Related references
Note: Only part of the references are listed.Engaging chromatin: PRC2 structure meets function
Paul Chammas et al.
BRITISH JOURNAL OF CANCER (2020)
A Dimeric Structural Scaffold for PRC2-PCL Targeting to CpG Island Chromatin
Siming Chen et al.
MOLECULAR CELL (2020)
Histone H2AK119 Mono-Ubiquitination Is Essential for Polycomb-Mediated Transcriptional Repression
Simone Tamburri et al.
MOLECULAR CELL (2020)
PRC1 Catalytic Activity Is Central to Polycomb System Function
Neil P. Blackledge et al.
MOLECULAR CELL (2020)
Structural basis for PRC2 decoding of active histone methylation marks H3K36me2/3
Ksenia Finogenova et al.
ELIFE (2020)
EZHIP/CXorf67 mimics K27M mutated oncohistones and functions as an intrinsic inhibitor of PRC2 function in aggressive posterior fossa ependymoma
Jens-Martin Huebner et al.
NEURO-ONCOLOGY (2019)
Dangerous liaisons: interplay between SWI/SNF, NuRD, and Polycomb in chromatin regulation and cancer
Adrian P. Bracken et al.
GENES & DEVELOPMENT (2019)
Functional Landscape of PCGF Proteins Reveals Both RING1A/B-Dependent-and RING1A/B-Independent-Specific Activities
Andrea Scelfo et al.
MOLECULAR CELL (2019)
Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression
Nadezda A. Fursova et al.
MOLECULAR CELL (2019)
Molecular Mechanisms Directing PRC2 Recruitment and H3K27 Methylation
Anne Laugesen et al.
MOLECULAR CELL (2019)
Dissecting the role of H3K27 acetylation and methylation in PRC2 mediated control of cellular identity
Elisa Lavarone et al.
NATURE COMMUNICATIONS (2019)
PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism
Siddhant U. Jain et al.
NATURE COMMUNICATIONS (2019)
CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism
Andrea Piunti et al.
SCIENCE ADVANCES (2019)
PRC2 functions in development and congenital disorders
Orla Deevy et al.
DEVELOPMENT (2019)
Non-core Subunits of the PRC2 Complex Are Collectively Required for Its Target-Site Specificity
Jonas Westergaard Hojfeldt et al.
MOLECULAR CELL (2019)
PRC2.1 and PRC2.2 Synergize to Coordinate H3K27 Trimethylation
Evan Healy et al.
MOLECULAR CELL (2019)
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells
Roberta Ragazzini et al.
NATURE COMMUNICATIONS (2019)
The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells
Gundula Streubel et al.
MOLECULAR CELL (2018)
Distinct Stimulatory Mechanisms Regulate the Catalytic Activity of Polycomb Repressive Complex 2
Chul-Hwan Lee et al.
MOLECULAR CELL (2018)
Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding
Siming Chen et al.
MOLECULAR CELL (2018)
A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities
Eric Conway et al.
MOLECULAR CELL (2018)
Capturing the Onset of PRC2-Mediated Repressive Domain Formation
Ozgur Oksuz et al.
MOLECULAR CELL (2018)
MTF2 recruits Polycomb Repressive Complex 2 by helical-shape-selective DNA binding
Matteo Perino et al.
NATURE GENETICS (2018)
Accurate H3K27 methylation can be established de novo by SUZ12-directed PRC2
Jonas W. Hojfeldt et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
Cryo-EM structures of PRC2 simultaneously engaged with two functionally distinct nucleosomes
Simon Poepsel et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
Structures of human PRC2 with its cofactors AEBP2 and JARID2
Vignesh Kasinath et al.
SCIENCE (2018)
Accurate H3K27 methylation can be established de novo by SUZ12-directed PRC2
Jonas W. Hojfeldt et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
Cryo-EM structures of PRC2 simultaneously engaged with two functionally distinct nucleosomes
Simon Poepsel et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
Polycomb-like proteins link the PRC2 complex to CpG islands
Haojie Li et al.
NATURE (2017)
Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA
Xueyin Wang et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
DNA binding by PHF1 prolongs PRC2 residence time on chromatin and thereby promotes H3K27 methylation
Jeongyoon Choi et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Mutation of a nucleosome compaction region disrupts Polycomb-mediated axial patterning
Mei Sheng Lau et al.
SCIENCE (2017)
Mechanisms Regulating PRC2 Recruitment and Enzymatic Activity
Daniel Holoch et al.
TRENDS IN BIOCHEMICAL SCIENCES (2017)
Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA
Xueyin Wang et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
DNA binding by PHF1 prolongs PRC2 residence time on chromatin and thereby promotes H3K27 methylation
Jeongyoon Choi et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Genome Regulation by Polycomb and Trithorax: 70 Years and Counting
Bernd Schuettengruber et al.
CELL (2017)
Structure of the PRC2 complex and application to drug discovery
Yi Shi et al.
ACTA PHARMACOLOGICA SINICA (2017)
EPOP Interacts with Elongin BC and USP7 to Modulate the Chromatin Landscape
Robert Liefke et al.
MOLECULAR CELL (2016)
EPOP Functionally Links Elongin and Polycomb in Pluripotent Stem Cells
Malte Beringer et al.
MOLECULAR CELL (2016)
Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2
Sarah Cooper et al.
NATURE COMMUNICATIONS (2016)
A High-Density Map for Navigating the Human Polycomb Complexome
Simon Hauri et al.
CELL REPORTS (2016)
PRC2 mediated H3K27 methylations in cellular identity and cancer
Eric Conway et al.
CURRENT OPINION IN CELL BIOLOGY (2015)
A chromatin-independent role of Polycomb-like 1 to stabilize p53 and promote cellular quiescence
Gerard L. Brien et al.
GENES & DEVELOPMENT (2015)
Jarid2 Methylation via the PRC2 Complex Regulates H3K27me3 Deposition during Cell Differentiation
Serena Sanulli et al.
MOLECULAR CELL (2015)
Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2
Lianying Jiao et al.
SCIENCE (2015)
Variant PRC1 Complex-Dependent H2A Ubiquitylation Drives PRC2 Recruitment and Polycomb Domain Formation
Neil P. Blackledge et al.
CELL (2014)
Polycomb-Dependent H3K27me1 and H3K27me2 Regulate Active Transcription and Enhancer Fidelity
Karin J. Ferrari et al.
MOLECULAR CELL (2014)
Histone H2A monoubiquitination promotes histone H3 methylation in Polycomb repression
Reinhard Kalb et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2014)
NAR Breakthrough Article A dimeric state for PRC2
Chen Davidovich et al.
NUCLEIC ACIDS RESEARCH (2014)
Reciprocal interactions of human C10orf12 and C17orf96 with PRC2 revealed by BioTAP-XL cross-linking and affinity purification
Artyom A. Alekseyenko et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Targeting Polycomb to Pericentric Heterochromatin in Embryonic Stem Cells Reveals a Role for H2AK119u1 in PRC2 Recruitment
Sarah Cooper et al.
CELL REPORTS (2014)
SAM Domain Polymerization Links Subnuclear Clustering of PRC1 to Gene Silencing
Kyoichi Isono et al.
DEVELOPMENTAL CELL (2013)
Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity
Cecilia Ballare et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
Polycomb PHF19 binds H3K36me3 and recruits PRC2 and demethylase NO66 to embryonic stem cell genes during differentiation
Gerard L. Brien et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1
Catherine A. Musselman et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
Dense Chromatin Activates Polycomb Repressive Complex 2 to Regulate H3 Lysine 27 Methylation
Wen Yuan et al.
SCIENCE (2012)
Molecular architecture of human polycomb repressive complex 2
Claudio Ciferri et al.
ELIFE (2012)
Chromatin-modifying Complex Component Nurf55/p55 Associates with Histones H3 and H4 and Polycomb Repressive Complex 2 Subunit Su(z) 12 through Partially Overlapping Binding Sites
Agnieszka J. Nowak et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Histone Methylation by PRC2 Is Inhibited by Active Chromatin Marks
Frank W. Schmitges et al.
MOLECULAR CELL (2011)
JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells
Diego Pasini et al.
NATURE (2010)
Discovery and characterization of chromatin states for systematic annotation of the human genome
Jason Ernst et al.
NATURE BIOTECHNOLOGY (2010)
Role of the polycomb protein EED in the propagation of repressive histone marks
Raphael Margueron et al.
NATURE (2009)
A model for transmission of the H3K27me3 epigenetic mark
Klaus H. Hansen et al.
NATURE CELL BIOLOGY (2008)
Structural basis for specific binding of polycomb chromodomain to histone H3 methylated at Lys 27
JR Min et al.
GENES & DEVELOPMENT (2003)
Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 bv Polvcomb and HP1 chromodomains
W Fischle et al.
GENES & DEVELOPMENT (2003)