Related references
Note: Only part of the references are listed.Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis
Ievgenia Pastushenko et al.
NATURE (2021)
YAP/TAZ: Drivers of Tumor Growth, Metastasis, and Resistance to Therapy
Barry J. Thompson
BIOESSAYS (2020)
Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription
Qi Li et al.
CELL STEM CELL (2020)
Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche
Manolis Roulis et al.
NATURE (2020)
Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer
Priscilla Cheung et al.
CELL STEM CELL (2020)
Feedback control of Wnt signaling based on ultrastable histidine cluster co-aggregation between Naked/NKD and Axin
Melissa V. Gammons et al.
ELIFE (2020)
Single-cell transcriptomes of the regenerating intestine reveal a revival stem cell
Arshad Ayyaz et al.
NATURE (2019)
Active cell migration is critical for steady-state epithelial turnover in the gut
Denis Krndija et al.
SCIENCE (2019)
Positional information and tissue scaling during development and regeneration
Daniel Capek et al.
DEVELOPMENT (2019)
YAP/TAZ Initiates Gastric Tumorigenesis via Upregulation of MYC
Wonyoung Choi et al.
CANCER RESEARCH (2018)
YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration
Shiro Yui et al.
CELL STEM CELL (2018)
Multiprotein complexes governing Wnt signal transduction
Melissa Gammons et al.
CURRENT OPINION IN CELL BIOLOGY (2018)
Mechanical strain regulates the Hippo pathway in Drosophila
Georgina C. Fletcher et al.
DEVELOPMENT (2018)
RAP2 mediates mechanoresponses of the Hippo pathway
Zhipeng Meng et al.
NATURE (2018)
GLI1-expressing mesenchymal cells form the essential Wnt-secreting niche for colon stem cells
Bahar Degirmenci et al.
NATURE (2018)
Enigma proteins regulate YAP mechanotransduction
Ahmed Elbediwy et al.
JOURNAL OF CELL SCIENCE (2018)
YAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis
Koji Taniguchi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
USP7 Is a Tumor-Specific WNT Activator for APC-Mutated Colorectal Cancer by Mediating β-Catenin Deubiquitination
Laura Novellasdemunt et al.
CELL REPORTS (2017)
Probing the canonicity of the Wnt/Wingless signaling pathway
Alexandra Franz et al.
PLOS GENETICS (2017)
Hippo signalling in intestinal regeneration and cancer
Alex Gregorieff et al.
CURRENT OPINION IN CELL BIOLOGY (2017)
Src Inhibits the Hippo Tumor Suppressor Pathway through Tyrosine Phosphorylation of Lats1
Yuan Si et al.
CANCER RESEARCH (2017)
Integrin signalling regulates YAP and TAZ to control skin homeostasis
Ahmed Elbediwy et al.
DEVELOPMENT (2016)
αE-catenin inhibits a Src-YAP1 oncogenic module that couples tyrosine kinases and the effector of Hippo signaling pathway
Peng Li et al.
GENES & DEVELOPMENT (2016)
Designer matrices for intestinal stem cell and organoid culture
Nikolce Glorevski et al.
NATURE (2016)
Wnt Ligands Secreted by Subepithelial Mesenchymal Cells Are Essential for the Survival of Intestinal Stem Cells and Gut Homeostasis
Tomas Valenta et al.
CELL REPORTS (2016)
CD44 regulates cell proliferation, migration, and invasion via modulation of c-Src transcription in human breast cancer cells
KeeSoo Nam et al.
CELLULAR SIGNALLING (2015)
SOX9 Maintains Reserve Stem Cells and Preserves Radioresistance in Mouse Small Intestine
Kyle C. Roche et al.
GASTROENTEROLOGY (2015)
β-Catenin destruction complex-independent regulation of Hippo-YAP signaling by APC in intestinal tumorigenesis
Jing Cai et al.
GENES & DEVELOPMENT (2015)
Adhesion to fibronectin regulates Hippo signaling via the FAK-Src-PI3K pathway
Nam-Gyun Kim et al.
JOURNAL OF CELL BIOLOGY (2015)
Yap-dependent reprogramming of Lgr5+ stem cells drives intestinal regeneration and cancer
Alex Gregorieff et al.
NATURE (2015)
A gp130-Src-YAP module links inflammation to epithelial regeneration
Koji Taniguchi et al.
NATURE (2015)
Mechanical strain induces E-cadherin-dependent Yap1 and β-catenin activation to drive cell cycle entry
Blair W. Benham-Pyle et al.
SCIENCE (2015)
YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response
Luca Azzolin et al.
CELL (2014)
c-Src drives intestinal regeneration and transformation
Julia B. Cordero et al.
EMBO JOURNAL (2014)
The Intestinal Crypt, A Prototype Stem Cell Compartment
Hans Clevers
CELL (2013)
Restriction of intestinal stem cell expansion and the regenerative response by YAP
Evan R. Barry et al.
NATURE (2013)
Activation of two distinct Sox9-EGFP-expressing intestinal stem cell populations during crypt regeneration after irradiation
Laurianne Van Landeghem et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2012)
β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis
Joseph Rosenbluh et al.
CELL (2012)
A molecular mechanism that links Hippo signalling to the inhibition of Wnt/β-catenin signalling
Masamichi Imajo et al.
EMBO JOURNAL (2012)
Wnt/β-Catenin Signaling Regulates Yes-associated Protein (YAP) Gene Expression in Colorectal Carcinoma Cells
Wesley M. Konsavage et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
A Critical Role for the Wnt Effector Tcf4 in Adult Intestinal Homeostatic Self-Renewal
Johan H. van Es et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
Hippo pathway regulation by cell morphology and stress fibers
Ken-Ichi Wada et al.
DEVELOPMENT (2011)
The Wnt Antagonist Dkk1 Regulates Intestinal Epithelial Homeostasis and Wound Repair
Stefan Koch et al.
GASTROENTEROLOGY (2011)
Role of YAP/TAZ in mechanotransduction
Sirio Dupont et al.
NATURE (2011)
Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance
Dawang Zhou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
CD44 Attenuates Activation of the Hippo Signaling Pathway and Is a Prime Therapeutic Target for Glioblastoma
Yin Xu et al.
CANCER RESEARCH (2010)
The Hippo Pathway Regulates Wnt/β-Catenin Signaling
Xaralabos Varelas et al.
DEVELOPMENTAL CELL (2010)
Focal Adhesion Kinase Is Required for Intestinal Regeneration and Tumorigenesis Downstream of Wnt/c-Myc Signaling
Gabrielle H. Ashton et al.
DEVELOPMENTAL CELL (2010)
The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program
Jing Cai et al.
GENES & DEVELOPMENT (2010)
Interferon-γ Regulates Intestinal Epithelial Homeostasis through Converging β-Catenin Signaling Pathways
Porfirio Nava et al.
IMMUNITY (2010)
Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
Bryan T. MacDonald et al.
DEVELOPMENTAL CELL (2009)
Acute Overexpression of Myc in Intestinal Epithelium Recapitulates Some but Not All the Changes Elicited by Wnt/β-Catenin Pathway Activation
Andrew J. Finch et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Deletion of the WNT target and cancer stem cell marker CD44 in Apc(Min/ plus ) mice attenuates intestinal tumorigenesis
Jurrit Zeilstra et al.
CANCER RESEARCH (2008)
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
Bin Zhao et al.
GENES & DEVELOPMENT (2007)
Wnt/β-Catenin is essential for intestinal Homeostasis and maintenance of intestinal stem cells
Tea Fevr et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium
Pauline Bastide et al.
JOURNAL OF CELL BIOLOGY (2007)
SOX9 is required for the differentiation of paneth cells in the intestinal epithelium
Yuko Mori-Akiyama et al.
GASTROENTEROLOGY (2007)
Myc deletion rescues Apc deficiency in the small intestine
Owen J. Sansom et al.
NATURE (2007)
Rapid loss of intestinal crypts upon conditional deletion of the Wnt/Tcf-4 target gene c-Myc
Vanesa Muncan et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine
P Andreu et al.
DEVELOPMENT (2005)
Inducible Cre-mediated control of gene expression in the murine gastrointestinal tract:: Effect of loss of β-catenin
H Ireland et al.
GASTROENTEROLOGY (2004)
Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1
F Kuhnert et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
OJ Sansom et al.
GENES & DEVELOPMENT (2004)
Canonical Wnt signals are essential for homeostasis of the intestinal epithelium
D Pinto et al.
GENES & DEVELOPMENT (2003)
CD44-initiated cell spreading induces Pyk2 phosphorylation, is mediated by Src family kinases, and is negatively regulated by CD45
RH Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
CD44 interaction with c-Src kinase promotes cortactin-mediated cytoskeleton function and hyaluronic acid-dependent ovarian tumor cell migration
LYW Bourguignon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Linking colorectal cancer to Wnt signaling
M Bienz et al.
CELL (2000)
Stem cells: the intestinal stem cell as a paradigm
SP Bach et al.
CARCINOGENESIS (2000)
Naked cuticle encodes an inducible antagonist of Wnt signalling
WL Zeng et al.
NATURE (2000)