4.8 Review

Biologically significant pyrimidine appended optical sensors: An inclusive anthology of literature from 2005 to 2020

Journal

COORDINATION CHEMISTRY REVIEWS
Volume 435, Issue -, Pages -

Publisher

ELSEVIER SCIENCE SA
DOI: 10.1016/j.ccr.2021.213798

Keywords

Pyrimidines; Biological properties; Heterocycles; Sensors; Fluorescence

Funding

  1. CSIR-New Delhi [09/135(0911)2020EMR-I]
  2. DST PURSE-II [48/RPC]

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Compounds containing heteroatoms and their derivatives are important in organic chemistry, with N-heterocycles commonly used as recognition units for optical sensors and in biological applications. Pyrimidine derivatives are suitable for sensing materials and have various biological and medicinal applications, thanks to their ability to form coordination and hydrogen bonds. This review covers various pyrimidine-based optical sensors from 2005 to 2020.
Compounds containing heteroatoms and their derivatives represent a very significant section in organic chemistry. A number of N-heterocycles such as triazole, thiazole, pyridine, pyrrole, quinoline, or imidazole as well as their derivatives have been commonly employed as recognition units for the synthesis of optical sensors beside their biological applications. In this category, pyrimidine derivatives are suitable objects for utilising as exquisite sensing materials and also have a range of biological and medicinal applications. The competence of pyrimidine derivatives to form both coordination as well as hydrogen bond makes them appropriate to be used as sensing probes. This review comprises of various pyrimidine based optical sensors with the recent literature from 2005 to 2020. (C) 2021 Elsevier B.V. All rights reserved.

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