylase inhibitors: an overview of the clinical studies in solid tumors

Marije Slingerland et al.

ANTI-CANCER DRUGS (2014)

Article Chemistry, Medicinal

Indole-3-ethylsulfamoylphenylacrylamides: Potent histone deacetylase inhibitors with anti-inflammatory activity

Samir Mehndiratta et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2014)

Editorial Material Pharmacology & Pharmacy

Entinostat for treatment of solid tumors and hematologic malignancies

Jeffrey Knipstein et al.

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2011)

Article Biotechnology & Applied Microbiology

Impact of UDP-gluconoryltransferase 2B17 genotype on vorinostat metabolism and clinical outcomes in Asian women with breast cancer

Nan-Soon Wong et al.

PHARMACOGENETICS AND GENOMICS (2011)

Review Pharmacology & Pharmacy

Vinorelbine for non-small cell lung cancer

Maria Carmela Piccirillo et al.

EXPERT OPINION ON DRUG SAFETY (2010)

Article Biotechnology & Applied Microbiology

A pharmacogenetic study of vorinostat glucuronidation

Soonmo Peter Kang et al.

PHARMACOGENETICS AND GENOMICS (2010)

Review Oncology

Histone deacetylase inhibitors that target tubulin

Joerg Schemies et al.

CANCER LETTERS (2009)

Review Oncology

HDAC family: What are the cancer relevant targets?

Olaf Witt et al.

CANCER LETTERS (2009)

Review Genetics & Heredity

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

Michael Haberland et al.

NATURE REVIEWS GENETICS (2009)

Article Biochemistry & Molecular Biology

Pimelic Diphenylamide 106 Is a Slow, Tight-binding Inhibitor of Class I Histone Deacetylases

C. James Chou et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Review Cell Biology

The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men

Xiang-Jiao Yang et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)

Review Biochemistry & Molecular Biology

Discovery and development of SAHA as an anticancer agent

P. A. Marks

ONCOGENE (2007)

Review Biochemistry & Molecular Biology

MS-275, a potent orally available inhibitor of histone deacetylases - The development of an anticancer agent

Holger Hess-Stumpp et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2007)

Article Multidisciplinary Sciences

HDAC6 is a microtubule-associated deacetylase

C Hubbert et al.

NATURE (2002)

Review Biotechnology & Applied Microbiology

Histone-deacetylase inhibitors: Novel drugs for the treatment of cancer

RW Johnstone

NATURE REVIEWS DRUG DISCOVERY (2002)

Article Biochemistry & Molecular Biology

The Protein Data Bank

HM Berman et al.

NUCLEIC ACIDS RESEARCH (2000)