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Olive Oil Consumption Can Prevent Non-communicable Diseases and COVID-19: A Review

Journal

CURRENT PHARMACEUTICAL BIOTECHNOLOGY
Volume 23, Issue 2, Pages 270-284

Publisher

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1389201022666210412143553

Keywords

Bioactive; cardiovascular; cancer; olive oil; oleuropein; oleic acid

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The Mediterranean diet is highly regarded and is associated with the prevention of degenerative diseases and increased longevity. Olive oil consumption is a key feature of this diet, and it is rich in bioactive compounds that have anti-inflammatory and cardioprotective properties. Recent studies suggest that the phytochemicals in olive oil may have potential against SARS-CoV-2. However, there are still gaps in understanding how the phytochemical composition of olive oil is influenced by processing methods and the signaling pathways involved in its health benefits.
The Mediterranean diet is appraised as the premier dietary regimen, and its espousal is correlated with the prevention of degenerative diseases and extended longevity. The consumption of olive oil stands out as the most peculiar feature of the Mediterranean diet. Olive oil rich in various bioactive compounds like oleanolic acid, oleuropein, oleocanthal, and hydroxytyrosol is known for its antiinflammatory as well as cardioprotective property. Recently in silico studies have indicated that phytochemicals present in olive oil are a potential candidate to act against SARS-CoV-2. Although there are many extensive studies on olive oil and its phytochemical composition, however, some lacunas persist in understanding how the phytochemical composition of olive oil is dependent on upstream processing. The signaling pathways regulated by olive oil in the restriction of various diseases are also not clear. For answering these queries, a detailed search of research and review articles published between 1990 to 2019 were reviewed. Olive oil consumption was found to be advantageous for various chronic non-communicable diseases. Olive oil's constituents are having potent anti-inflammatory activities and thus restrict the progression of various inflammation-linked diseases ranging from arthritis to cancer. But it is also notable that the amount and nature of the phytochemical composition of household olive oil are regulated by its upstream processing, and the physicochemical properties of this oil can give a hint regarding the manufacturing method as well as its therapeutic effect. Moreover, daily uptake of olive oil should be monitored as excessive intake can cause body weight gain and a change in the basal metabolic index. So, it can be concluded that the olive oil consumption is beneficial for human health, and particularly for the prevention of cardiovascular diseases, breast cancer, and inflammation. The simple way of processing olive oil is to maintain the polyphenol constituents, whichprovide the protection against non communicable diseases and SARS-CoV-2.

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