4.7 Review

Can be marine bioactive peptides (MBAs) lead the future of foodomics for human health?

Journal

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
Volume 62, Issue 25, Pages 7072-7116

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/10408398.2021.1910482

Keywords

clinical data; marine drugs; molecular pharmacology; structure-activity relationship; synthetic approaches

Ask authors/readers for more resources

Marine bioactive peptides derived from diverse marine species have shown potential in treating various diseases and promoting health benefits. Some marine peptides have been approved for commercial use, while many are still under pre-clinical and clinical trials for their therapeutic and biological potential.
Marine organisms are considered a cache of biologically active metabolites with pharmaceutical, functional, and nutraceutical properties. Among these, marine bioactive peptides (MBAs) present in diverse marine species (fish, sponges, cyanobacteria, fungi, ascidians, seaweeds, & mollusks) have acquired attention owing to their broad-spectrum health-promoting benefits. Nowadays, scientists are keener exploring marine bioactive peptides precisely due to their unique structural and biological properties. These MBAs have reported ameliorating potential against different diseases like hypertension, diabetes, obesity, HIV, cancer, oxidation, and inflammation. Furthermore, MBAs isolated from various marine organisms may also have a beneficial role in the cosmetic, nutraceutical, and food industries. Few marine peptides and their derivative are approved for commercial use, while many MBAs are in various pre-clinical and clinical trials. This review mainly focuses on the diversity of marine bioactive peptides in marine organisms and their production procedures, such as chemical and enzymatic hydrolysis. Moreover, MBAs' therapeutic and biological potential has also been critically discussed herein, along with their status in drug discovery, pre-clinical and clinical trials.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available