Journal
CURRENT MEDICINAL CHEMISTRY
Volume 28, Issue 42, Pages 8692-8710Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/0929867328666210405125348
Keywords
Bioactive hydrogel; antibacterial hydrogel; wound healing; environmentally responsive hydrogel; drug delivery system; tissue engineering
Funding
- National Natural Science Foundation of China [82173742, 81573285]
- Natural Science Basic Research Plan in Shaanxi Province of China [2020SF-240, 2018JM7071]
- Fundamental Research Funds for the Central Universities [xzy032020003]
- Bao'an TCM Development Foundation [2020KJCX-KTYJ-200]
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Hydrogels are hydrophilic and water-soluble polymer systems with a three-dimensional network structure, known for their high moisturizing properties, good biocompatibility, and controlled biodegradability. They have been widely used in wound dressing and other fields. Recent years have seen an increase in the use of antibacterial gel dressings for wound healing, with a focus on the application of environmentally responsive intelligent hydrogel delivery systems. The future development prospects and challenges of hydrogel wound dressings are also discussed in this article.
Hydrogels are hydrophilic but water-soluble polymer systems with a three-dimensional network structure. They can absorb large amounts of water and maintain their shape and remain soft. The high-moisturizing properties, good biocompatibility, and controlled biodegradability of hydrogels have allowed them to be widely used in wound dressing, tissue engineering, controlled drug delivery systems, and other fields. This article reviews the most widely used antibacterial gel dressings for wound healing in recent years and focuses on the application of an environmentally responsive intelligent hydro gel delivery system. Finally, the development prospects and challenges of hydrogel wound dressings are forecasted.
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