4.6 Review

Advances in Polyaniline for Biomedical Applications

Journal

CURRENT MEDICINAL CHEMISTRY
Volume 29, Issue 2, Pages 329-357

Publisher

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/0929867328666210419135519

Keywords

Polyaniline; composites; blends; biomedicine; synthesis; applications

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Polyaniline (PANI) is a promising material in the biomedical field due to its conductivity, biocompatibility, and low toxicity. However, its low solubility and processability pose challenges for practical applications. Different methods have been developed to overcome these limitations. This review highlights recent advances in PANI applications in biomedical fields and provides insights into the synthesis of more innovative materials in the future.
Conducting polymers are an outstanding class of materials characterized by electroconductive properties that make them good candidates for applications in several sectors. Among them, polyaniline (PANI) is unique for its extraordinary ability to conduct electricity, biocompatibility, and low toxicity. In spite of its surprising features, to date, PANI has not found application in practical uses due to its low solubility and processability. In order to overcome these limitations, different approaches have been developed, such as polymer grafting processes, PANI-based composites, and blends preparation. The present review describes the most recent advances on PANI applications in biomedical fields, such as antioxidant, antimicrobial and antivirus activity, drug delivery, cancer therapy, etc. In this article, synthetic procedures are also reported which are crucial for the realization of more innovative materials in the future.

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