Journal
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS
Volume 20, Issue 10, Pages 904-941Publisher
BENTHAM SCIENCE PUBL
DOI: 10.2174/1871527320666210420135437
Keywords
Alzheimer's disease; natural plant products; pathogenesis; treatment; AD symptoms; secondary metabolites
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Alzheimer's Disease is a major neurodegenerative disorder with limited medication options available, but natural plant products have shown potential in reducing disease progression with fewer side effects.
Alzheimer's Disease (AD) is one of the major neurodegenerative disorders. Deposition of amyloid fibrils and tau protein is associated with various pathological symptoms. Currently, limited medication is available for AD treatment. Most of the drugs are basically cholinesterase inhibitors and associated with various side effects. Natural plant products have shown potential as a therapeutic agent for the treatment of AD symptoms. A variety of secondary metabolites such as flavonoids, tannins, terpenoids, alkaloids, and phenols are used to reduce the progression of the disease. Plant products have fewer or no side effects and are easily available. The present review gives a detailed account of the potential of natural plant products against AD symptoms.
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