4.4 Review

Rheumatology-led pregnancy clinic: patient-centred approach

Journal

CLINICAL RHEUMATOLOGY
Volume 40, Issue 10, Pages 3875-3882

Publisher

SPRINGER LONDON LTD
DOI: 10.1007/s10067-021-05690-y

Keywords

Autoimmune rheumatic diseases; Contraception; Card outcomes; Decision aid; pregnancy; PROMs; Rheumatoid arthritis; SLE

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Autoimmune rheumatic diseases can negatively impact fertility and pregnancy outcomes, highlighting the importance of reproductive health care as a key component of comprehensive care for patients with these conditions. Pregnancy may accelerate disease progression in some cases, while the activity of certain diseases may be influenced by contraceptive methods.
Autoimmune rheumatic diseases (ARDs), which include all types of inflammatory arthritis as well as systemic Lupus, are known to have a detrimental effect on both fertility and pregnancy outcomes. Consequently, reproductive health care is considered a principle constituent of comprehensive care for all patients with rheumatic ailments seen in the standard practice. Whilst pregnancy-associated complications have been reported in lupus, rheumatoid arthritis, and Sjogren's syndrome, in some conditions such as lupus, antiphospholipid syndrome, inflammatory myopathies, and vasculitis, the pregnancy may accelerate the disease progression. Furthermore, the activity of some diseases such as lupus and antiphospholipid syndrome may be augmented by some contraceptive methods. Therapeutically, some patients are prescribed medications, such as methotrexate and mycophenolate which have potentially teratogenic effect. Therefore, to be able to help those patients, family planning should be patient-centred with decision-making tailored to the individual's disease status. For those healthcare professionals interested in reproductive health care for their patients living with autoimmune rheumatic diseases, this review summarizes the available information in the literature and offers practical suggestions of patient-centred care in a dedicated rheumatology-led pregnancy clinic.

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