Journal
CLINICAL RADIOLOGY
Volume 76, Issue 8, Pages -Publisher
W B SAUNDERS CO LTD
DOI: 10.1016/j.crad.2021.04.006
Keywords
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Funding
- Ministry of Science and Technology, R.O.C. [MOST 107-2314-B-016021-MY2]
- Tri-Service General Hospital, National Defense Medical Center-National Taiwan University of Science and Technology Joint Research Program [TSGH-A109002, TSGH-C-107-010]
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The study compared the performance and reading time of different readers using CAD for lung nodule detection. It was found that both the second-reading and concurrent-reading modes improved detection performance for all readers, with the concurrent-reading mode being more efficient for both junior and senior readers.
AIM: To compare the performance and reading time of different readers using automatic artificial intelligence (AI)-powered computer-aided detection (CAD) to detect lung nodules in different reading modes. MATERIALS AND METHODS: One hundred and fifty multidetector computed tomography (CT) datasets containing 340 nodules <= 10 mm in diameter were collected retrospectively. A CAD with vessel-suppressed function was used to interpret the images. Three junior and three senior readers were assigned to read (1) CT images without CAD, (2) second-read using CAD in which CAD was applied only after initial unassisted assessment, and (3) a concurrent read with CAD in which CAD was applied at the start of assessment. Diagnostic performances and reading times were compared using analysis of variance. RESULTS: For all readers, the mean sensitivity improved from 64% (95% confidence interval [CI]: 62%, 66%) for the without-CAD mode to 82% (95% CI: 80%, 84%) for the second-reading mode and to 80% (95% CI: 79%, 82%) for the concurrent-reading mode (p<0.001). There was no significant difference between the two modes in terms of the mean sensitivity, specificity, and area under the receiver operating characteristic curve (AUC) for both junior and senior readers and all readers (p>0.05). The reading time of all readers was significantly shorter for the concurrent-reading mode (124 +/- 25 seconds) compared to without CAD (156 +/- 34 seconds; p<0.001) and the second-reading mode (197 +/- 46 seconds; p<0.001). CONCLUSION: In CAD for lung nodules at CT, the second-reading mode and concurrent-reading mode may improve detection performance for all readers in both screening and clinical routine practice. Concurrent use of CAD is more efficient for both junior and senior readers. (C) 2021 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.
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