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Impaired Rivaroxaban Clearance in Mild Renal Insufficiency With Verapamil Coadministration: Potential Implications for Bleeding Risk and Dose Selection
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Drug-induced thrombocytopenia after anticoagulation with rivaroxaban
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Annie M. Young et al.
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Regional Gastrointestinal Absorption of Apixaban in Healthy Subjects
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Correlation of non-vitamin K antagonist oral anticoagulant exposure and cerebral microbleeds in Chinese patients with atrial fibrillation
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LANCET NEUROLOGY (2018)
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LANCET NEUROLOGY (2018)
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STROKE (2018)
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STROKE (2018)
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NEUROLOGY-CLINICAL PRACTICE (2018)
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BLOOD ADVANCES (2018)
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CLINICAL PHARMACOKINETICS (2018)
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EUROPACE (2017)
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EUROPACE (2017)
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HEART (2017)
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Chan Soon Park et al.
HEART RHYTHM (2017)
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Direct oral anticoagulants in patients with hypertrophic cardiomyopathy and atrial fibrillation
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Apixaban in Patients With Atrial Fibrillation After Transfemoral Aortic Valve Replacement
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JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2017)
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2017 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants
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The Changing Landscape for Stroke Prevention in AF Findings From the GLORIA-AF Registry Phase 2
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Apixaban Pharmacokinetics at Steady State in Hemodialysis Patients
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JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2017)
Reversal of apixaban anticoagulation by four-factor prothrombin complex concentrates in healthy subjects: a randomized three-period crossover study
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Effect of major gastrointestinal tract surgery on the absorption and efficacy of direct acting oral anticoagulants (DOACs)
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NEW ENGLAND JOURNAL OF MEDICINE (2017)
Dual Antithrombotic Therapy with Dabigatran after PCI in Atrial Fibrillation
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Idarucizumab for Dabigatran Reversal - Full Cohort Analysis
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Rivaroxaban or Aspirin for Extended Treatment of Venous Thromboembolism
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Uninterrupted Dabigatran versus Warfarin for Ablation in Atrial Fibrillation
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Falls, non-accidental falls and syncope in community-dwelling adults aged 50 years and older: Implications for cardiovascular assessment
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PLOS ONE (2017)
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STROKE (2017)
Thromboembolic and bleeding complications during oral anticoagulation therapy in cancer patients with atrial fibrillation: a Danish nationwide population-based cohort study
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JOURNAL OF STROKE (2017)
Laboratory Monitoring of Non-Vitamin K Antagonist Oral Anticoagulant Use in Patients With Atrial Fibrillation A Review
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JAMA CARDIOLOGY (2017)
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Edoxaban for the management of elderly Japanese patients with atrial fibrillation ineligible for standard oral anticoagulant therapies: Rationale and design of the ELDERCARE-AF study
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Differential Influence of the Antiretroviral Pharmacokinetic Enhancers Ritonavir and Cobicistat on Intestinal P-Glycoprotein Transport and the Pharmacokinetic/Pharmacodynamic Disposition of Dabigatran
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DRUGS & AGING (2017)
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BLOOD (2017)
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BLOOD (2017)
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Thrombocytopenia induced by dabigatran: two case reports
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BMC NEUROLOGY (2017)
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CHEST (2017)
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BLOOD REVIEWS (2017)
Management of Severe Bleeding in Patients Treated with Direct Oral Anticoagulants An Observational Registry Analysis
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ANESTHESIOLOGY (2017)
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AMERICAN JOURNAL OF MEDICINE (2017)
Intracranial hemorrhage in patients with atrial fibrillation receiving anticoagulation therapy
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CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2017)
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AMERICAN JOURNAL OF MEDICINE (2017)
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CIRCULATION RESEARCH (2017)
Non-vitamin K antagonist oral anticoagulants in atrial fibrillation accompanying mitral stenosis: the concept for a trial
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EUROPACE (2016)
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Nonvitamin K Anticoagulant Agents in Patients With Advanced Chronic Kidney Disease or on Dialysis With AF
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Off-Label Dosing of Non-Vitamin K Antagonist Oral Anticoagulants and Adverse Outcomes The ORBIT-AF II Registry
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Obesity and risk of bleeding: the SMART study.
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To measure or not to measure direct oral anticoagulants before surgery or invasive procedures: reply
A. Tripodi
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Use of the direct oral anticoagulants in obese patients: guidance from the SSC of the ISTH
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Guidance for the practical management of the direct oral anticoagulants (DOACs) in VTE treatment
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James M. Feeney et al.
JOURNAL OF TRAUMA AND ACUTE CARE SURGERY (2016)
Occurrence of death and stroke in patients in 47 countries 1 year after presenting with atrial fibrillation: a cohort study
Jeff S. Healey et al.
LANCET (2016)
Rate Control versus Rhythm Control for Atrial Fibrillation after Cardiac Surgery
A. M. Gillinov et al.
NEW ENGLAND JOURNAL OF MEDICINE (2016)
Prevention of Bleeding in Patients with Atrial Fibrillation Undergoing PCI
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NEW ENGLAND JOURNAL OF MEDICINE (2016)
Andexanet Alfa for Acute Major Bleeding Associated with Factor Xa Inhibitors
Stuart J. Connolly et al.
NEW ENGLAND JOURNAL OF MEDICINE (2016)
Reduced Anticoagulant Effect of Dabigatran in a Patient Receiving Concomitant Phenytoin
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PHARMACOTHERAPY (2016)
Validation of a Modified CHA2DS2-VASc Score for Stroke Risk Stratification in Asian Patients With Atrial Fibrillation: A Nationwide Cohort Study
Tze-Fan Chao et al.
STROKE (2016)
Atrial Fibrillation Patients Treated With Long-Term Warfarin Anticoagulation Have Higher Rates of All Dementia Types Compared With Patients Receiving Long-Term Warfarin for Other Indications
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JOURNAL OF THE AMERICAN HEART ASSOCIATION (2016)
Compared to warfarin, direct oral anticoagulants are associated with lower mortality in patients with blunt traumatic intracranial hemorrhage: A TQIP study
James M. Feeney et al.
JOURNAL OF TRAUMA AND ACUTE CARE SURGERY (2016)
Stroke, Bleeding, and Mortality Risks in Elderly Medicare Beneficiaries Treated With Dabigatran or Rivaroxaban for Nonvalvular Atrial Fibrillation
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JAMA INTERNAL MEDICINE (2016)
Extended duration of anticoagulation with edoxaban in patients with venous thromboembolism: a post-hoc analysis of the Hokusai-VTE study
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LANCET HAEMATOLOGY (2016)
Apixaban 5 mg Twice Daily and Clinical Outcomes in Patients With Atrial Fibrillation and Advanced Age, Low Body Weight, or High Creatinine
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JAMA CARDIOLOGY (2016)
Racial Differences in Atrial Fibrillation-Related Cardiovascular Disease and Mortality The Atherosclerosis Risk in Communities (ARIC) Study
Jared W. Magnani et al.
JAMA CARDIOLOGY (2016)
Impact of the Direct Oral Anticoagulants on Activated Clotting Time
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The Influence of Socioeconomic Status on Selection of Anticoagulation for Atrial Fibrillation
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PLOS ONE (2016)
Comparison of Safety of Left Atrial Catheter Ablation Procedures for Atrial Arrhythmias Under Continuous Anticoagulation With Apixaban Versus Phenprocoumon
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AMERICAN JOURNAL OF CARDIOLOGY (2015)
Dose-Finding Study of Rivaroxaban in Hemodialysis Patients
An S. De Vriese et al.
AMERICAN JOURNAL OF KIDNEY DISEASES (2015)
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Alvaro Avezum et al.
CIRCULATION (2015)
Dabigatran and Rivaroxaban Use in Atrial Fibrillation Patients on Hemodialysis
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CIRCULATION (2015)
Short-Term Safety and Plasma Concentrations of Edoxaban in Japanese Patients With Non-Valvular Atrial Fibrillation and Severe Renal Impairment
Yukihiro Koretsune et al.
CIRCULATION JOURNAL (2015)
The Effect of Rifampin on the Pharmacokinetics of Edoxaban in Healthy Adults
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CLINICAL DRUG INVESTIGATION (2015)
Antithrombotic management in patients undergoing electrophysiological procedures: a European Heart Rhythm Association (EHRA) position document endorsed by the ESCWorking Group Thrombosis, Heart Rhythm Society (HRS), and Asia Pacific Heart Rhythm Society (APHRS)
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EUROPACE (2015)
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Hein Heidbuchel et al.
EUROPACE (2015)
Edoxaban vs. warfarin in patients with atrial fibrillation on amiodarone: a subgroup analysis of the ENGAGE AF-TIMI 48 trial
J. Steffel et al.
EUROPEAN HEART JOURNAL (2015)
Uninterrupted rivaroxaban vs. uninterrupted vitamin K antagonists for catheter ablation in non-valvular atrial fibrillation
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EUROPEAN HEART JOURNAL (2015)
Prevention of Dabigatran-Related Gastrointestinal Bleeding With Gastroprotective Agents: A Population-Based Study
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GASTROENTEROLOGY (2015)
Feasibility and safety of uninterrupted periprocedural apixaban administration in patients undergoing radiofrequency catheter ablation for atrial fibrillation: Results from a multicenter study
Luigi Di Biase et al.
HEART RHYTHM (2015)
Uninterrupted dabigatran versus warfarin in the treatment of intracardiac thrombus in patients with non-valvular atrial fibrillation
Li Hao et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2015)
Evaluation of regional gastrointestinal absorption of edoxaban using the enterion capsule
Dolly A. Parasrampuria et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2015)
Choosing the right drug to fit the patient when selecting oral anticoagulation for stroke prevention in atrial fibrillation
A. M. Shields et al.
JOURNAL OF INTERNAL MEDICINE (2015)
Age Threshold for Increased Stroke Risk Among Patients With Atrial Fibrillation A Nationwide Cohort Study From Taiwan
Tze-Fan Chao et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2015)
Recommendation on the nomenclature for oral anticoagulants: communication from the SSC of the ISTH
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JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2015)
Association between edoxaban dose, concentration, anti-Factor Xa activity, and outcomes: an analysis of data from the randomised, double-blind ENGAGE AF-TIMI 48 trial
Christian T. Ruff et al.
LANCET (2015)
Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation
James D. Douketis et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Polymer-free Drug-Coated Coronary Stents in Patients at High Bleeding Risk
Philip Urban et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction
Marc P. Bonaca et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Gastrointestinal bleeding in patients receiving oral anticoagulation: Current treatment and pharmacological perspectives
Alessandro Di Minno et al.
THROMBOSIS RESEARCH (2015)
The pooled incidence of post-stroke seizure in 102 008 patients
Safeng Zou et al.
TOPICS IN STROKE REHABILITATION (2015)
Should dual antiplatelet therapy be used in patients following coronary artery bypass surgery? A meta-analysis of randomized controlled trials
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BMC SURGERY (2015)
Monitoring and reversal of direct oral anticoagulants
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HEMATOLOGY-AMERICAN SOCIETY OF HEMATOLOGY EDUCATION PROGRAM (2015)
Balancing stroke and bleeding risks in patients with atrial fibrillation and renal failure: the Swedish Atrial Fibrillation Cohort study
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EUROPEAN HEART JOURNAL (2015)
Cardiovascular, Bleeding, and Mortality Risks in Elderly Medicare Patients Treated With Dabigatran or Warfarin for Nonvalvular Atrial Fibrillation
David J. Graham et al.
CIRCULATION (2015)
Edoxaban Effects on Bleeding Following Punch Biopsy and Reversal by a 4-Factor Prothrombin Complex Concentrate
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CIRCULATION (2015)
Vitamin K Antagonists Predispose to Calciphylaxis in Patients width End-Stage Renal Disease
Peter A. G. Galloway et al.
NEPHRON (2015)
Efficacy and safety of edoxaban versus enoxaparin for the prevention of venous thromboembolism following total hip arthroplasty: STARS J-V
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THROMBOSIS JOURNAL (2015)
Efficacy and Safety of Apixaban Compared with Warfarin for Stroke Prevention in Patients with Atrial Fibrillation from East Asia: A Subanalysis of the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial
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AMERICAN HEART JOURNAL (2014)
Management and clinical outcomes in patients treated with apixaban vs warfarin undergoing procedures
David Garcia et al.
BLOOD (2014)
Rates, management, and outcome of rivaroxaban bleeding in daily care: results from the Dresden NOAC registry
Jan Beyer-Westendorf et al.
BLOOD (2014)
Evaluation of the effect of naproxen on the pharmacokinetics and pharmacodynamics of apixaban
Charles Frost et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2014)
Warfarin Use and the Risk for Stroke and Bleeding in Patients With Atrial Fibrillation Undergoing Dialysis
Mitesh Shah et al.
CIRCULATION (2014)
Periprocedural Stroke and Bleeding Complications in Patients Undergoing Catheter Ablation of Atrial Fibrillation With Different Anticoagulation Management Results From the Role of Coumadin in Preventing Thromboembolism in Atrial Fibrillation (AF) Patients Undergoing Catheter Ablation (COMPARE) Randomized Trial
Luigi Di Biase et al.
CIRCULATION (2014)
Efficacy and Safety of Rivaroxaban Compared With Warfarin Among Elderly Patients With Nonvalvular Atrial Fibrillation in the Rivaroxaban Once Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF)
Jonathan L. Halperin et al.
CIRCULATION (2014)
Outcomes of Temporary Interruption of Rivaroxaban Compared With Warfarin in Patients With Nonvalvular Atrial Fibrillation
Matthew W. Sherwood et al.
CIRCULATION (2014)
Clinical Pharmacokinetic and Pharmacodynamic Profile of Rivaroxaban
Wolfgang Mueck et al.
CLINICAL PHARMACOKINETICS (2014)
Dementia and Cognitive Impairment Epidemiology, Diagnosis, and Treatment
Julie Hugo et al.
CLINICS IN GERIATRIC MEDICINE (2014)
Efficacy and safety of apixaban compared with warfarin according to age for stroke prevention in atrial fibrillation: observations from the ARISTOTLE trial
Sigrun Halvorsen et al.
EUROPEAN HEART JOURNAL (2014)
Management of major bleeding events in patients treated with rivaroxaban vs. warfarin: results from the ROCKET AF trial
Jonathan P. Piccini et al.
EUROPEAN HEART JOURNAL (2014)
Clinical characteristics and outcomes with rivaroxaban vs. warfarin in patients with non-valvular atrial fibrillation but underlying native mitral and aortic valve disease participating in the ROCKET AF trial
Gunter Breithardt et al.
EUROPEAN HEART JOURNAL (2014)
Peri-interventional management of novel oral anticoagulants in daily care: results from the prospective Dresden NOAC registry
Jan Beyer-Westendorf et al.
EUROPEAN HEART JOURNAL (2014)
Prolonged anticoagulant activity of rivaroxaban in a polymorbid elderly female with non-convulsive epileptic state
Claudia Stoellberger et al.
HEART & LUNG (2014)
Acute Thrombocytopenia after Initiating Anticoagulation with Rivaroxaban
Yohei Mima et al.
INTERNAL MEDICINE (2014)
Direct Oral Anticoagulants New Drugs and New Concepts
Jerrold H. Levy et al.
JACC-CARDIOVASCULAR INTERVENTIONS (2014)
Population Pharmacokinetics and Pharmacodynamics of Rivaroxaban in Patients with Non-valvular Atrial Fibrillation: Results from ROCKET AF
I. G. Girgis et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2014)
The Effect of Dabigatran Plasma Concentrations and Patient Characteristics on the Frequency of Ischemic Stroke and Major Bleeding in Atrial Fibrillation Patients The RE-LY Trial (Randomized Evaluation of Long-Term Anticoagulation Therapy)
Paul A. Reilly et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2014)
Net Clinical Benefit of Antithrombotic Therapy in Patients With Atrial Fibrillation and Chronic Kidney Disease A Nationwide Observational Cohort Study
Anders Nissen Bonde et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2014)
Laboratory Measurement of the Anticoagulant Activity of the Non-Vitamin K Oral Anticoagulants
Adam Cuker et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2014)
Major Bleeding in Patients With Atrial Fibrillation Receiving Apixaban or Warfarin
Elaine M. Hylek et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2014)
Rivaroxaban presents a better pharmacokinetic profile than dabigatran in an obese non-diabetic stroke patient
Apostolos Safouris et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2014)
Comparison of three-factor and four-factor prothrombin complex concentrates regarding reversal of the anticoagulant effects of rivaroxaban in healthy volunteers
M. Levi et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2014)
Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials
Christian T. Ruff et al.
LANCET (2014)
Aspirin in Patients Undergoing Noncardiac Surgery
P. J. Devereaux et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Twelve or 30 Months of Dual Antiplatelet Therapy after Drug-Eluting Stents
Laura Mauri et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
New Oral Anticoagulants and the Cancer Patient
Nicholas J. Short et al.
ONCOLOGIST (2014)
Warfarin Dosing Changes After Bariatric Surgery: Implications on the Mechanism for Altered Dose Requirements and Safety Concerns-An Alternative Viewpoint
Lingtak-Neander Chan
PHARMACOTHERAPY (2014)
Rivaroxaban for Stroke Prevention in East Asian Patients From the ROCKET AF Trial
Ka Sing Lawrence Wong et al.
STROKE (2014)
Vitamin K Antagonists and Risk of Subdural Hematoma Meta-Analysis of Randomized Clinical Trials
Ben J. Connolly et al.
STROKE (2014)
Cerebrovascular Events in 21 105 Patients With Atrial Fibrillation Randomized to Edoxaban Versus Warfarin Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48
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STROKE (2014)
Intracranial Hemorrhage Among Patients With Atrial Fibrillation Anticoagulated With Warfarin or Rivaroxaban The Rivaroxaban Once Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation
Graeme J. Hankey et al.
STROKE (2014)
Point-of-Care Coagulation Testing for Assessment of the Pharmacodynamic Anticoagulant Effect of Direct Oral Anticoagulant
Helen Mani et al.
THERAPEUTIC DRUG MONITORING (2014)
Patient outcomes using the European label for dabigatran A post-hoc analysis from the RE-LY database
Gregory Y. H. Lip et al.
THROMBOSIS AND HAEMOSTASIS (2014)
Safety and Efficacy of Edoxaban, an Oral Factor Xa Inhibitor, Versus Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty: The STARS E-3 Trial
Takeshi Fuji et al.
THROMBOSIS RESEARCH (2014)
Rivaroxaban Crushed Tablet Suspension Characteristics and Relative Bioavailability in Healthy Adults When Administered Orally or Via Nasogastric Tube
Kenneth T. Moore et al.
CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT (2014)
Warfarin dosing after bariatric surgery: a retrospective study of 10 patients previously stable on chronic warfarin therapy
A. M. Schullo-Feulner et al.
CLINICAL OBESITY (2014)
Simple and rapid assay for effect of the new oral anticoagulant (NOAC) rivaroxaban: preliminary results support further tests with all NOACs
Raul Altman et al.
THROMBOSIS JOURNAL (2014)
Drug-Drug Interaction Studies of Cardiovascular Drugs Involving P-Glycoprotein, an Efflux Transporter, on the Pharmacokinetics of Edoxaban, an Oral Factor Xa Inhibitor
Jeanne Mendell et al.
AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS (2013)
Expert consensus of the French Society of Geriatrics and Gerontology and the French Society of Cardiology on the management of atrial fibrillation in elderly people
Olivier Hanon et al.
ARCHIVES OF CARDIOVASCULAR DISEASES (2013)
Effect of extremes of body weight on the pharmacokinetics, pharmacodynamics, safety and tolerability of apixaban in healthy subjects
Vijay V. Upreti et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2013)
Safety, pharmacokinetics and pharmacodynamics of multiple oral doses of apixaban, a factor Xa inhibitor, in healthy subjects
Charles Frost et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2013)
Co-administration of rivaroxaban with drugs that share its elimination pathways: pharmacokinetic effects in healthy subjects
Wolfgang Mueck et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2013)
Factors Affecting Quality of Anticoagulation Control Among Patients With Atrial Fibrillation on Warfarin The SAMe-TT2R2 Score
Stavros Apostolakis et al.
CHEST (2013)
Concomitant Use of Antiplatelet Therapy with Dabigatran or Warfarin in the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) Trial
Antonio L. Dans et al.
CIRCULATION (2013)
Management and Outcomes of Major Bleeding During Treatment With Dabigatran or Warfarin
Ammar Majeed et al.
CIRCULATION (2013)
Use of Dabigatran for Periprocedural Anticoagulation in Patients Undergoing Catheter Ablation for Atrial Fibrillation
Mohamed Bassiouny et al.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY (2013)
Efficacy and Safety of Rivaroxaban in Patients With Heart Failure and Nonvalvular Atrial Fibrillation Insights From ROCKET AF
Sean van Diepen et al.
CIRCULATION-HEART FAILURE (2013)
Left Ventricular Systolic Dysfunction, Heart Failure, and the Risk of Stroke and Systemic Embolism in Patients With Atrial Fibrillation Insights From the ARISTOTLE Trial
John J. V. McMurray et al.
CIRCULATION-HEART FAILURE (2013)
Apixaban as an Alternate Oral Anticoagulant for the Management of Patients With Heparin-Induced Thrombocytopenia
Jeanine M. Walenga et al.
CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS (2013)
European Heart Rhythm Association Practical Guide on the use of new oral anticoagulants in patients with non-valvular atrial fibrillation
Hein Heidbuchel et al.
EUROPACE (2013)
Obesity results in progressive atrial structural and electrical remodeling: Implications for atrial fibrillation
Hany S. Abed et al.
HEART RHYTHM (2013)
Incident thromboembolism and heart failure associated with new-onset atrial fibrillation in cancer patients
Yu-feng Hu et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2013)
Effect of Weight Reduction and Cardiometabolic Risk Factor Management on Symptom Burden and Severity in Patients With Atrial Fibrillation A Randomized Clinical Trial
Hany S. Abed et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2013)
Dual Anti-platelet Therapy After Coronary Artery Bypass Grafting: Is There Any Benefit? A Systematic Review and Meta-Analysis
Salil V. Deo et al.
JOURNAL OF CARDIAC SURGERY (2013)
The Effects of the Antiplatelet Agents, Aspirin and Naproxen, on Pharmacokinetics and Pharmacodynamics of the Anticoagulant Edoxaban, a Direct Factor Xa Inhibitor
Jeanne Mendell et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2013)
Measuring oral direct inhibitors of thrombin and factor Xa: a recommendation from the Subcommittee on Control of Anticoagulation of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis
T. Baglin et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2013)
Comparison of initial warfarin response in obese patients versus non-obese patients
Jessica L. Wallace et al.
JOURNAL OF THROMBOSIS AND THROMBOLYSIS (2013)
Ischemic Stroke in an Obese Patient Receiving Dabigatran
Lorenz Breuer et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Dabigatran versus Warfarin in Patients with Mechanical Heart Valves
John W. Eikelboom et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Apixaban for Extended Treatment of Venous Thromboembolism
Giancarlo Agnelli et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Edoxaban versus Warfarin for the Treatment of Symptomatic Venous Thromboembolism
Harry R. Bueller et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Edoxaban versus Warfarin in Patients with Atrial Fibrillation
Robert P. Giugliano et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Extended Use of Dabigatran, Warfarin, or Placebo in Venous Thromboembolism
Sam Schulman et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Oral Apixaban for the Treatment of Acute Venous Thromboembolism
Giancarlo Agnelli et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Warfarin Users Prone to Coagulopathy in First 30 Days After Hospital Discharge from Gastric Bypass
Peter Bechtel et al.
OBESITY SURGERY (2013)
A Review of Potential Harmful Interactions between Anticoagulant/Antiplatelet Agents and Chinese Herbal Medicines
Hsin-Hui Tsai et al.
PLOS ONE (2013)
Preventing Stroke in Patients With Chronic Kidney Disease and Atrial Fibrillation Benefit and Risks of Old and New Oral Anticoagulants
Holger Reinecke et al.
STROKE (2013)
Dabigatran Versus Warfarin Effects on Ischemic and Hemorrhagic Strokes and Bleeding in Asians and Non-Asians With Atrial Fibrillation
Masatsugu Hori et al.
STROKE (2013)
Impact of apixaban on routine and specific coagulation assays: a practical laboratory guide
Jonathan Douxfils et al.
THROMBOSIS AND HAEMOSTASIS (2013)
Racial Differences in the Prevalence and Outcomes of Atrial Fibrillation Among Patients Hospitalized With Heart Failure
Kevin L. Thomas et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2013)
The transport of antiepileptic drugs by P-glycoprotein
Chunbo Zhang et al.
ADVANCED DRUG DELIVERY REVIEWS (2012)
Interpretation of Point-of-care INR Results in Patients Treated with Dabigatran
Joanne van Ryn et al.
AMERICAN JOURNAL OF MEDICINE (2012)
Evaluation of Prothrombin Complex Concentrate and Recombinant Activated Factor VII to Reverse Rivaroxaban in a Rabbit Model
Anne Godier et al.
ANESTHESIOLOGY (2012)
Heparin-induced thrombocytopenia: in vitro studies on the interaction of dabigatran, rivaroxaban, and low-sulfated heparin, with platelet factor 4 and anti-PF4/heparin antibodies
Krystin Krauel et al.
BLOOD (2012)
Recombinant factor VIIa (rFVIIa) and hemodialysis to manage massive dabigatran-associated postcardiac surgery bleeding
Theodore E. Warkentin et al.
BLOOD (2012)
Periprocedural Bleeding and Thromboembolic Events With Dabigatran Compared With Warfarin Results From the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) Randomized Trial
Jeff S. Healey et al.
CIRCULATION (2012)
Variation in Warfarin Dose Adjustment Practice Is Responsible for Differences in the Quality of Anticoagulation Control Between Centers and Countries An Analysis of Patients Receiving Warfarin in the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) Trial
Harriette G. C. Van Spall et al.
CIRCULATION (2012)
Rivaroxaban vs. Warfarin in Japanese Patients With Atrial Fibrillation - The J-ROCKET AF Study
Masatsugu Hori et al.
CIRCULATION JOURNAL (2012)
A clinical decision aid for the selection of antithrombotic therapy for the prevention of stroke due to atrial fibrillation
Stephen Andrew LaHaye et al.
EUROPEAN HEART JOURNAL (2012)
Apixaban in renal insufficiency: successful navigation between the Scylla and Charybdis
Jan Steffel et al.
EUROPEAN HEART JOURNAL (2012)
Efficacy of apixaban when compared with warfarin in relation to renal function in patients with atrial fibrillation: insights from the ARISTOTLE trial
Stefan H. Hohnloser et al.
EUROPEAN HEART JOURNAL (2012)
Absence of Clinically Relevant Interactions between Rivaroxaban - an Oral, Direct Factor Xa Inhibitor - and Digoxin or Atorvastatin in Healthy Subjects
D. Kubitza et al.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH (2012)
Reversal of dabigatran anticoagulation by prothrombin complex concentrate (Beriplex P/N) in a rabbit model
I. Pragst et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2012)
Rivaroxaban in Patients with a Recent Acute Coronary Syndrome
Jessica L. Mega et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Stroke and Bleeding in Atrial Fibrillation with Chronic Kidney Disease
Jonas Bjerring Olesen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Oral Rivaroxaban for the Treatment of Symptomatic Pulmonary Embolism
Harry R. Buller et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Left Atrial Catheter Ablation and Ischemic Stroke
Karl Georg Haeusler et al.
STROKE (2012)
Poor Prognosis in Warfarin-Associated Intracranial Hemorrhage Despite Anticoagulation Reversal
Dar Dowlatshahi et al.
STROKE (2012)
Impact of dabigatran on a large panel of routine or specific coagulation assays Laboratory recommendations for monitoring of dabigatran etexilate
Jonathan Douxfils et al.
THROMBOSIS AND HAEMOSTASIS (2012)
Dabigatran etexilate for stroke prevention in patients with atrial fibrillation: Resolving uncertainties in routine practice
Menno V. Huisman et al.
THROMBOSIS AND HAEMOSTASIS (2012)
Modelling and simulation of edoxaban exposure and response relationships in patients with atrial fibrillation
Daniel E. Salazar et al.
THROMBOSIS AND HAEMOSTASIS (2012)
Assessment of the impact of rivaroxaban on coagulation assays: Laboratory recommendations for the monitoring of rivaroxaban and review of the literature
Jonathan Douxfils et al.
THROMBOSIS RESEARCH (2012)
Perioperative management of patients who are receiving warfarin therapy: an evidence-based and practical approach
James D. Douketis
BLOOD (2011)
Risk of Bleeding With 2 Doses of Dabigatran Compared With Warfarin in Older and Younger Patients With Atrial Fibrillation An Analysis of the Randomized Evaluation of Long-Term Anticoagulant Therapy (RE-LY) Trial
John W. Eikelboom et al.
CIRCULATION (2011)
Reversal of Rivaroxaban and Dabigatran by Prothrombin Complex Concentrate A Randomized, Placebo-Controlled, Crossover Study in Healthy Subjects
Elise S. Eerenberg et al.
CIRCULATION (2011)
Rivaroxaban Population Pharmacokinetic Analyses in Patients Treated for Acute Deep-Vein Thrombosis and Exposure Simulations in Patients with Atrial Fibrillation Treated for Stroke Prevention
Wolfgang Mueck et al.
CLINICAL PHARMACOKINETICS (2011)
Novel oral anticoagulants: focus on stroke prevention and treatment of venous thrombo-embolism
Jan Steffel et al.
EUROPEAN HEART JOURNAL (2011)
Non-cardiac surgery in patients with coronary stents: the RECO study
Pierre Albaladejo et al.
HEART (2011)
Effect of Multiple Doses of Omeprazole on the Pharmacokinetics, Pharmacodynamics, and Safety of a Single Dose of Rivaroxaban
Kenneth Todd Moore et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2011)
The effect of antiepileptic drugs on coagulation and bleeding in the perioperative period of epilepsy surgery: The Cleveland Clinic experience
Crystal Manohar et al.
JOURNAL OF CLINICAL NEUROSCIENCE (2011)
Effects of Food on the Pharmacokinetics of Edoxaban, an Oral Direct Factor Xa Inhibitor, in Healthy Volunteers
Jeanne Mendell et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2011)
In Vitro and In Vivo P-Glycoprotein Transport Characteristics of Rivaroxaban
Mark Jean Gnoth et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2011)
Population pharmacokinetic analysis of the oral thrombin inhibitor dabigatran etexilate in patients with non-valvular atrial fibrillation from the RE-LY trial
K-H Liesenfeld et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2011)
Incidence and predictors of acute symptomatic seizures after stroke
E. Beghi et al.
NEUROLOGY (2011)
Apixaban in Patients with Atrial Fibrillation
Stuart J. Connolly et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Apixaban versus Warfarin in Patients with Atrial Fibrillation
Christopher B. Granger et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation
Manesh R. Patel et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Exposure to CYP3A4-inducing and CYP3A4-non-inducing antiepileptic agents and the risk of fractures
Hedi Schelleman et al.
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY (2011)
Early treatment after stroke for the prevention of late epileptic seizures: A report on the problems performing a randomised placebo-controlled double-blind trial aimed at anti-epileptogenesis
J. H. van Tuijl et al.
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY (2011)
Hemostatic Therapy in Experimental Intracerebral Hemorrhage Associated With the Direct Thrombin Inhibitor Dabigatran
Wei Zhou et al.
STROKE (2011)
Apixaban versus enoxaparin in patients with total knee arthroplasty A meta-analysis of randomised trials
Jiahao Huang et al.
THROMBOSIS AND HAEMOSTASIS (2011)
Oral dabigatran versus enoxaparin for thromboprophylaxis after primary total hip arthroplasty (RE-NOVATE II) A randomised, double-blind, non-inferiority trial
Bengt I. Eriksson et al.
THROMBOSIS AND HAEMOSTASIS (2011)
Chronic kidney disease and prevalent atrial fibrillation: The Chronic Renal Insufficiency Cohort (CRIC)
Elsayed Z. Soliman et al.
AMERICAN HEART JOURNAL (2010)
Influence of Renal Impairment on the Pharmacokinetics and Pharmacodynamics of Oral Dabigatran Etexilate An Open-Label, Parallel-Group, Single-Centre Study
Joachim Stangier et al.
CLINICAL PHARMACOKINETICS (2010)
In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies
Lifei Wang et al.
DRUG METABOLISM AND DISPOSITION (2010)
Clinical Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Novel Factor Xa Inhibitor Edoxaban in Healthy Volunteers
Koichiro Ogata et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2010)
Definition of major bleeding in clinical investigations of antihemostatic medicinal products in surgical patients
S. Schulman et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2010)
The Development and Validation of a Brief Performance-Based Fall Risk Assessment Tool for Use in Primary Care
Anne Tiedemann et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2010)
Oral Rivaroxaban for Symptomatic Venous Thromboembolism.
Rupert Bauersachs et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Mexican Americans With Atrial Fibrillation Have More Recurrent Strokes Than Do Non-Hispanic Whites
Jennifer R. Simpson et al.
STROKE (2010)
Dabigatran etexilate - a novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity
Joanne van Ryn et al.
THROMBOSIS AND HAEMOSTASIS (2010)
Close bidirectional relationship between chronic kidney disease and atrial fibrillation: The Niigata preventive medicine study
Hiroshi Watanabe et al.
AMERICAN HEART JOURNAL (2009)
Incidence of atrial fibrillation in whites and African-Americans: The Atherosclerosis Risk in Communities (ARIC) study
Alvaro Alonso et al.
AMERICAN HEART JOURNAL (2009)
Coadministration of Dabigatran Etexilate and Atorvastatin Assessment of Potential Impact on Pharmacokinetics and Pharmacodynamics
Joachim Stangier et al.
AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS (2009)
Apixaban, an Oral, Direct, Selective Factor Xa Inhibitor, in Combination With Antiplatelet Therapy After Acute Coronary Syndrome Results of the Apixaban for Prevention of Acute Ischemic and Safety Events (APPRAISE) Trial
John H. Alexander et al.
CIRCULATION (2009)
Impact of Proteinuria and Glomerular Filtration Rate on Risk of Thromboembolism in Atrial Fibrillation The Anticoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study
Alan S. Go et al.
CIRCULATION (2009)
Comparative Pharmacodynamics and Pharmacokinetics of Oral Direct Thrombin and Factor Xa Inhibitors in Development
Bengt I. Eriksson et al.
CLINICAL PHARMACOKINETICS (2009)
Apixaban Metabolism and Pharmacokinetics after Oral Administration to Humans
Nirmala Raghavan et al.
DRUG METABOLISM AND DISPOSITION (2009)
Is a first acute symptomatic seizure epilepsy? Mortality and risk for recurrent seizure
Dale C. Hesdorffer et al.
EPILEPSIA (2009)
Quality of Care for Atrial Fibrillation Among Patients Hospitalized for Heart Failure
Jonathan P. Piccini et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2009)
Dilemmas in the Management of Atrial Fibrillation in Chronic Kidney Disease
Holger Reinecke et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2009)
Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty (RECORD4): a randomised trial
Alexander G. G. Turpie et al.
LANCET (2009)
Dabigatran versus Warfarin in Patients with Atrial Fibrillation.
Stuart J. Connolly et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Dabigatran versus Warfarin in the Treatment of Acute Venous Thromboembolism.
Sam Schulman et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Use of Stroke Secondary Prevention Services Are There Disparities in Care?
Joseph S. Ross et al.
STROKE (2009)
Chronic atrial fibrillation:: Incidence, prevalence, and prediction of stroke using the Congestive heart failure, Hypertension, Age >75, Diabetes mellitus, and prior Stroke or transient ischemic attack (CHADS2) risk stratification scheme
Stephan Rietbrock et al.
AMERICAN HEART JOURNAL (2008)
Rivaroxaban - an oral, direct Factor Xa inhibitor - has potential for the management of patients with heparin-induced thrombocytopenia
Jeanine M. Walenga et al.
BRITISH JOURNAL OF HAEMATOLOGY (2008)
Pharmacokinetics and pharmacodynamics of the direct oral thrombin inhibitor dabigatran in healthy elderly subjects
Joachim Stangier et al.
CLINICAL PHARMACOKINETICS (2008)
Clinical pharmacokinetics and pharmacodynamics of the oral direct thrombin inhibitor dabigatran etexilate
Joachim Stangier
CLINICAL PHARMACOKINETICS (2008)
Dose-escalation study of the pharmacokinetics and pharmacodynamics of rivaroxaban in healthy elderly subjects
Dagmar Kubitza et al.
CURRENT MEDICAL RESEARCH AND OPINION (2008)
Extended duration rivaroxaban versus short-term enoxaparin for the prevention of venous thromboembolism after total hip arthroplasty: a double-blind, randomised controlled trial
Ajay K. Kakkar et al.
LANCET (2008)
Rivaroxaban versus enoxaparin for thromboprophylaxis after hip arthroplasty
Bengt I. Eriksson et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty
Michael R. Lassen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Warfarin Resistance After Total Gastrectomy and Roux-en-Y Esophagojejunostomy
Diana M. Sobieraj et al.
PHARMACOTHERAPY (2008)
Racial/ethnic differences in ischemic stroke rates and the efficacy of warfarin among patients with atrial fibrillation
Albert Yuh-Jer Shen et al.
STROKE (2008)
The metabolism and disposition of the oral direct thrombin inhibitor, dabigatran, in humans
Stefan Blech et al.
DRUG METABOLISM AND DISPOSITION (2008)
Dabigatran with or without concomitant Aspirin compared with Warfarin alone in patients with nonvalvular atrial fibrillation (PETRO study)
Michael D. Ezekowitz et al.
AMERICAN JOURNAL OF CARDIOLOGY (2007)
Oral dabigatran etexilate vs. subcutaneous enoxaparin for the prevention of venous thromboembolism after total knee replacement:: the RE-MODEL randomized trial
B. I. Eriksson et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2007)
The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects
Joachim Stangier et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2007)
Racial/ethnic differences in the risk of intracranial hemorrhage among patients with atrial fibrillation
Albert Yuh-Jer Shen et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2007)
Rivaroxaban (BAY 59-7939) - an oral, direct Factor Xa inhibitor - has no clinically relevant interaction with naproxen
Dagmar Kubitza et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2007)
Body weight has limited influence on the safety, tolerability, pharmacokinetics, or pharmacodynamics of rivaroxaban (BAY 59-7939) in healthy subjects
Dagmar Kubitza et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2007)
Progression of warfarin-associated intracerebral hemorrhage after INR normalization with FFP
Sung B. Lee et al.
NEUROLOGY (2006)
Falls in older people: epidemiology, risk factors and strategies for prevention
Laurence Z. Rubenstein
AGE AND AGEING (2006)
Effect of food, an antacid, and the H2 antagonist ranitidine on the absorption of BAY 59-7939 (Rivaroxaban), an oral, direct factor Xa inhibitor, in healthy subjects
D Kubitza et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2006)
Use and effectiveness of warfarin in medicare beneficiaries with atrial fibrillation
E Birman-Deych et al.
STROKE (2006)
Translating the results of randomized trials into clinical practice - The challenge of warfarin candidacy among hospitalized elderly patients with atrial fibrillation
EM Hylek et al.
STROKE (2006)
Post-stroke seizure and post-stroke epilepsy
P. K. Myint et al.
POSTGRADUATE MEDICAL JOURNAL (2006)
Safety, pharmacodynamics, and pharmacokinetics of single doses of BAY 59-7939, an oral, direct factor Xa inhibitor
D Kubitza et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2005)
A global clinical measure of fitness and frailty in elderly people
K Rockwood et al.
CANADIAN MEDICAL ASSOCIATION JOURNAL (2005)
Pharmacokinetic profile of the oral direct thrombin inhibitor dabigatran etexilate in healthy volunteers and patients undergoing total hip replacement
J Stangier et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2005)
The influence of extreme body weight on clinical outcome of patients with venous thromboembolism:: findings from a prospective registry (RIETE)
R Barba et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2005)
Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients
S Schulman et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2005)
Obesity and the risk of new-onset atrial fibrillation
TJ Wang et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2004)
Oral anticoagulation in surgical procedures: risks and recommendations
M Torn et al.
BRITISH JOURNAL OF HAEMATOLOGY (2003)
Frailty in older adults: Evidence for a phenotype
LP Fried et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2001)
How long after drug ingestion is activated charcoal still effective?
R Green et al.
JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY (2001)
Glomerular hemodynamics in severe obesity
A Chagnac et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2000)