Journal
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
Volume 202, Issue -, Pages -Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.cmpb.2021.105959
Keywords
ECG Analysis; ECG Language processing; Deep learning; Heart arrhythmia; Bidirectional recurrent neural networks
Categories
Funding
- National Science Foundation [1657260]
- National Institute On Minority Health And Health Disparities of the National Institutes of Health [U54MD012388]
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This study proposes a novel ECG analysis technique called ECG language processing (ELP) to enable computers to understand ECG signals similar to how physicians do. Experimental results show that the proposed approach can be applied to various biomedical applications and achieve remarkable performance in heartbeat classification and atrial fibrillation detection in ECG signals.
Background: A language is constructed of a finite/infinite set of sentences composing of words. Similar to natural languages, the Electrocardiogram (ECG) signal, the most common noninvasive tool to study the functionality of the heart and diagnose several abnormal arrhythmias, is made up of sequences of three or four distinct waves, including the P-wave, QRS complex, T-wave, and U-wave. An ECG signal may contain several different varieties of each wave (e.g., the QRS complex can have various appearances). For this reason, the ECG signal is a sequence of heartbeats similar to sentences in natural languages) and each heartbeat is composed of a set of waves (similar to words in a sentence) of different morphologies. Methods: Analogous to natural language processing (NLP), which is used to help computers understand and interpret the human's natural language, it is possible to develop methods inspired by NLP to aid computers to gain a deeper understanding of Electrocardiogram signals. In this work, our goal is to propose a novel ECG analysis technique, ECG language processing (ELP), focusing on empowering computers to understand ECG signals in a way physicians do. Results: We evaluated the proposed approach on two tasks, including the classification of heartbeats and the detection of atrial fibrillation in the ECG signals. Overall, our technique resulted in better performance or comparable performance with smaller neural networks compared to other deep neural networks and existing algorithms. Conclusion: Experimental results on three databases (i.e., PhysioNet's MIT-BIH, MIT-BIH AFIB, and PhysioNet Challenge 2017 AFIB Dataset databases) reveal that the proposed approach as a general idea can be applied to a variety of biomedical applications and can achieve remarkable performance. (c) 2021 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license ( http://creativecommons.org/licenses/by-nc-nd/4.0/ )
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