Journal
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
Volume 625, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.colsurfa.2021.126662
Keywords
Nanostructured lipid carrier; Anti-microbial resistance; Drug delivery; Inhibition zone; Magnetic nanoparticles; Targeting
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Funding
- Natural Science Foundation of Shandong Province [ZR2018MC010]
- Chinese Scholarship Council (CSC)
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The study demonstrates that nanostructured lipid-based carriers (NLCs) can serve as efficient targeted drug delivery systems for eradicating six common pathogens, with slow drug release capabilities. Biological studies have shown that these nanostructures possess strong antibacterial potency.
Nanostructured lipid-based carriers (NLCs) efficiently improved as potential targeted drug delivery for six common pathogens eradication. Transmission electron microscopy (TEM), scanning electron microscopy (SEM), and dynamic light scattering (DLS) showed that all the formulas fully characterized nanosize and surfacenegative charge and presented the drug's slow release even after 48 h in vitro. The biological studies proved that the nanostructures' antibacterial potency is in the order of Fe3O4
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